6JD2
Crystal structure of Sulfolobus solfataricus ketol-acid reductoisomerase (Sso-KARI) in complex with Mg2+ at pH8.5
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004455 | molecular_function | ketol-acid reductoisomerase activity |
A | 0008652 | biological_process | amino acid biosynthetic process |
A | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
A | 0009097 | biological_process | isoleucine biosynthetic process |
A | 0009099 | biological_process | valine biosynthetic process |
A | 0016491 | molecular_function | oxidoreductase activity |
B | 0004455 | molecular_function | ketol-acid reductoisomerase activity |
B | 0008652 | biological_process | amino acid biosynthetic process |
B | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
B | 0009097 | biological_process | isoleucine biosynthetic process |
B | 0009099 | biological_process | valine biosynthetic process |
B | 0016491 | molecular_function | oxidoreductase activity |
C | 0004455 | molecular_function | ketol-acid reductoisomerase activity |
C | 0008652 | biological_process | amino acid biosynthetic process |
C | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
C | 0009097 | biological_process | isoleucine biosynthetic process |
C | 0009099 | biological_process | valine biosynthetic process |
C | 0016491 | molecular_function | oxidoreductase activity |
D | 0004455 | molecular_function | ketol-acid reductoisomerase activity |
D | 0008652 | biological_process | amino acid biosynthetic process |
D | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
D | 0009097 | biological_process | isoleucine biosynthetic process |
D | 0009099 | biological_process | valine biosynthetic process |
D | 0016491 | molecular_function | oxidoreductase activity |
E | 0004455 | molecular_function | ketol-acid reductoisomerase activity |
E | 0008652 | biological_process | amino acid biosynthetic process |
E | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
E | 0009097 | biological_process | isoleucine biosynthetic process |
E | 0009099 | biological_process | valine biosynthetic process |
E | 0016491 | molecular_function | oxidoreductase activity |
F | 0004455 | molecular_function | ketol-acid reductoisomerase activity |
F | 0008652 | biological_process | amino acid biosynthetic process |
F | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
F | 0009097 | biological_process | isoleucine biosynthetic process |
F | 0009099 | biological_process | valine biosynthetic process |
F | 0016491 | molecular_function | oxidoreductase activity |
G | 0004455 | molecular_function | ketol-acid reductoisomerase activity |
G | 0008652 | biological_process | amino acid biosynthetic process |
G | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
G | 0009097 | biological_process | isoleucine biosynthetic process |
G | 0009099 | biological_process | valine biosynthetic process |
G | 0016491 | molecular_function | oxidoreductase activity |
H | 0004455 | molecular_function | ketol-acid reductoisomerase activity |
H | 0008652 | biological_process | amino acid biosynthetic process |
H | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
H | 0009097 | biological_process | isoleucine biosynthetic process |
H | 0009099 | biological_process | valine biosynthetic process |
H | 0016491 | molecular_function | oxidoreductase activity |
I | 0004455 | molecular_function | ketol-acid reductoisomerase activity |
I | 0008652 | biological_process | amino acid biosynthetic process |
I | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
I | 0009097 | biological_process | isoleucine biosynthetic process |
I | 0009099 | biological_process | valine biosynthetic process |
I | 0016491 | molecular_function | oxidoreductase activity |
J | 0004455 | molecular_function | ketol-acid reductoisomerase activity |
J | 0008652 | biological_process | amino acid biosynthetic process |
J | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
J | 0009097 | biological_process | isoleucine biosynthetic process |
J | 0009099 | biological_process | valine biosynthetic process |
J | 0016491 | molecular_function | oxidoreductase activity |
K | 0004455 | molecular_function | ketol-acid reductoisomerase activity |
K | 0008652 | biological_process | amino acid biosynthetic process |
K | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
K | 0009097 | biological_process | isoleucine biosynthetic process |
K | 0009099 | biological_process | valine biosynthetic process |
K | 0016491 | molecular_function | oxidoreductase activity |
L | 0004455 | molecular_function | ketol-acid reductoisomerase activity |
L | 0008652 | biological_process | amino acid biosynthetic process |
L | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
L | 0009097 | biological_process | isoleucine biosynthetic process |
L | 0009099 | biological_process | valine biosynthetic process |
L | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue BME A 401 |
Chain | Residue |
A | GLU279 |
A | HOH605 |
B | ARG264 |
B | LYS267 |
site_id | AC2 |
Number of Residues | 2 |
Details | binding site for residue MG A 402 |
Chain | Residue |
A | ASP191 |
A | GLU195 |
site_id | AC3 |
Number of Residues | 3 |
Details | binding site for residue MG A 403 |
Chain | Residue |
A | GLU227 |
A | GLU233 |
B | ASP191 |
site_id | AC4 |
Number of Residues | 3 |
Details | binding site for residue MG A 404 |
Chain | Residue |
A | ASP191 |
B | GLU227 |
B | GLU233 |
site_id | AC5 |
Number of Residues | 5 |
Details | binding site for residue BME B 401 |
Chain | Residue |
A | ARG264 |
A | LYS267 |
A | HOH620 |
B | GLU279 |
B | HOH505 |
site_id | AC6 |
Number of Residues | 2 |
Details | binding site for residue MG B 402 |
Chain | Residue |
B | ASP191 |
B | GLU195 |
site_id | AC7 |
Number of Residues | 5 |
Details | binding site for residue BME C 500 |
Chain | Residue |
C | GLU279 |
D | ARG264 |
D | LYS267 |
D | HOH522 |
D | HOH533 |
site_id | AC8 |
Number of Residues | 2 |
Details | binding site for residue MG C 501 |
Chain | Residue |
C | ASP191 |
C | GLU195 |
site_id | AC9 |
Number of Residues | 3 |
Details | binding site for residue MG C 502 |
Chain | Residue |
C | GLU227 |
C | GLU233 |
D | ASP191 |
site_id | AD1 |
Number of Residues | 3 |
Details | binding site for residue MG D 401 |
Chain | Residue |
C | ASP191 |
D | GLU227 |
D | GLU233 |
site_id | AD2 |
Number of Residues | 5 |
Details | binding site for residue BME D 402 |
Chain | Residue |
C | ARG264 |
C | LYS267 |
D | GLU279 |
D | TYR282 |
D | HOH518 |
site_id | AD3 |
Number of Residues | 3 |
Details | binding site for residue MG D 403 |
Chain | Residue |
C | SER254 |
D | ASP191 |
D | GLU195 |
site_id | AD4 |
Number of Residues | 4 |
Details | binding site for residue BME E 500 |
Chain | Residue |
E | GLU279 |
E | HOH602 |
F | ARG264 |
F | LYS267 |
site_id | AD5 |
Number of Residues | 2 |
Details | binding site for residue MG E 501 |
Chain | Residue |
E | ASP191 |
E | GLU195 |
site_id | AD6 |
Number of Residues | 5 |
Details | binding site for residue MG E 502 |
Chain | Residue |
E | GLU227 |
E | GLU233 |
E | HOH601 |
E | HOH613 |
F | ASP191 |
site_id | AD7 |
Number of Residues | 3 |
Details | binding site for residue MG F 401 |
Chain | Residue |
E | ASP191 |
F | GLU227 |
F | GLU233 |
site_id | AD8 |
Number of Residues | 5 |
Details | binding site for residue BME F 402 |
Chain | Residue |
E | ARG264 |
E | LYS267 |
E | HOH625 |
F | GLU279 |
F | TYR282 |
site_id | AD9 |
Number of Residues | 3 |
Details | binding site for residue MG F 403 |
Chain | Residue |
E | SER254 |
F | ASP191 |
F | GLU195 |
site_id | AE1 |
Number of Residues | 5 |
Details | binding site for residue BME G 500 |
Chain | Residue |
G | GLU279 |
G | HOH604 |
G | HOH627 |
H | ARG264 |
H | LYS267 |
site_id | AE2 |
Number of Residues | 2 |
Details | binding site for residue MG G 501 |
Chain | Residue |
G | ASP191 |
G | GLU195 |
site_id | AE3 |
Number of Residues | 3 |
Details | binding site for residue MG G 502 |
Chain | Residue |
G | GLU227 |
G | GLU233 |
H | ASP191 |
site_id | AE4 |
Number of Residues | 3 |
Details | binding site for residue MG H 401 |
Chain | Residue |
G | ASP191 |
H | GLU227 |
H | GLU233 |
site_id | AE5 |
Number of Residues | 4 |
Details | binding site for residue BME H 402 |
Chain | Residue |
G | ARG264 |
H | ASN278 |
H | GLU279 |
H | TYR282 |
site_id | AE6 |
Number of Residues | 2 |
Details | binding site for residue MG H 403 |
Chain | Residue |
H | ASP191 |
H | GLU195 |
site_id | AE7 |
Number of Residues | 4 |
Details | binding site for residue BME I 500 |
Chain | Residue |
I | GLU279 |
I | HOH603 |
J | ARG264 |
J | LYS267 |
site_id | AE8 |
Number of Residues | 2 |
Details | binding site for residue MG I 501 |
Chain | Residue |
I | ASP191 |
I | GLU195 |
site_id | AE9 |
Number of Residues | 3 |
Details | binding site for residue MG I 502 |
Chain | Residue |
I | GLU227 |
I | GLU233 |
J | ASP191 |
site_id | AF1 |
Number of Residues | 3 |
Details | binding site for residue MG J 401 |
Chain | Residue |
I | ASP191 |
J | GLU227 |
J | GLU233 |
site_id | AF2 |
Number of Residues | 4 |
Details | binding site for residue BME J 402 |
Chain | Residue |
I | ARG264 |
I | LYS267 |
J | GLU279 |
J | HOH533 |
site_id | AF3 |
Number of Residues | 2 |
Details | binding site for residue MG J 403 |
Chain | Residue |
J | ASP191 |
J | GLU195 |
site_id | AF4 |
Number of Residues | 5 |
Details | binding site for residue BME K 500 |
Chain | Residue |
K | GLU279 |
K | HOH660 |
L | ARG264 |
L | LYS267 |
L | HOH554 |
site_id | AF5 |
Number of Residues | 2 |
Details | binding site for residue MG K 501 |
Chain | Residue |
K | ASP191 |
K | GLU195 |
site_id | AF6 |
Number of Residues | 3 |
Details | binding site for residue MG K 502 |
Chain | Residue |
K | GLU227 |
K | GLU233 |
L | ASP191 |
site_id | AF7 |
Number of Residues | 3 |
Details | binding site for residue MG L 401 |
Chain | Residue |
K | ASP191 |
L | GLU227 |
L | GLU233 |
site_id | AF8 |
Number of Residues | 4 |
Details | binding site for residue BME L 402 |
Chain | Residue |
K | ARG264 |
K | LYS267 |
K | HOH632 |
L | GLU279 |
site_id | AF9 |
Number of Residues | 3 |
Details | binding site for residue MG L 403 |
Chain | Residue |
K | SER254 |
L | ASP191 |
L | GLU195 |