1ZKZ
| Crystal Structure of BMP9 | Descriptor: | Growth/differentiation factor 2 | Authors: | Brown, M.A, Zhao, Q, Baker, K.A, Naik, C, Chen, C, Pukac, L, Singh, M, Tsareva, T, Parice, Y, Mahoney, A, Roschke, V, Sanyal, I, Choe, S. | Deposit date: | 2005-05-04 | Release date: | 2005-05-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Crystal structure of BMP-9 and functional interactions with pro-region and receptors J.Biol.Chem., 280, 2005
|
|
1EDP
| |
1BC4
| THE SOLUTION STRUCTURE OF A CYTOTOXIC RIBONUCLEASE FROM THE OOCYTES OF RANA CATESBEIANA (BULLFROG), NMR, 15 STRUCTURES | Descriptor: | RIBONUCLEASE | Authors: | Chang, C.-F, Chen, C, Chen, Y.-C, Hom, K, Huang, R.-F, Huang, T. | Deposit date: | 1998-05-05 | Release date: | 1998-10-14 | Last modified: | 2019-12-25 | Method: | SOLUTION NMR | Cite: | The solution structure of a cytotoxic ribonuclease from the oocytes of Rana catesbeiana (bullfrog). J.Mol.Biol., 283, 1998
|
|
5X8Y
| A Mutation identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in vitro | Descriptor: | ZIKV NS1 | Authors: | Wang, D, Chen, C, Liu, S, Zhou, H, Yang, K, Zhao, Q, Ji, X, Chen, C, Xie, W, Wang, Z, Mi, L.Z, Yang, H. | Deposit date: | 2017-03-03 | Release date: | 2017-05-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.817 Å) | Cite: | A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in Vitro Sci Rep, 7, 2017
|
|
4ZXU
| 2.85 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) H448F/P449M double mutant from Staphylococcus aureus in complex with NAD+ and BME-free Cys289 | Descriptor: | Betaine-aldehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION | Authors: | Halavaty, A.S, Minasov, G, Chen, C, Joo, J.C, Yakunin, A.F, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2015-05-20 | Release date: | 2015-06-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | 2.85 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) H448F/P449M double mutant from Staphylococcus aureus in complex with NAD+ and BME-free Cys289. To be Published
|
|
8X7A
| Treprostinil bound Prostacyclin Receptor G protein complex | Descriptor: | 2-[[(1~{R},2~{R},3~{a}~{S},9~{a}~{S})-2-oxidanyl-1-[(3~{S})-3-oxidanyloctyl]-2,3,3~{a},4,9,9~{a}-hexahydro-1~{H}-cyclopenta[g]naphthalen-5-yl]oxy]ethanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Wang, J.J, Jin, S, Zhang, H, Xu, Y, Hu, W, Jiang, Y, Chen, C, Wang, D.W, Xu, H.E, Wu, C. | Deposit date: | 2023-11-23 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.56 Å) | Cite: | Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs. Sci Adv, 10, 2024
|
|
8X79
| MRE-269 bound Prostacyclin Receptor G protein complex | Descriptor: | 2-[4-[(5,6-diphenylpyrazin-2-yl)-propan-2-yl-amino]butoxy]ethanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Wang, J.J, Jin, S, Zhang, H, Xu, Y, Hu, W, Jiang, Y, Chen, C, Wang, D.W, Xu, H.E, Wu, C. | Deposit date: | 2023-11-23 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.41 Å) | Cite: | Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs. Sci Adv, 10, 2024
|
|
3GCX
| PCSK9:EGFA (pH 7.4) | Descriptor: | CALCIUM ION, Low-density lipoprotein receptor, Proprotein convertase subtilisin/kexin type 9 | Authors: | McNutt, M.C, Kwon, H.J, Chen, C, Chen, J.R, Horton, J.D, Lagace, T.A. | Deposit date: | 2009-02-22 | Release date: | 2009-03-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Antagonism of Secreted PCSK9 Increases Low Density Lipoprotein Receptor Expression in HepG2 Cells. J.Biol.Chem., 284, 2009
|
|
5BQX
| Crystal structure of human STING in complex with 3'2'-cGAMP | Descriptor: | 3'2'-cGAMP, Stimulator of interferon genes protein | Authors: | Wu, J, Zhang, X, Chen, Z.J, Chen, C. | Deposit date: | 2015-05-29 | Release date: | 2015-06-24 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis for the specific recognition of the metazoan cyclic GMP-AMP by the innate immune adaptor protein STING. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
2LJV
| Solution structure of Rhodostomin G50L mutant | Descriptor: | Disintegrin rhodostomin | Authors: | Chuang, W, Shiu, J, Chen, C, Chen, Y, Chang, Y, Huang, C. | Deposit date: | 2011-09-29 | Release date: | 2012-10-03 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Design of Integrin AlphaVbeta3-Specific Disintegrin for Cancer Therapy To be Published
|
|
6UHX
| Crystal structure of YIR035C short chain dehydrogenases/reductase from Saccharomyces cerevisiae | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Uncharacterized oxidoreductase YIR035C | Authors: | Stogios, P.J, Skarina, T, Chen, C, Kagan, O, Iakounine, A, Savchenko, A. | Deposit date: | 2019-09-29 | Release date: | 2020-08-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structure of YIR035C short chain dehydrogenases/reductase from Saccharomyces cerevisiae To Be Published
|
|
1JLZ
| Solution Structure of a K+-Channel Blocker from the Scorpion Toxin of Tityus cambridgei | Descriptor: | Tityustoxin alpha-KTx | Authors: | Wang, I, Wu, S.-H, Chang, H.-K, Shieh, R.-C, Yu, H.-M, Chen, C. | Deposit date: | 2001-07-17 | Release date: | 2002-02-06 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of a K(+)-channel blocker from the scorpion Tityus cambridgei. Protein Sci., 11, 2002
|
|
1X37
| Structure of Bacillus subtilis Lon protease SSD domain | Descriptor: | ATP-dependent protease La 1 | Authors: | Wang, I, Lou, Y.C, Lo, S.C, Lee, Y.L, Wu, S.H, Chen, C. | Deposit date: | 2005-04-30 | Release date: | 2005-10-30 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural basis and DNA binding property of SSD domain of Bacillus subtilis Lon protease to be published
|
|
1XHH
| Solution Structure of porcine beta-microseminoprotein | Descriptor: | beta-microseminoprotein | Authors: | Wang, I, Lou, Y.C, Wu, K.P, Wu, S.H, Chang, W.C, Chen, C. | Deposit date: | 2004-09-20 | Release date: | 2005-03-20 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Novel solution structure of porcine beta-microseminoprotein J.Mol.Biol., 346, 2005
|
|
1QLY
| NMR Study of the SH3 Domain From Bruton's Tyrosine Kinase, 20 Structures | Descriptor: | TYROSINE-PROTEIN KINASE BTK | Authors: | Tzeng, S.R, Lou, Y.C, Pai, M.T, Chen, C, Chen, S.H, Cheng, J.Y. | Deposit date: | 1999-09-20 | Release date: | 1999-12-14 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Human Btk SH3 Domain Complexed with a Proline-Rich Peptide from P120Cbl J.Biomol.NMR, 16, 2000
|
|
5DIB
| 2.25 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) Y450L point mutant from Staphylococcus aureus in complex with NAD+ and BME-modified Cys289 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Betaine aldehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Halavaty, A.S, Minasov, G, Chen, C, Joo, J.C, Yakunin, A.F, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2015-08-31 | Release date: | 2015-10-14 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | 2.25 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) Y450L point mutant from Staphylococcus aureus in complex with NAD+ and BME-modified Cys289 To Be Published
|
|
4B27
| Trp RNA-binding attenuation protein: modifying symmetry and stability of a circular oligomer | Descriptor: | TRANSCRIPTION ATTENUATION PROTEIN MTRB, TRYPTOPHAN | Authors: | Bayfield, O.W, Chen, C, Patterson, A.R, Luan, W, Smits, C, Gollnick, P, Antson, A.A. | Deposit date: | 2012-07-12 | Release date: | 2012-09-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Trp RNA-Binding Attenuation Protein: Modifying Symmetry and Stability of a Circular Oligomer. Plos One, 7, 2012
|
|
5EZ4
| 2.11 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) P449M/Y450L double mutant from Staphylococcus aureus in complex with NAD+ and BME-modified Cys289 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Betaine aldehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Halavaty, A.S, Minasov, G, Chen, C, Joo, J.C, Yakunin, A.F, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2015-11-26 | Release date: | 2015-12-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | 2.11 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) P449M/Y450L double mutant from Staphylococcus aureus in complex with NAD+ and BME-modified Cys289 To Be Published
|
|
5EYU
| 1.72 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) P449M point mutant from Staphylococcus aureus in complex with NAD+ and BME-modified Cys289 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Betaine aldehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Halavaty, A.S, Minasov, G, Chen, C, Joo, J.C, Yakunin, A.F, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2015-11-25 | Release date: | 2015-12-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | 1.72 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) P449M point mutant from Staphylococcus aureus in complex with NAD+ and BME-modified Cys289 To Be Published
|
|
4ZWL
| 2.60 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) H448F/Y450L double mutant from Staphylococcus aureus in complex with NAD+ and BME-free Cys289 | Descriptor: | Betaine-aldehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION | Authors: | Halavaty, A.S, Minasov, G, Chen, C, Joo, J.C, Yakunin, A.F, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2015-05-19 | Release date: | 2015-05-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | 2.60 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) H448F/Y450L double mutant from Staphylococcus aureus in complex with NAD+ and BME-free Cys289 To be Published
|
|
7DNU
| mRNA-decapping enzyme g5Rp with inhibitor insp6 complex | Descriptor: | INOSITOL HEXAKISPHOSPHATE, mRNA-decapping protein g5R | Authors: | Yang, Y, Chen, C, Li, L, Li, X.H, Su, D. | Deposit date: | 2020-12-10 | Release date: | 2021-12-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.245 Å) | Cite: | Structural Insight into Molecular Inhibitory Mechanism of InsP 6 on African Swine Fever Virus mRNA-Decapping Enzyme g5Rp. J.Virol., 96, 2022
|
|
7DNT
| mRNA-decapping enzyme g5Rp | Descriptor: | mRNA-decapping protein g5R | Authors: | Yang, Y, Chen, C, Li, L, Li, X.H, Su, D. | Deposit date: | 2020-12-10 | Release date: | 2022-03-09 | Last modified: | 2022-12-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Insight into Molecular Inhibitory Mechanism of InsP 6 on African Swine Fever Virus mRNA-Decapping Enzyme g5Rp. J.Virol., 96, 2022
|
|
5Z0V
| Structural insight into the Zika virus capsid encapsulating the viral genome | Descriptor: | Extracellular solute-binding protein family 1,viral genome protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Li, T, Zhao, Q, Yang, X, Chen, C, Yang, K, Wu, C, Zhang, T, Duan, Y, Xue, X, Mi, K, Ji, X, Wang, Z, Yang, H. | Deposit date: | 2017-12-21 | Release date: | 2018-04-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.913 Å) | Cite: | Structural insight into the Zika virus capsid encapsulating the viral genome. Cell Res., 28, 2018
|
|
5Z0R
| Structural insight into the Zika virus capsid encapsulating the viral genome | Descriptor: | Extracellular solute-binding protein family 1,viral genome protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Li, T, Zhao, Q, Yang, X, Chen, C, Yang, K, Wu, C, Zhang, T, Duan, Y, Xue, X, Mi, K, Ji, X, Wang, Z, Yang, H. | Deposit date: | 2017-12-20 | Release date: | 2018-04-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural insight into the Zika virus capsid encapsulating the viral genome. Cell Res., 28, 2018
|
|
5GWZ
| The structure of Porcine epidemic diarrhea virus main protease in complex with an inhibitor | Descriptor: | N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE, PEDV main protease | Authors: | Wang, F, Chen, C, Yang, K, Liu, X, Liu, H, Xu, Y, Chen, X, Liu, X, Cai, Y, Yang, H. | Deposit date: | 2016-09-14 | Release date: | 2017-03-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.444 Å) | Cite: | Michael Acceptor-Based Peptidomimetic Inhibitor of Main Protease from Porcine Epidemic Diarrhea Virus J. Med. Chem., 60, 2017
|
|