4ZWL

2.60 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) H448F/Y450L double mutant from Staphylococcus aureus in complex with NAD+ and BME-free Cys289

Summary for 4ZWL

Related4MPB 4MPY 4NEA 4NU9 4QTO 4QN2 4Q92 4QJE
DescriptorBetaine-aldehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... (4 entities in total)
Functional Keywordsbetb, structural genomics, nad, niaid, national institute of allergy and infectious diseases, csgid, rossmann fold, center for structural genomics of infectious diseases, oxidoreductase
Biological sourceStaphylococcus aureus (strain COL)
Total number of polymer chains8
Total molecular weight463349.41
Authors
Primary citation
Halavaty, A.S.,Minasov, G.,Chen, C.,Joo, J.C.,Yakunin, A.F.,Anderson, W.F.
2.60 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) H448F/Y450L double mutant from Staphylococcus aureus in complex with NAD+ and BME-free Cys289
To be Published,
Experimental method
X-RAY DIFFRACTION (2.6 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23240.5%0.1%0.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4zwl
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Molmil generated image of 4zwl
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Molmil generated image of 4zwl
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 4zwl
no rotation
Molmil generated image of 4zwl
rotated about x axis by 90°
Molmil generated image of 4zwl
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (4zwl.pdb1.gz [659.7 KB])
Coordinate files for Biological unit (4zwl.pdb2.gz [659.34 KB])