1MXH
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![BU of 1mxh by Molmil](/molmil-images/mine/1mxh) | Crystal Structure of Substrate Complex of Putative Pteridine Reductase 2 (PTR2) from Trypanosoma cruzi | 分子名称: | DIHYDROFOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PTERIDINE REDUCTASE 2 | 著者 | Schormann, N, Pal, B, Senkovich, O, Carson, M, Howard, A, Smith, C, Delucas, L, Chattopadhyay, D. | 登録日 | 2002-10-02 | 公開日 | 2003-10-14 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of Trypanosoma cruzi pteridine reductase 2 in complex with a substrate and an inhibitor. J.Struct.Biol., 152, 2005
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1NX2
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![BU of 1nx2 by Molmil](/molmil-images/mine/1nx2) | Calpain Domain VI | 分子名称: | CALCIUM ION, Calcium-dependent protease, small subunit | 著者 | Todd, B, Moore, D, Deivanayagam, C.C.S, Lin, G.-D, Chattopadhyay, D, Maki, M, Wang, K.K.W, Narayana, S.V.L. | 登録日 | 2003-02-07 | 公開日 | 2003-08-19 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A structural model for the inhibition of calpain by calpastatin: crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor. J.Mol.Biol., 328, 2003
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1NX1
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![BU of 1nx1 by Molmil](/molmil-images/mine/1nx1) | Calpain Domain VI Complexed with Calpastatin Inhibitory Domain C (DIC) | 分子名称: | CALCIUM ION, Calcium-dependent protease, small subunit, ... | 著者 | Todd, B, Moore, D, Deivanayagam, C.C.S, Lin, G.-D, Chattopadhyay, D, Maki, M, Wang, K.K.W, Narayana, S.V.L. | 登録日 | 2003-02-07 | 公開日 | 2003-08-19 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A structural model for the inhibition of calpain by calpastatin: crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor. J.Mol.Biol., 328, 2003
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1NX0
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![BU of 1nx0 by Molmil](/molmil-images/mine/1nx0) | Structure of Calpain Domain 6 in Complex with Calpastatin DIC | 分子名称: | CALCIUM ION, Calcium-dependent protease, small subunit, ... | 著者 | Todd, B, Moore, D, Deivanayagam, C.C.S, Lin, G.-D, Chattopadhyay, D, Maki, M, Wang, K.K.W, Narayana, S.V.L. | 登録日 | 2003-02-07 | 公開日 | 2003-08-19 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A structural model for the inhibition of calpain by calpastatin: crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor. J.Mol.Biol., 328, 2003
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1EE1
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![BU of 1ee1 by Molmil](/molmil-images/mine/1ee1) | CRYSTAL STRUCTURE OF NH3-DEPENDENT NAD+ SYNTHETASE FROM BACILLUS SUBTILIS COMPLEXED WITH ONE MOLECULE ATP, TWO MOLECULES DEAMIDO-NAD+ AND ONE MG2+ ION | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, NH(3)-DEPENDENT NAD(+) SYNTHETASE, ... | 著者 | Devedjiev, Y, Symersky, J, Singh, R, Jedrzejas, M, Brouillette, C, Brouillette, W, Muccio, D, Chattopadhyay, D, Delucas, L. | 登録日 | 2000-01-28 | 公開日 | 2001-06-06 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Stabilization of active-site loops in NH3-dependent NAD+ synthetase from Bacillus subtilis. Acta Crystallogr.,Sect.D, 57, 2001
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3CLB
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![BU of 3clb by Molmil](/molmil-images/mine/3clb) | Structure of bifunctional TcDHFR-TS in complex with TMQ | 分子名称: | 1,2-ETHANEDIOL, DHFR-TS, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Schormann, N, Senkovich, O, Chattopadhyay, D. | 登録日 | 2008-03-18 | 公開日 | 2009-01-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function. Proteins, 73, 2008
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3CL9
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![BU of 3cl9 by Molmil](/molmil-images/mine/3cl9) | Structure of bifunctional TcDHFR-TS in complex with MTX | 分子名称: | 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase (DHFR-TS), ... | 著者 | Schormann, N, Senkovich, O, Chattopadhyay, D. | 登録日 | 2008-03-18 | 公開日 | 2009-01-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function. Proteins, 73, 2008
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3CIF
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![BU of 3cif by Molmil](/molmil-images/mine/3cif) | Crystal Structure of C153S mutant glyceraldehyde 3-phosphate dehydrogenase from Cryptosporidium parvum | 分子名称: | GLYCERALDEHYDE-3-PHOSPHATE, GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase, ... | 著者 | Cook, W.J, Senkovich, O, Chattopadhyay, D. | 登録日 | 2008-03-11 | 公開日 | 2009-03-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | An unexpected phosphate binding site in Glyceraldehyde 3-Phosphate Dehydrogenase: Crystal structures of apo, holo and ternary complex of Cryptosporidium parvum enzyme BMC STRUCT.BIOL., 9, 2009
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1DOJ
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![BU of 1doj by Molmil](/molmil-images/mine/1doj) | Crystal structure of human alpha-thrombin*RWJ-51438 complex at 1.7 A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN, HIRUGEN, ... | 著者 | Recacha, R, Costanzo, M.J, Maryanoff, B.E, Carson, M, DeLucas, L, Chattopadhyay, D. | 登録日 | 1999-12-21 | 公開日 | 2000-11-03 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of human alpha-thrombin complexed with RWJ-51438 at 1.7 A: unusual perturbation of the 60A-60I insertion loop. Acta Crystallogr.,Sect.D, 56, 2000
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4QCA
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![BU of 4qca by Molmil](/molmil-images/mine/4qca) | Crystal structure of Vaccinia virus uracil-DNA glycosylase mutant R167AD4 | 分子名称: | CHLORIDE ION, GLYCEROL, POTASSIUM ION, ... | 著者 | Sartmatova, D, Nash, T, Schormann, N, Nuth, M, Ricciardi, R, Banerjee, S, Chattopadhyay, D. | 登録日 | 2014-05-09 | 公開日 | 2015-05-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystallization and preliminary X-ray diffraction analysis of three recombinant mutants of Vaccinia virus uracil DNA glycosylase. Acta Crystallogr.,Sect.F, 69, 2013
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1KYN
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![BU of 1kyn by Molmil](/molmil-images/mine/1kyn) | Cathepsin-G | 分子名称: | (2-NAPHTHALEN-2-YL-1-NAPHTHALEN-1-YL-2-OXO-ETHYL)-PHOSPHONIC ACID, cathepsin G | 著者 | Greco, M.N, Hawkins, M.J, Powell, E.T, Almond Jr, H.R, Corcoran, T.W, De Garavilla, L, Kauffman, J.A, Recacha, R, Chattopadhyay, D, Andrade-Gordon, P, Maryanoff, B.E. | 登録日 | 2002-02-05 | 公開日 | 2002-05-01 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Nonpeptide inhibitors of cathepsin G: optimization of a novel beta-ketophosphonic acid lead by structure-based drug design. J.Am.Chem.Soc., 124, 2002
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1NC6
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![BU of 1nc6 by Molmil](/molmil-images/mine/1nc6) | Potent, small molecule inhibitors of human mast cell tryptase. Anti-asthmatic action of a dipeptide-based transition state analogue containing benzothiazole ketone | 分子名称: | (2S,4R)-1-ACETYL-N-[(1S)-4-[(AMINOIMINOMETHYL)AMINO]-1-(2-BENZOTHIAZOLYLCARBONYL)BUTYL]-4-HYDROXY-2-PYRROLIDINECARBOXAMIDE, CALCIUM ION, SULFATE ION, ... | 著者 | Costanzo, M.J, Yabut, S.C, Almond Jr, H.R, Andrade-Gordon, P, Corcoran, T.W, de Garavilla, L, Kauffman, J.A, Abraham, W.M, Recacha, R, Chattopadhyay, D, Maryanoff, B.E. | 登録日 | 2002-12-04 | 公開日 | 2003-09-23 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Potent, Small-Molecule Inhibitors of Human Mast Cell Tryptase. Antiasthmatic Action of a Dipeptide-Based Transition-State Analogue Containing a Benzothiazole Ketone. J.Med.Chem., 46, 2003
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1ALV
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![BU of 1alv by Molmil](/molmil-images/mine/1alv) | CALCIUM BOUND DOMAIN VI OF PORCINE CALPAIN | 分子名称: | CALCIUM ION, CALPAIN | 著者 | Narayana, S.V.L, Lin, G, Chattopadhyay, D, Maki, M. | 登録日 | 1997-06-03 | 公開日 | 1998-06-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of calcium bound domain VI of calpain at 1.9 A resolution and its role in enzyme assembly, regulation, and inhibitor binding. Nat.Struct.Biol., 4, 1997
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5V8X
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5UTL
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![BU of 5utl by Molmil](/molmil-images/mine/5utl) | |
1DGM
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![BU of 1dgm by Molmil](/molmil-images/mine/1dgm) | CRYSTAL STRUCTURE OF ADENOSINE KINASE FROM TOXOPLASMA GONDII | 分子名称: | ACETIC ACID, ADENOSINE, ADENOSINE KINASE, ... | 著者 | Cook, W.J, DeLucas, L.J, Chattopadhyay, D. | 登録日 | 1999-11-24 | 公開日 | 2000-11-29 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of adenosine kinase from Toxoplasma gondii at 1.8 A resolution. Protein Sci., 9, 2000
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5UTM
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5V8Y
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![BU of 5v8y by Molmil](/molmil-images/mine/5v8y) | |
1EOU
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![BU of 1eou by Molmil](/molmil-images/mine/1eou) | CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH AN ANTICONVULSANT SUGAR SULFAMATE | 分子名称: | CARBONIC ANHYDRASE II (CA II), SULFAMIC ACID 2,3-O-(1-METHYLETHYLIDENE)-4,5-O-SULFONYL-BETA-FRUCTOPYRANOSE ESTER, ZINC ION | 著者 | Recacha, R, Costanzo, M.J, Maryanoff, B.E, Chattopadhyay, D. | 登録日 | 2000-03-24 | 公開日 | 2002-02-13 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of human carbonic anhydrase II complexed with an anti-convulsant sugar sulphamate. Biochem.J., 361, 2002
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2OL0
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![BU of 2ol0 by Molmil](/molmil-images/mine/2ol0) | High Resolution Crystal Structures of Vaccinia Virus dUTPase | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DEOXYURIDINE-5'-DIPHOSPHATE, ... | 著者 | Schormann, N, Chattopadhyay, D. | 登録日 | 2007-01-18 | 公開日 | 2007-05-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structures of vaccinia virus dUTPase and its nucleotide complexes. Acta Crystallogr.,Sect.D, 63, 2007
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2OWQ
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![BU of 2owq by Molmil](/molmil-images/mine/2owq) | |
2OKB
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![BU of 2okb by Molmil](/molmil-images/mine/2okb) | High Resolution Crystal Structures of Vaccinia Virus dUTPase | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | 著者 | Schormann, N, Chattopadhyay, D. | 登録日 | 2007-01-16 | 公開日 | 2007-05-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structures of vaccinia virus dUTPase and its nucleotide complexes. Acta Crystallogr.,Sect.D, 63, 2007
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2OKD
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2OL1
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![BU of 2ol1 by Molmil](/molmil-images/mine/2ol1) | High Resolution Crystal Structures of Vaccinia Virus dUTPase | 分子名称: | 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, CHLORIDE ION, ... | 著者 | Schormann, N, Chattopadhyay, D. | 登録日 | 2007-01-18 | 公開日 | 2007-05-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structures of vaccinia virus dUTPase and its nucleotide complexes. Acta Crystallogr.,Sect.D, 63, 2007
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2OKE
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![BU of 2oke by Molmil](/molmil-images/mine/2oke) | High Resolution Crystal Structures of Vaccinia Virus dUTPase | 分子名称: | 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, ... | 著者 | Schormann, N, Chattopadhyay, D. | 登録日 | 2007-01-16 | 公開日 | 2007-05-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structures of vaccinia virus dUTPase and its nucleotide complexes. Acta Crystallogr.,Sect.D, 63, 2007
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