1NX0

Structure of Calpain Domain 6 in Complex with Calpastatin DIC

Summary for 1NX0

Entry DOI	10.2210/pdb1nx0/pdb
Related	1NX1 1NX2 1NX3
Descriptor	Calcium-dependent protease, small subunit, Calpastatin, Small molecule inhibitor, ... (5 entities in total)
Functional Keywords	calcium binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Sus scrofa (pig) More
Cellular location	Cytoplasm (By similarity): P04574
Total number of polymer chains	5
Total formula weight	42963.53
Authors	Todd, B.,Moore, D.,Deivanayagam, C.C.S.,Lin, G.-D.,Chattopadhyay, D.,Maki, M.,Wang, K.K.W.,Narayana, S.V.L. (deposition date: 2003-02-07, release date: 2003-08-19, Last modification date: 2024-02-14)
Primary citation	Todd, B.,Moore, D.,Deivanayagam, C.C.S.,Lin, G.-D.,Chattopadhyay, D.,Maki, M.,Wang, K.K.W.,Narayana, S.V.L. A structural model for the inhibition of calpain by calpastatin: crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor. J.Mol.Biol., 328:131-146, 2003 Cited by PubMed: 12684003 DOI: 10.1016/S0022-2836(03)00274-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation