1NX0
Structure of Calpain Domain 6 in Complex with Calpastatin DIC
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Calcium-dependent protease, small subunit | polymer | 173 | 19883.5 | 2 | UniProt (P04574) In PDB | Sus scrofa (pig) | Calpain regulatory subunit, Calcium-activated neutral proteinase, CANP |
2 | C, D | Calpastatin | polymer | 12 | 1241.3 | 2 | UniProt (P49342) UniProt (by SIFTS) (P12675) In PDB | Sus scrofa (pig) | calpain inhibitor |
3 | E | Small molecule inhibitor | polymer | 5 | 473.6 | 1 | |||
4 | A, B | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
5 | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence modifications
C, D: 601 - 612 (UniProt: P49342)
PDB | External Database | Details |
---|---|---|
Ser 612 | Cys 241 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 42723.1 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 240.5 | |
All* | Total formula weight | 42963.5 |