1DOJ
Crystal structure of human alpha-thrombin*RWJ-51438 complex at 1.7 A
Summary for 1DOJ
Entry DOI | 10.2210/pdb1doj/pdb |
Related | 1abj |
Related PRD ID | PRD_000623 |
Descriptor | ALPHA-THROMBIN, HIRUGEN, N-methyl-D-phenylalanyl-N-{(1S)-4-carbamimidamido-1-[(6-carboxy-1,3-benzothiazol-2-yl)carbonyl]butyl}-L-prolinamide, ... (6 entities in total) |
Functional Keywords | thrombin, serine protease, enzyme inhibition, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 36211.14 |
Authors | Recacha, R.,Costanzo, M.J.,Maryanoff, B.E.,Carson, M.,DeLucas, L.,Chattopadhyay, D. (deposition date: 1999-12-21, release date: 2000-11-03, Last modification date: 2024-03-13) |
Primary citation | Recacha, R.,Costanzo, M.J.,Maryanoff, B.E.,Carson, M.,DeLucas, L.,Chattopadhyay, D. Structure of human alpha-thrombin complexed with RWJ-51438 at 1.7 A: unusual perturbation of the 60A-60I insertion loop. Acta Crystallogr.,Sect.D, 56:1395-1400, 2000 Cited by PubMed: 11053836DOI: 10.1107/S0907444900010763 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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