6URF
 
 | | Malic enzyme from Mycobacterium tuberculosis | | 分子名称: | GLYCEROL, NAD-dependent malic enzyme | | 著者 | Cuthbert, B.J, Burley, K.H, Goulding, C.W, Mathews, E.I, Beste, D.J. | | 登録日 | 2019-10-23 | | 公開日 | 2020-10-28 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structural and Molecular Dynamics of Mycobacterium tuberculosis Malic Enzyme, a Potential Anti-TB Drug Target.
Acs Infect Dis., 7, 2021
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7T4O
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7T4P
 | | CryoEM structure of Methylococcus capsulatus (Bath) pMMO treated with potassium cyanide and copper in a native lipid nanodisc at 3.62 Angstrom resolution | | 分子名称: | 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dihexanoyl-sn-glycero-3-phosphocholine, Ammonia monooxygenase/methane monooxygenase, ... | | 著者 | Koo, C.W, Rosenzweig, A.C. | | 登録日 | 2021-12-10 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | | 主引用文献 | Recovery of particulate methane monooxygenase structure and activity in a lipid bilayer.
Science, 375, 2022
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6VEK
 | | Contact-dependent growth inhibition toxin-immunity protein complex from from E. coli 3006, full-length | | 分子名称: | contact-dependent immunity protein CdiI, contact-dependent toxin CdiA | | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-01-02 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Contact-dependent growth inhibition toxin-immunity protein complex from from E. coli 3006, full-length
To Be Published
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7AEA
 | | Cryo-EM structure of human RNA Polymerase III elongation complex 2 | | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | | 著者 | Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. | | 登録日 | 2020-09-17 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states.
Nat.Struct.Mol.Biol., 28, 2021
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7AE3
 | | Cryo-EM structure of human RNA Polymerase III elongation complex 3 | | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | | 著者 | Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. | | 登録日 | 2020-09-17 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states.
Nat.Struct.Mol.Biol., 28, 2021
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6VMY
 | | Structure of the B. subtilis cobalamin riboswitch | | 分子名称: | Adenosylcobalamin, B. subtilis cobalamin riboswitch, COBALT HEXAMMINE(III), ... | | 著者 | Chan, C.W, Mondragon, A. | | 登録日 | 2020-01-28 | | 公開日 | 2020-06-10 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Crystal structure of an atypical cobalamin riboswitch reveals RNA structural adaptability as basis for promiscuous ligand binding.
Nucleic Acids Res., 48, 2020
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7UBZ
 | | Chymotrypsin digested toxin/immunity complex for a T6SS lipase effector from E. cloacae | | 分子名称: | Ankyrin repeat domain-containing protein, CITRATE ANION, GLYCEROL, ... | | 著者 | Cuthbert, B.J, Jensen, S.J, Goulding, C.W, Hayes, C.S. | | 登録日 | 2022-03-15 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Toxin/immunity complex for a T6SS lipase effector from E. cloacae
To Be Published
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7UQ0
 | | Putative periplasmic iron siderophore binding protein FecB (Rv3044) from Mycobacterium tuberculosis | | 分子名称: | CITRIC ACID, GLYCEROL, PENTAETHYLENE GLYCOL, ... | | 著者 | Chao, A, Cuthbert, B.J, Goulding, C.W. | | 登録日 | 2022-04-18 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Differentiating the roles of Mycobacterium tuberculosis substrate binding proteins, FecB and FecB2, in iron uptake.
Plos Pathog., 19, 2023
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6XL0
 | | Caulobacter crescentus FljK filament | | 分子名称: | Flagellin | | 著者 | Montemayor, E.J, Ploscariu, N.T, Sanchez, J.C, Parrell, D, Dillard, R.S, Shebelut, C.W, Ke, Z, Guerrero-Ferreira, R.C, Wright, E.R. | | 登録日 | 2020-06-27 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Flagellar Structures from the Bacterium Caulobacter crescentus and Implications for Phage phi CbK Predation of Multiflagellin Bacteria
J.Bacteriol., 203, 2021
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6XKY
 | | Caulobacter crescentus FljK filament, straightened | | 分子名称: | Flagellin | | 著者 | Montemayor, E.J, Ploscariu, N.T, Sanchez, J.C, Parrell, D, Dillard, R.S, Shebelut, C.W, Ke, Z, Guerrero-Ferreira, R.C, Wright, E.R. | | 登録日 | 2020-06-27 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Flagellar Structures from the Bacterium Caulobacter crescentus and Implications for Phage phi CbK Predation of Multiflagellin Bacteria
J.Bacteriol., 203, 2021
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1WAY
 | | Active site thrombin inhibitors | | 分子名称: | 4-[3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-YL]PIPERIDINE, DIMETHYL SULFOXIDE, HIRUGEN, ... | | 著者 | Hartshorn, M.J, Murray, C.W, Cleasby, A, Frederickson, M, Tickle, I.J, Jhoti, H. | | 登録日 | 2004-10-28 | | 公開日 | 2005-01-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Fragment-Based Lead Discovery Using X-Ray Crystallography
J.Med.Chem., 48, 2005
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1WBG
 | | Active site thrombin inhibitors | | 分子名称: | 3-(4-CHLOROPHENYL)-5-(METHYLTHIO)-4H-1,2,4-TRIAZOLE, DIMETHYL SULFOXIDE, HIRUGEN, ... | | 著者 | Hartshorn, M.J, Murray, C.W, Cleasby, A, Frederickson, M, Tickle, I.J, Jhoti, H. | | 登録日 | 2004-11-01 | | 公開日 | 2005-01-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Fragment-Based Lead Discovery Using X-Ray Crystallography
J.Med.Chem., 48, 2005
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1W9C
 | | Proteolytic fragment of CRM1 spanning six C-terminal HEAT repeats | | 分子名称: | CRM1 PROTEIN | | 著者 | Petosa, C, Schoehn, G, Askjaer, P, Bauer, U, Moulin, M, Steuerwald, U, Soler-Lopez, M, Baudin, F, Mattaj, I.W, Muller, C.W. | | 登録日 | 2004-10-08 | | 公開日 | 2004-12-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Architecture of Crm1-Exportin 1 Suggests How Cooperativity is Achieved During Formation of a Nuclear Export Complex
Mol.Cell, 16, 2004
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1WAX
 | | Protein tyrosine phosphatase 1B with active site inhibitor | | 分子名称: | MAGNESIUM ION, PROTEIN-TYROSINE PHOSPHATASE, [[4-(AMINOMETHYL)PHENYL]AMINO]OXO-ACETIC ACID, | | 著者 | Hartshorn, M.J, Murray, C.W, Cleasby, A, Frederickson, M, Tickle, I.J, Jhoti, H. | | 登録日 | 2004-10-28 | | 公開日 | 2005-01-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Fragment-Based Lead Discovery Using X-Ray Crystallography
J.Med.Chem., 48, 2005
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1W50
 | | Apo Structure of BACE (Beta Secretase) | | 分子名称: | BETA-SECRETASE 1, IODIDE ION | | 著者 | Patel, S, Vuillard, L, Cleasby, A, Murray, C.W, Yon, J. | | 登録日 | 2004-08-04 | | 公開日 | 2004-09-23 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Apo and Inhibitor Complex Structures of Bace (Beta-Secretase)
J.Mol.Biol., 343, 2004
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1W51
 | | BACE (Beta Secretase) in complex with a nanomolar non-peptidic inhibitor | | 分子名称: | 3-[({(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}AMINO)(HYDROXY)METHYL]-N,N-DIPROPYLBENZAMIDE, BETA-SECRETASE 1, IODIDE ION | | 著者 | Patel, S, Vuillard, L, Cleasby, A, Murray, C.W, Yon, J. | | 登録日 | 2004-08-04 | | 公開日 | 2004-09-23 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Apo and Inhibitor Complex Structures of Bace (Beta-Secretase)
J.Mol.Biol., 343, 2004
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1VQB
 | | GENE V PROTEIN (SINGLE-STRANDED DNA BINDING PROTEIN) | | 分子名称: | GENE V PROTEIN | | 著者 | Skinner, M.M, Zhang, H, Leschnitzer, D.H, Guan, Y, Bellamy, H, Sweet, R.M, Gray, C.W, Konings, R.N.H, Wang, A.H.-J, Terwilliger, T.C. | | 登録日 | 1996-08-14 | | 公開日 | 1997-02-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of the gene V protein of bacteriophage f1 determined by multiwavelength x-ray diffraction on the selenomethionyl protein.
Proc.Natl.Acad.Sci.USA, 91, 1994
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1FQJ
 | | CRYSTAL STRUCTURE OF THE HETEROTRIMERIC COMPLEX OF THE RGS DOMAIN OF RGS9, THE GAMMA SUBUNIT OF PHOSPHODIESTERASE AND THE GT/I1 CHIMERA ALPHA SUBUNIT [(RGS9)-(PDEGAMMA)-(GT/I1ALPHA)-(GDP)-(ALF4-)-(MG2+)] | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(t) subunit alpha-1,Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(t) subunit alpha-1, MAGNESIUM ION, ... | | 著者 | Slep, K.C, Kercher, M.A, He, W, Cowan, C.W, Wensel, T.G, Sigler, P.B. | | 登録日 | 2000-09-05 | | 公開日 | 2001-02-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.
Nature, 409, 2001
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1FQK
 | | CRYSTAL STRUCTURE OF THE HETERODIMERIC COMPLEX OF THE RGS DOMAIN OF RGS9, AND THE GT/I1 CHIMERA ALPHA SUBUNIT [(RGS9)-(GT/I1ALPHA)-(GDP)-(ALF4-)-(MG2+)] | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(t) subunit alpha-1,Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(t) subunit alpha-1, MAGNESIUM ION, ... | | 著者 | Slep, K.C, Kercher, M.A, He, W, Cowan, C.W, Wensel, T.G, Sigler, P.B. | | 登録日 | 2000-09-05 | | 公開日 | 2001-02-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.
Nature, 409, 2001
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1FQI
 | | RGS9 RGS DOMAIN | | 分子名称: | REGULATOR OF G-PROTEIN SIGNALING 9 | | 著者 | Slep, K.C, Kercher, M.A, He, W, Cowan, C.W, Wensel, T.G, Sigler, P.B. | | 登録日 | 2000-09-05 | | 公開日 | 2001-02-28 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.
Nature, 409, 2001
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2GVA
 | | REFINED SOLUTION STRUCTURE OF THE TYR 41--> HIS MUTANT OF THE M13 GENE V PROTEIN. A COMPARISON WITH THE CRYSTAL STRUCTURE | | 分子名称: | GENE V PROTEIN | | 著者 | Folkers, P.J.M, Nilges, M, Folmer, R.H.A, Prompers, J.J, Konings, R.N.H, Hilbers, C.W. | | 登録日 | 1995-07-27 | | 公開日 | 1995-10-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Refined solution structure of the Tyr41-->His mutant of the M13 gene V protein. A comparison with the crystal structure.
Eur.J.Biochem., 232, 1995
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2GVB
 | | REFINED SOLUTION STRUCTURE OF THE TYR 41--> HIS MUTANT OF THE M13 GENE V PROTEIN. A COMPARISON WITH THE CRYSTAL STRUCTURE | | 分子名称: | GENE V PROTEIN | | 著者 | Folkers, P.J.M, Nilges, M, Folmer, R.H.A, Prompers, J.J, Konings, R.N.H, Hilbers, C.W. | | 登録日 | 1995-07-27 | | 公開日 | 1995-10-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Refined solution structure of the Tyr41-->His mutant of the M13 gene V protein. A comparison with the crystal structure.
Eur.J.Biochem., 232, 1995
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1H95
 | | Solution structure of the single-stranded DNA-binding Cold Shock Domain (CSD) of human Y-box protein 1 (YB1) determined by NMR (10 lowest energy structures) | | 分子名称: | Y-BOX BINDING PROTEIN | | 著者 | Kloks, C.P.A.M, Spronk, C.A.E.M, Hoffmann, A, Vuister, G.W, Grzesiek, S, Hilbers, C.W. | | 登録日 | 2001-02-23 | | 公開日 | 2002-02-21 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Solution Structure and DNA-Binding Properties of the Cold-Shock Domain of the Human Y-Box Protein Yb-1.
J.Mol.Biol., 316, 2002
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1GZ4
 | | molecular mechanism of the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, FUMARIC ACID, MANGANESE (II) ION, ... | | 著者 | Yang, Z, Lanks, C.W, Tong, L. | | 登録日 | 2002-05-15 | | 公開日 | 2002-07-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Molecular Mechanism for the Regulation of Human Mitochondrial Nad(P)(+)-Dependent Malic Enzyme by ATP and Fumarate
Structure, 10, 2002
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