6URF

Malic enzyme from Mycobacterium tuberculosis

Summary for 6URF

• Entry DOI: 10.2210/pdb6urf/pdb
• Descriptor: NAD-dependent malic enzyme, GLYCEROL (3 entities in total)
• Functional Keywords: malic enzyme, fatty acid synthesis, glucose metabolism, cytosolic protein, oxidoreductase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 4
• Total formula weight: 248624.78

Authors

Cuthbert, B.J.,Burley, K.H.,Goulding, C.W.,Mathews, E.I.,Beste, D.J. (deposition date: 2019-10-23, release date: 2020-10-28, Last modification date: 2023-10-11)

• Primary citation: Burley, K.H.,Cuthbert, B.J.,Basu, P.,Newcombe, J.,Irimpan, E.M.,Quechol, R.,Foik, I.P.,Mobley, D.L.,Beste, D.J.V.,Goulding, C.W.; Structural and Molecular Dynamics of Mycobacterium tuberculosis Malic Enzyme, a Potential Anti-TB Drug Target.; Acs Infect Dis., 7:174-188, 2021; PubMed: 33356117; DOI: 10.1021/acsinfecdis.0c00735

Experimental method

X-RAY DIFFRACTION (3.6 Å)