1FQK

CRYSTAL STRUCTURE OF THE HETERODIMERIC COMPLEX OF THE RGS DOMAIN OF RGS9, AND THE GT/I1 CHIMERA ALPHA SUBUNIT [(RGS9)-(GT/I1ALPHA)-(GDP)-(ALF4-)-(MG2+)]

Summary for 1FQK

Related1FQJ 1fqi
DescriptorGuanine nucleotide-binding protein G(t) subunit alpha-1,Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(t) subunit alpha-1, Regulator of G-protein signaling 9, MAGNESIUM ION, ... (6 entities in total)
Functional Keywordsrgs9, transducin, g protein, phototransduction, rod, rgs, gap, signaling protein
Biological sourceBos taurus (Bovine)
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Cellular locationMembrane; Peripheral membrane protein O46469
Total number of polymer chains4
Total molecular weight110702.63
Authors
Slep, K.C.,Kercher, M.A.,He, W.,Cowan, C.W.,Wensel, T.G.,Sigler, P.B. (deposition date: 2000-09-05, release date: 2001-02-28, Last modification date: 2017-06-28)
Primary citation
Slep, K.C.,Kercher, M.A.,He, W.,Cowan, C.W.,Wensel, T.G.,Sigler, P.B.
Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.
Nature, 409:1071-1077, 2001
PubMed: 11234020 (PDB entries with the same primary citation)
DOI: 10.1038/35059138
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers12 0.3% 1.8% 4.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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171588
PDB entries from 2020-11-25