1FQJ

CRYSTAL STRUCTURE OF THE HETEROTRIMERIC COMPLEX OF THE RGS DOMAIN OF RGS9, THE GAMMA SUBUNIT OF PHOSPHODIESTERASE AND THE GT/I1 CHIMERA ALPHA SUBUNIT [(RGS9)-(PDEGAMMA)-(GT/I1ALPHA)-(GDP)-(ALF4-)-(MG2+)]

Summary for 1FQJ

• Entry DOI: 10.2210/pdb1fqj/pdb
• Related: 1FQI 1FQK
• Descriptor: Guanine nucleotide-binding protein G(t) subunit alpha-1,Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(t) subunit alpha-1, Regulator of G-protein signaling 9, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ... (7 entities in total)
• Functional Keywords: rgs9, transducin, effector, pdegamma, g protein, phototransduction, rod, rgs, phosphodiesterase, gap, signaling protein
• Biological source: Bos taurus (Bovine); More
• Cellular location: Membrane; Peripheral membrane protein: O46469
• Total number of polymer chains: 5
• Total formula weight: 115261.72

Authors

Slep, K.C.,Kercher, M.A.,He, W.,Cowan, C.W.,Wensel, T.G.,Sigler, P.B. (deposition date: 2000-09-05, release date: 2001-02-28, Last modification date: 2024-02-07)

• Primary citation: Slep, K.C.,Kercher, M.A.,He, W.,Cowan, C.W.,Wensel, T.G.,Sigler, P.B.; Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.; Nature, 409:1071-1077, 2001; PubMed: 11234020; DOI: 10.1038/35059138

Experimental method

X-RAY DIFFRACTION (2.02 Å)