1FQJ

CRYSTAL STRUCTURE OF THE HETEROTRIMERIC COMPLEX OF THE RGS DOMAIN OF RGS9, THE GAMMA SUBUNIT OF PHOSPHODIESTERASE AND THE GT/I1 CHIMERA ALPHA SUBUNIT [(RGS9)-(PDEGAMMA)-(GT/I1ALPHA)-(GDP)-(ALF4-)-(MG2+)]

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	Guanine nucleotide-binding protein G(t) subunit alpha-1,Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(t) subunit alpha-1	polymer	325	37361.7	2	UniProt (P04695) UniProt (P10824) Pfam (PF00503) In PDB	Bos taurus (Bovine)	Transducin alpha-1 chain,Adenylate cyclase-inhibiting G alpha protein,Transducin alpha-1 chain
2	B, E	Regulator of G-protein signaling 9	polymer	147	17419.2	2	UniProt (O46469) Pfam (PF00615) In PDB	Bos taurus (Bovine)	RGS9
3	C	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	polymer	42	4559.1	1	UniProt (P04972) Pfam (PF04868) In PDB	Bos taurus (Bovine)	GMP-PDE gamma
4	A, D	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	A, D	TETRAFLUOROALUMINATE ION	non-polymer		103.0	2	Chemie (ALF)
6	A, D	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)
7		water	water		18.0	356	Chemie (HOH)

Sequence modifications

A, D: 26 - 215 (UniProt: P04695)
A, D: 216 - 294 (UniProt: P10824)
A, D: 295 - 350 (UniProt: P04695)

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	114120.8
Non-Polymers*	Number of molecules	6
	Total formula weight	1141.0
All*	Total formula weight	115261.7

*Water molecules are not included.