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CRYSTAL STRUCTURE OF THE HETEROTRIMERIC COMPLEX OF THE RGS DOMAIN OF RGS9, THE GAMMA SUBUNIT OF PHOSPHODIESTERASE AND THE GT/I1 CHIMERA ALPHA SUBUNIT [(RGS9)-(PDEGAMMA)-(GT/I1ALPHA)-(GDP)-(ALF4-)-(MG2+)]
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Guanine nucleotide-binding protein G(t) subunit alpha-1,Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(t) subunit alpha-1 | polymer | 325 | 37361.7 | 2 | UniProt (P04695) UniProt (P10824) Pfam (PF00503) | Bos taurus (Bovine) | Transducin alpha-1 chain,Adenylate cyclase-inhibiting G alpha protein,Transducin alpha-1 chain |
| 2 | B, E (B, E) | Regulator of G-protein signaling 9 | polymer | 147 | 17419.2 | 2 | UniProt (O46469) Pfam (PF00615) | Bos taurus (Bovine) | RGS9 |
| 3 | C (C) | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | polymer | 42 | 4559.1 | 1 | UniProt (P04972) Pfam (PF04868) | Bos taurus (Bovine) | GMP-PDE gamma |
| 4 | F, I (A, D) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | G, J (A, D) | TETRAFLUOROALUMINATE ION | non-polymer | 103.0 | 2 | Chemie (ALF) | |||
| 6 | H, K (A, D) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 7 | L, M, N, O, P (A, B, C, D, E) | water | water | 18.0 | 356 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 114120.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1141.0 | |
| All* | Total formula weight | 115261.7 |
