1FQJ

CRYSTAL STRUCTURE OF THE HETEROTRIMERIC COMPLEX OF THE RGS DOMAIN OF RGS9, THE GAMMA SUBUNIT OF PHOSPHODIESTERASE AND THE GT/I1 CHIMERA ALPHA SUBUNIT [(RGS9)-(PDEGAMMA)-(GT/I1ALPHA)-(GDP)-(ALF4-)-(MG2+)]

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	Guanine nucleotide-binding protein G(t) subunit alpha-1,Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(t) subunit alpha-1	polymer	325	37361.7	2	UniProt (P04695) UniProt (P10824) Pfam (PF00503)	Bos taurus (Bovine)	Transducin alpha-1 chain,Adenylate cyclase-inhibiting G alpha protein,Transducin alpha-1 chain
2	B, E (B, E)	Regulator of G-protein signaling 9	polymer	147	17419.2	2	UniProt (O46469) Pfam (PF00615)	Bos taurus (Bovine)	RGS9
3	C (C)	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	polymer	42	4559.1	1	UniProt (P04972) Pfam (PF04868)	Bos taurus (Bovine)	GMP-PDE gamma
4	F, I (A, D)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG) PubChem (888)
5	G, J (A, D)	TETRAFLUOROALUMINATE ION	non-polymer		103.0	2	Chemie (ALF) PubChem (5311325)
6	H, K (A, D)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537)
7	L, M, N, O, P (A, B, C, D, E)	water	water		18.0	356	Chemie (HOH)

Sequence modifications

A, D: 26 - 215 (UniProt: P04695)
A, D: 216 - 294 (UniProt: P10824)
A, D: 295 - 350 (UniProt: P04695)

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	114120.8
Non-Polymers*	Number of molecules	6
	Total formula weight	1141.0
All*	Total formula weight	115261.7

*Water molecules are not included.