4V4Q
| Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Schuwirth, B.S, Borovinskaya, M.A, Hau, C.W, Zhang, W, Vila-Sanjurjo, A, Holton, J.M, Cate, J.H.D. | 登録日 | 2005-08-30 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | 主引用文献 | Structures of the bacterial ribosome at 3.5 A resolution. Science, 310, 2005
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5T86
| Crystal structure of CDI complex from E. coli A0 34/86 | 分子名称: | ACETATE ION, CdiA toxin, CdiI immunity protein | 著者 | Michalska, K, Stols, L, Jedrzejczak, R, Hayes, C.S, Goulding, C.W, Joachimiak, A, Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Midwest Center for Structural Genomics (MCSG) | 登録日 | 2016-09-06 | 公開日 | 2017-09-13 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of CDI complex from E. coli A0 34/86 To Be Published
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1HIP
| TWO-ANGSTROM CRYSTAL STRUCTURE OF OXIDIZED CHROMATIUM HIGH POTENTIAL IRON PROTEIN | 分子名称: | HIGH POTENTIAL IRON PROTEIN, IRON/SULFUR CLUSTER | 著者 | Carterjunior, C.W, Kraut, J, Freer, S.T, Xuong, N.-H, Alden, R.A, Bartsch, R.G. | 登録日 | 1975-04-01 | 公開日 | 1976-11-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Two-Angstrom crystal structure of oxidized Chromatium high potential iron protein. J.Biol.Chem., 249, 1974
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1QXK
| Monoacid-Based, Cell Permeable, Selective Inhibitors of Protein Tyrosine Phosphatase 1B | 分子名称: | 2-{4-[2-ACETYLAMINO-3-(4-CARBOXYMETHOXY-3-HYDROXY-PHENYL)-PROPIONYLAMINO]-BUTOXY}-6-HYDROXY-BENZOIC ACID METHYL ESTER, Protein-tyrosine phosphatase, non-receptor type 1 | 著者 | Xin, Z, Liu, G, Abad-Zapatero, C, Pei, Z, Szczepankiewick, B.G, Li, X, Zhang, T, Hutchins, C.W, Hajduk, P.J, Ballaron, S.J, Stashko, M.A, Lubben, T.H, Trevillyan, J.M, Jirousek, M.R. | 登録日 | 2003-09-08 | 公開日 | 2003-10-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Identification of a Monoacid-Based, Cell Permeable, Selective
Inhibitor of Protein Tyrosine Phosphatase 1B BIOORG.MED.CHEM.LETT., 13, 2003
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7XH9
| Crystal structure of a dimeric interlocked parallel G-quadruplex | 分子名称: | DNA (5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*CP*GP*GP*TP*GP*GP*GP*T)-3'), POTASSIUM ION, STRONTIUM ION | 著者 | Ngo, K.H, Liew, C.W, Lattmann, S, Winnerdy, F.R, Phan, A.T. | 登録日 | 2022-04-07 | 公開日 | 2023-02-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Crystal structures of an HIV-1 integrase aptamer: Formation of a water-mediated A.G.G.G.G pentad in an interlocked G-quadruplex. Biochem.Biophys.Res.Commun., 613, 2022
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7XHD
| Crystal structure of a dimeric interlocked parallel G-quadruplex | 分子名称: | DNA (5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*TP*GP*GP*GP*T)-3'), POTASSIUM ION | 著者 | Ngo, K.H, Liew, C.W, Lattmann, S, Winnerdy, F.R, Phan, A.T. | 登録日 | 2022-04-08 | 公開日 | 2023-02-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Crystal structures of an HIV-1 integrase aptamer: Formation of a water-mediated A•G•G•G•G pentad in an interlocked G-quadruplex. Biochem.Biophys.Res.Commun., 613, 2022
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7XIE
| Crystal structure of a dimeric interlocked parallel G-quadruplex | 分子名称: | DNA (5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*GP*GP*GP*TP*GP*GP*GP*T)-3'), POTASSIUM ION | 著者 | Ngo, K.H, Liew, C.W, Lattmann, S, Winnerdy, F.R, Phan, A.T. | 登録日 | 2022-04-13 | 公開日 | 2023-02-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Crystal structures of an HIV-1 integrase aptamer: Formation of a water-mediated A•G•G•G•G pentad in an interlocked G-quadruplex. Biochem.Biophys.Res.Commun., 613, 2022
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6TUT
| Cryo-EM structure of the RNA Polymerase III-Maf1 complex | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | 著者 | Vorlaender, M.K, Hagen, W.J.H, Mueller, C.W. | 登録日 | 2020-01-08 | 公開日 | 2020-02-19 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Structural basis for RNA polymerase III transcription repression by Maf1. Nat.Struct.Mol.Biol., 27, 2020
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2PX6
| Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat | 分子名称: | (2S,3S,5S)-5-[(N-FORMYL-L-LEUCYL)OXY]-2-HEXYL-3-HYDROXYHEXADECANOIC ACID, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Thioesterase domain | 著者 | Pemble IV, C.W, Johnson, L.C, Kridel, S.J, Lowther, W.T. | 登録日 | 2007-05-14 | 公開日 | 2007-07-10 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat. Nat.Struct.Mol.Biol., 14, 2007
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5WYQ
| Crystal Structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa | 分子名称: | S-ADENOSYLMETHIONINE, tRNA (guanine-N(1)-)-methyltransferase | 著者 | Jaroensuk, J, Liew, C.W, Atichartpongkul, S, Chionh, Y.H, Wong, Y.H, Zhong, W, McBee, M.E, Maenpuen, S, Prestwich, E.G, DeMott, M.S, Mongkolsuk, S, Dedon, P.C, Lescar, J, Fuangthong, M, Chaiyen, P. | 登録日 | 2017-01-15 | 公開日 | 2017-12-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD fromPseudomonas aeruginosa. Rna, 2019
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2PYO
| Drosophila nucleosome core | 分子名称: | CHLORIDE ION, DNA (147-MER), Histone H2A, ... | 著者 | Clapier, C.R, Petosa, C, Mueller, C.W. | 登録日 | 2007-05-16 | 公開日 | 2007-11-06 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Structure of the Drosophila nucleosome core particle highlights evolutionary constraints on the H2A-H2B histone dimer. Proteins, 71, 2007
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2PVR
| Crystal structure of the catalytic subunit of protein kinase CK2 (C-terminal deletion mutant 1-335) in complex with two sulfate ions | 分子名称: | Casein kinase II subunit alpha, catalytic subunit, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Niefind, K, Yde, C.W, Ermakova, I, Issinger, O.-G. | 登録日 | 2007-05-10 | 公開日 | 2007-06-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.605 Å) | 主引用文献 | Evolved to Be Active: Sulfate Ions Define Substrate Recognition Sites of CK2alpha and Emphasise its Exceptional Role within the CMGC Family of Eukaryotic Protein Kinases J.Mol.Biol., 370, 2007
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5WYR
| Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa | 分子名称: | SINEFUNGIN, tRNA (guanine-N(1)-)-methyltransferase | 著者 | Jaroensuk, J, Liew, C.W, Atichartpongkul, S, Chionh, Y.H, Wong, Y.H, Zhong, W.H, McBee, M.E, Thongdee, N, Prestwich, E.G, DeMott, M.S, Mongkolsuk, S, Dedon, P.C, Lescar, J, Fuangthong, M. | 登録日 | 2017-01-15 | 公開日 | 2017-12-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD fromPseudomonas aeruginosa. Rna, 2019
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3ZYU
| Crystal Structure of the first bromodomain of human BRD4 in complex with I-BET151(GSK1210151A) | 分子名称: | 1,2-ETHANEDIOL, 7-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-8-METHOXY-1-[(1R)-1-(PYRIDIN-2-YL)ETHYL]-1H,2H,3H-IMIDAZO[4,5-C]QUINOLIN-2-ONE, BROMODOMAIN-CONTAINING PROTEIN 4 | 著者 | Chung, C.W, Mirguet, O. | 登録日 | 2011-08-25 | 公開日 | 2011-11-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Inhibition of Bet Recruitment to Chromatin as an Effective Treatment for Mll-Fusion Leukaemia. Nature, 478, 2011
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4N8I
| M31G mutant, RipA structure | 分子名称: | 4-hydroxybutyrate coenzyme A transferase, ACETATE ION, COENZYME A | 著者 | Torres, R, Goulding, C.W. | 登録日 | 2013-10-17 | 公開日 | 2014-04-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.011 Å) | 主引用文献 | Structural snapshots along the reaction pathway of Yersinia pestis RipA, a putative butyryl-CoA transferase. Acta Crystallogr.,Sect.D, 70, 2014
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5WT7
| FAS1-IV domain of Human Periostin | 分子名称: | Periostin | 著者 | Yun, H, Lee, C.W. | 登録日 | 2016-12-09 | 公開日 | 2017-12-13 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | 1H,13C, and 15N resonance assignments of FAS1-IV domain of human periostin, a component of extracellular matrix proteins. Biomol NMR Assign, 12, 2018
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4A9J
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4N8K
| E249A mutant, RipA structure | 分子名称: | Putative 4-hydroxybutyrate coenzyme A transferase | 著者 | Torres, R, Goulding, C.W. | 登録日 | 2013-10-17 | 公開日 | 2014-04-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural snapshots along the reaction pathway of Yersinia pestis RipA, a putative butyryl-CoA transferase. Acta Crystallogr.,Sect.D, 70, 2014
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3BO0
| Ribosome-SecY complex | 分子名称: | 23S RIBOSOMAL RNA, PREPROTEIN TRANSLOCASE SecE SUBUNIT, PREPROTEIN TRANSLOCASE SecY SUBUNIT, ... | 著者 | Akey, C.W, Menetret, J.F. | 登録日 | 2007-12-15 | 公開日 | 2008-12-09 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (9.6 Å) | 主引用文献 | Ribosome binding of a single copy of the SecY complex: implications for protein translocation Mol.Cell, 28, 2007
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3BXL
| Crystal structure of the R-type calcium channeL (CaV2.3) IQ domain and CA2+calmodulin complex | 分子名称: | CALCIUM ION, Calmodulin, SULFATE ION, ... | 著者 | Mori, M.X, Vander Kooi, C.W, Leahy, D.J, Yue, D.T. | 登録日 | 2008-01-14 | 公開日 | 2008-03-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the CaV2 IQ domain in complex with Ca2+/calmodulin To be Published
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3PHP
| STRUCTURE OF THE 3' HAIRPIN OF THE TYMV PSEUDOKNOT: PREFORMATION IN RNA FOLDING | 分子名称: | RNA (5'-R(*GP*GP*UP*UP*CP*CP*GP*AP*GP*GP*GP*UP*CP*AP*UP*CP*GP*GP*AP*AP*CP*CP*A) -3') | 著者 | Kolk, M.H, Van Der Graaf, M, Wijmenga, S.S, Pleij, C.W.A, Heus, H.A, Hilbers, C.W. | 登録日 | 1998-10-13 | 公開日 | 1998-10-21 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the 3'-hairpin of the TYMV pseudoknot: preformation in RNA folding. EMBO J., 17, 1998
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1GTQ
| 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE | 分子名称: | 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE, ZINC ION | 著者 | Nar, H, Huber, R, Heizmann, C.W, Thoeny, B, Buergisser, D. | 登録日 | 1995-09-16 | 公開日 | 1996-04-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Three-dimensional structure of 6-pyruvoyl tetrahydropterin synthase, an enzyme involved in tetrahydrobiopterin biosynthesis. EMBO J., 13, 1994
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3KCW
| Crystal structure of Ganoderma fungal immunomodulatory protein, GMI | 分子名称: | immunomodulatory protein | 著者 | Hsu, M.F, Wang, A.H.J, Yang, C.S, Huang, C.T, Hseu, R.S, Lin, C.W, Wu, M.Y, Huang, C.S, Fu, H.Y. | 登録日 | 2009-10-22 | 公開日 | 2010-11-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Single cysteine replacement at Leu6 increase the potent and thermostability in Ganoderma fungal immunomodulatory proteins To be Published
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3KVF
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7LJP
| Structure of Thermotoga maritima SmpB | 分子名称: | 1,4-DIETHYLENE DIOXIDE, GLYCEROL, SULFATE ION, ... | 著者 | Chan, C.W, Mondragon, A. | 登録日 | 2021-01-29 | 公開日 | 2022-02-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of Thermotoga maritima SmpB reveals its C-terminal tail domain in a helical conformation mimicking that of a ribosome-bound state To Be Published
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