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PDB: 2226 件

4V4Q
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BU of 4v4q by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Schuwirth, B.S, Borovinskaya, M.A, Hau, C.W, Zhang, W, Vila-Sanjurjo, A, Holton, J.M, Cate, J.H.D.
登録日2005-08-30
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.46 Å)
主引用文献Structures of the bacterial ribosome at 3.5 A resolution.
Science, 310, 2005
5T86
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BU of 5t86 by Molmil
Crystal structure of CDI complex from E. coli A0 34/86
分子名称: ACETATE ION, CdiA toxin, CdiI immunity protein
著者Michalska, K, Stols, L, Jedrzejczak, R, Hayes, C.S, Goulding, C.W, Joachimiak, A, Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Midwest Center for Structural Genomics (MCSG)
登録日2016-09-06
公開日2017-09-13
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of CDI complex from E. coli A0 34/86
To Be Published
1HIP
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BU of 1hip by Molmil
TWO-ANGSTROM CRYSTAL STRUCTURE OF OXIDIZED CHROMATIUM HIGH POTENTIAL IRON PROTEIN
分子名称: HIGH POTENTIAL IRON PROTEIN, IRON/SULFUR CLUSTER
著者Carterjunior, C.W, Kraut, J, Freer, S.T, Xuong, N.-H, Alden, R.A, Bartsch, R.G.
登録日1975-04-01
公開日1976-11-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Two-Angstrom crystal structure of oxidized Chromatium high potential iron protein.
J.Biol.Chem., 249, 1974
1QXK
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BU of 1qxk by Molmil
Monoacid-Based, Cell Permeable, Selective Inhibitors of Protein Tyrosine Phosphatase 1B
分子名称: 2-{4-[2-ACETYLAMINO-3-(4-CARBOXYMETHOXY-3-HYDROXY-PHENYL)-PROPIONYLAMINO]-BUTOXY}-6-HYDROXY-BENZOIC ACID METHYL ESTER, Protein-tyrosine phosphatase, non-receptor type 1
著者Xin, Z, Liu, G, Abad-Zapatero, C, Pei, Z, Szczepankiewick, B.G, Li, X, Zhang, T, Hutchins, C.W, Hajduk, P.J, Ballaron, S.J, Stashko, M.A, Lubben, T.H, Trevillyan, J.M, Jirousek, M.R.
登録日2003-09-08
公開日2003-10-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Identification of a Monoacid-Based, Cell Permeable, Selective Inhibitor of Protein Tyrosine Phosphatase 1B
BIOORG.MED.CHEM.LETT., 13, 2003
7XH9
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Crystal structure of a dimeric interlocked parallel G-quadruplex
分子名称: DNA (5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*CP*GP*GP*TP*GP*GP*GP*T)-3'), POTASSIUM ION, STRONTIUM ION
著者Ngo, K.H, Liew, C.W, Lattmann, S, Winnerdy, F.R, Phan, A.T.
登録日2022-04-07
公開日2023-02-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Crystal structures of an HIV-1 integrase aptamer: Formation of a water-mediated A.G.G.G.G pentad in an interlocked G-quadruplex.
Biochem.Biophys.Res.Commun., 613, 2022
7XHD
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BU of 7xhd by Molmil
Crystal structure of a dimeric interlocked parallel G-quadruplex
分子名称: DNA (5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*TP*GP*GP*GP*T)-3'), POTASSIUM ION
著者Ngo, K.H, Liew, C.W, Lattmann, S, Winnerdy, F.R, Phan, A.T.
登録日2022-04-08
公開日2023-02-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Crystal structures of an HIV-1 integrase aptamer: Formation of a water-mediated A•G•G•G•G pentad in an interlocked G-quadruplex.
Biochem.Biophys.Res.Commun., 613, 2022
7XIE
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BU of 7xie by Molmil
Crystal structure of a dimeric interlocked parallel G-quadruplex
分子名称: DNA (5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*GP*GP*GP*TP*GP*GP*GP*T)-3'), POTASSIUM ION
著者Ngo, K.H, Liew, C.W, Lattmann, S, Winnerdy, F.R, Phan, A.T.
登録日2022-04-13
公開日2023-02-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Crystal structures of an HIV-1 integrase aptamer: Formation of a water-mediated A•G•G•G•G pentad in an interlocked G-quadruplex.
Biochem.Biophys.Res.Commun., 613, 2022
6TUT
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BU of 6tut by Molmil
Cryo-EM structure of the RNA Polymerase III-Maf1 complex
分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
著者Vorlaender, M.K, Hagen, W.J.H, Mueller, C.W.
登録日2020-01-08
公開日2020-02-19
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structural basis for RNA polymerase III transcription repression by Maf1.
Nat.Struct.Mol.Biol., 27, 2020
2PX6
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BU of 2px6 by Molmil
Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat
分子名称: (2S,3S,5S)-5-[(N-FORMYL-L-LEUCYL)OXY]-2-HEXYL-3-HYDROXYHEXADECANOIC ACID, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Thioesterase domain
著者Pemble IV, C.W, Johnson, L.C, Kridel, S.J, Lowther, W.T.
登録日2007-05-14
公開日2007-07-10
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat.
Nat.Struct.Mol.Biol., 14, 2007
5WYQ
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BU of 5wyq by Molmil
Crystal Structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa
分子名称: S-ADENOSYLMETHIONINE, tRNA (guanine-N(1)-)-methyltransferase
著者Jaroensuk, J, Liew, C.W, Atichartpongkul, S, Chionh, Y.H, Wong, Y.H, Zhong, W, McBee, M.E, Maenpuen, S, Prestwich, E.G, DeMott, M.S, Mongkolsuk, S, Dedon, P.C, Lescar, J, Fuangthong, M, Chaiyen, P.
登録日2017-01-15
公開日2017-12-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD fromPseudomonas aeruginosa.
Rna, 2019
2PYO
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BU of 2pyo by Molmil
Drosophila nucleosome core
分子名称: CHLORIDE ION, DNA (147-MER), Histone H2A, ...
著者Clapier, C.R, Petosa, C, Mueller, C.W.
登録日2007-05-16
公開日2007-11-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Structure of the Drosophila nucleosome core particle highlights evolutionary constraints on the H2A-H2B histone dimer.
Proteins, 71, 2007
2PVR
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BU of 2pvr by Molmil
Crystal structure of the catalytic subunit of protein kinase CK2 (C-terminal deletion mutant 1-335) in complex with two sulfate ions
分子名称: Casein kinase II subunit alpha, catalytic subunit, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Niefind, K, Yde, C.W, Ermakova, I, Issinger, O.-G.
登録日2007-05-10
公開日2007-06-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.605 Å)
主引用文献Evolved to Be Active: Sulfate Ions Define Substrate Recognition Sites of CK2alpha and Emphasise its Exceptional Role within the CMGC Family of Eukaryotic Protein Kinases
J.Mol.Biol., 370, 2007
5WYR
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BU of 5wyr by Molmil
Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa
分子名称: SINEFUNGIN, tRNA (guanine-N(1)-)-methyltransferase
著者Jaroensuk, J, Liew, C.W, Atichartpongkul, S, Chionh, Y.H, Wong, Y.H, Zhong, W.H, McBee, M.E, Thongdee, N, Prestwich, E.G, DeMott, M.S, Mongkolsuk, S, Dedon, P.C, Lescar, J, Fuangthong, M.
登録日2017-01-15
公開日2017-12-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD fromPseudomonas aeruginosa.
Rna, 2019
3ZYU
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BU of 3zyu by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with I-BET151(GSK1210151A)
分子名称: 1,2-ETHANEDIOL, 7-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-8-METHOXY-1-[(1R)-1-(PYRIDIN-2-YL)ETHYL]-1H,2H,3H-IMIDAZO[4,5-C]QUINOLIN-2-ONE, BROMODOMAIN-CONTAINING PROTEIN 4
著者Chung, C.W, Mirguet, O.
登録日2011-08-25
公開日2011-11-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Inhibition of Bet Recruitment to Chromatin as an Effective Treatment for Mll-Fusion Leukaemia.
Nature, 478, 2011
4N8I
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BU of 4n8i by Molmil
M31G mutant, RipA structure
分子名称: 4-hydroxybutyrate coenzyme A transferase, ACETATE ION, COENZYME A
著者Torres, R, Goulding, C.W.
登録日2013-10-17
公開日2014-04-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.011 Å)
主引用文献Structural snapshots along the reaction pathway of Yersinia pestis RipA, a putative butyryl-CoA transferase.
Acta Crystallogr.,Sect.D, 70, 2014
5WT7
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BU of 5wt7 by Molmil
FAS1-IV domain of Human Periostin
分子名称: Periostin
著者Yun, H, Lee, C.W.
登録日2016-12-09
公開日2017-12-13
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献1H,13C, and 15N resonance assignments of FAS1-IV domain of human periostin, a component of extracellular matrix proteins.
Biomol NMR Assign, 12, 2018
4A9J
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BU of 4a9j by Molmil
N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH N-(4-hydroxyphenyl) acetamide
分子名称: 1,2-ETHANEDIOL, BROMODOMAIN CONTAINING 2, N-(4-HYDROXYPHENYL)ACETAMIDE (TYLENOL), ...
著者Chung, C.W, Bamborough, P.
登録日2011-11-26
公開日2012-01-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Fragment-Based Discovery of Bromodomain Inhibitors Part 1: Inhibitor Binding Modes and Implications for Lead Discovery.
J.Med.Chem., 55, 2012
4N8K
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BU of 4n8k by Molmil
E249A mutant, RipA structure
分子名称: Putative 4-hydroxybutyrate coenzyme A transferase
著者Torres, R, Goulding, C.W.
登録日2013-10-17
公開日2014-04-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural snapshots along the reaction pathway of Yersinia pestis RipA, a putative butyryl-CoA transferase.
Acta Crystallogr.,Sect.D, 70, 2014
3BO0
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BU of 3bo0 by Molmil
Ribosome-SecY complex
分子名称: 23S RIBOSOMAL RNA, PREPROTEIN TRANSLOCASE SecE SUBUNIT, PREPROTEIN TRANSLOCASE SecY SUBUNIT, ...
著者Akey, C.W, Menetret, J.F.
登録日2007-12-15
公開日2008-12-09
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (9.6 Å)
主引用文献Ribosome binding of a single copy of the SecY complex: implications for protein translocation
Mol.Cell, 28, 2007
3BXL
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BU of 3bxl by Molmil
Crystal structure of the R-type calcium channeL (CaV2.3) IQ domain and CA2+calmodulin complex
分子名称: CALCIUM ION, Calmodulin, SULFATE ION, ...
著者Mori, M.X, Vander Kooi, C.W, Leahy, D.J, Yue, D.T.
登録日2008-01-14
公開日2008-03-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the CaV2 IQ domain in complex with Ca2+/calmodulin
To be Published
3PHP
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BU of 3php by Molmil
STRUCTURE OF THE 3' HAIRPIN OF THE TYMV PSEUDOKNOT: PREFORMATION IN RNA FOLDING
分子名称: RNA (5'-R(*GP*GP*UP*UP*CP*CP*GP*AP*GP*GP*GP*UP*CP*AP*UP*CP*GP*GP*AP*AP*CP*CP*A) -3')
著者Kolk, M.H, Van Der Graaf, M, Wijmenga, S.S, Pleij, C.W.A, Heus, H.A, Hilbers, C.W.
登録日1998-10-13
公開日1998-10-21
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of the 3'-hairpin of the TYMV pseudoknot: preformation in RNA folding.
EMBO J., 17, 1998
1GTQ
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BU of 1gtq by Molmil
6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE
分子名称: 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE, ZINC ION
著者Nar, H, Huber, R, Heizmann, C.W, Thoeny, B, Buergisser, D.
登録日1995-09-16
公開日1996-04-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Three-dimensional structure of 6-pyruvoyl tetrahydropterin synthase, an enzyme involved in tetrahydrobiopterin biosynthesis.
EMBO J., 13, 1994
3KCW
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BU of 3kcw by Molmil
Crystal structure of Ganoderma fungal immunomodulatory protein, GMI
分子名称: immunomodulatory protein
著者Hsu, M.F, Wang, A.H.J, Yang, C.S, Huang, C.T, Hseu, R.S, Lin, C.W, Wu, M.Y, Huang, C.S, Fu, H.Y.
登録日2009-10-22
公開日2010-11-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Single cysteine replacement at Leu6 increase the potent and thermostability in Ganoderma fungal immunomodulatory proteins
To be Published
3KVF
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BU of 3kvf by Molmil
Crystal structure of the I93M mutant of ubiquitin carboxy terminal hydrolase L1 bound to ubiquitin vinylmethylester
分子名称: METHYL 4-AMINOBUTANOATE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase isozyme L1
著者Davies, C.W, Maiti, T.K, Das, C.
登録日2009-11-30
公開日2010-06-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation.
Proc.Natl.Acad.Sci.USA, 107, 2010
7LJP
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BU of 7ljp by Molmil
Structure of Thermotoga maritima SmpB
分子名称: 1,4-DIETHYLENE DIOXIDE, GLYCEROL, SULFATE ION, ...
著者Chan, C.W, Mondragon, A.
登録日2021-01-29
公開日2022-02-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of Thermotoga maritima SmpB reveals its C-terminal tail domain in a helical conformation mimicking that of a ribosome-bound state
To Be Published

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