1AFX
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1B36
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1TLR
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4N0T
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![BU of 4n0t by Molmil](/molmil-images/mine/4n0t) | Core structure of the U6 small nuclear ribonucleoprotein at 1.7 Angstrom resolution | Descriptor: | SULFATE ION, U4/U6 snRNA-associated-splicing factor PRP24, U6 snRNA | Authors: | Montemayor, E.J, Curran, E.C, Liao, H, Andrews, K.L, Treba, C.N, Butcher, S.E, Brow, D.A. | Deposit date: | 2013-10-02 | Release date: | 2014-05-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Core structure of the U6 small nuclear ribonucleoprotein at 1.7- angstrom resolution. Nat.Struct.Mol.Biol., 21, 2014
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7MKT
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![BU of 7mkt by Molmil](/molmil-images/mine/7mkt) | Crystal structure of r(GU)11G-NMM complex | Descriptor: | N-METHYLMESOPORPHYRIN, POTASSIUM ION, RNA (5'-R(*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*G)-3') | Authors: | Bingman, C.A, Roschdi, S, Nomura, Y, Butcher, S.E. | Deposit date: | 2021-04-26 | Release date: | 2022-11-02 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | An atypical RNA quadruplex marks RNAs as vectors for gene silencing. Nat.Struct.Mol.Biol., 29, 2022
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8TNS
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6E7L
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![BU of 6e7l by Molmil](/molmil-images/mine/6e7l) | Structure of a dimerized UUCG motif | Descriptor: | RNA (5'-R(*GP*GP*GP*CP*UP*GP*CP*AP*CP*UP*UP*CP*GP*GP*UP*GP*CP*UP*GP*CP*CP*C)-3') | Authors: | Montemayor, E.J, Butcher, S.E. | Deposit date: | 2018-07-26 | Release date: | 2019-07-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Structure of an RNA helix with pyrimidine mismatches and cross-strand stacking. Acta Crystallogr.,Sect.F, 75, 2019
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5UQJ
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![BU of 5uqj by Molmil](/molmil-images/mine/5uqj) | Structure of yeast Usb1 | Descriptor: | ACETATE ION, GLYCEROL, SULFATE ION, ... | Authors: | Didychuk, A.L, Montemayor, E.J, Butcher, S.E. | Deposit date: | 2017-02-08 | Release date: | 2017-08-16 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Usb1 controls U6 snRNP assembly through evolutionarily divergent cyclic phosphodiesterase activities. Nat Commun, 8, 2017
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5V1M
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![BU of 5v1m by Molmil](/molmil-images/mine/5v1m) | Structure of human Usb1 with uridine 5'-monophosphate | Descriptor: | CHLORIDE ION, GLYCEROL, U6 snRNA phosphodiesterase, ... | Authors: | Montemayor, E.J, Didychuk, A.L, Butcher, S.E. | Deposit date: | 2017-03-02 | Release date: | 2017-08-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Usb1 controls U6 snRNP assembly through evolutionarily divergent cyclic phosphodiesterase activities. Nat Commun, 8, 2017
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5TF6
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![BU of 5tf6 by Molmil](/molmil-images/mine/5tf6) | Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core | Descriptor: | CHLORIDE ION, GLYCEROL, POTASSIUM ION, ... | Authors: | Montemayor, E.J, Brow, D.A, Butcher, S.E. | Deposit date: | 2016-09-24 | Release date: | 2017-01-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core. Acta Crystallogr D Struct Biol, 73, 2017
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1PJY
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1NC0
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1NZ1
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![BU of 1nz1 by Molmil](/molmil-images/mine/1nz1) | Solution structure of the S. cerevisiae U6 Intramolecular stem-loop containing an SP phosphorothioate at nucleotide U80 | Descriptor: | SP U6 Intramolecular Stem-Loop RNA | Authors: | Reiter, N.J, Nikstad, L.J, Allman, A.M, Johnson, R.J, Butcher, S.E. | Deposit date: | 2003-02-14 | Release date: | 2003-05-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the U6 RNA intramolecular stem-loop harboring an
S(P)-phosphorothioate modification. RNA, 9, 2003
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6PPN
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![BU of 6ppn by Molmil](/molmil-images/mine/6ppn) | Structure of S. pombe Lsm2-8 with unprocessed U6 snRNA | Descriptor: | Mimic of unprocessed U6 snRNA, Probable U6 snRNA-associated Sm-like protein LSm3, Probable U6 snRNA-associated Sm-like protein LSm4, ... | Authors: | Montemayor, E.J, Butcher, S.E. | Deposit date: | 2019-07-08 | Release date: | 2020-06-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes. Rna, 26, 2020
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6PFQ
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6PPQ
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6PGL
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![BU of 6pgl by Molmil](/molmil-images/mine/6pgl) | Structure of Kluyveromyces marxianus Usb1 with uridine monophosphate | Descriptor: | 1,2-ETHANEDIOL, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, GLYCEROL, ... | Authors: | Nomura, Y, Montemayor, E.J, Butcher, S.E. | Deposit date: | 2019-06-24 | Release date: | 2019-12-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.845 Å) | Cite: | Structural basis for the evolution of cyclic phosphodiesterase activity in the U6 snRNA exoribonuclease Usb1. Nucleic Acids Res., 48, 2020
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6PPV
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6PPP
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![BU of 6ppp by Molmil](/molmil-images/mine/6ppp) | Structure of S. pombe Lsm2-8 with processed U6 snRNA | Descriptor: | Mimic of processed U6 snRNA, Probable U6 snRNA-associated Sm-like protein LSm3, Probable U6 snRNA-associated Sm-like protein LSm4, ... | Authors: | Montemayor, E.J, Butcher, S.E. | Deposit date: | 2019-07-08 | Release date: | 2020-06-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes. Rna, 26, 2020
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6D31
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![BU of 6d31 by Molmil](/molmil-images/mine/6d31) | Structure of human Usb1 with adenosine 5'-monophosphate | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | Authors: | Nomura, Y, Montemayor, E.J, Butcher, S.E. | Deposit date: | 2018-04-14 | Release date: | 2018-09-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural and mechanistic basis for preferential deadenylation of U6 snRNA by Usb1. Nucleic Acids Res., 46, 2018
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6D2Z
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![BU of 6d2z by Molmil](/molmil-images/mine/6d2z) | Structure of human Usb1 with uridine-adenosine, inactive H208Q mutant | Descriptor: | 5'-R(UP*A)-3'), CHLORIDE ION, U6 snRNA phosphodiesterase | Authors: | Nomura, Y, Montemayor, E.J, Butcher, S.E. | Deposit date: | 2018-04-14 | Release date: | 2018-09-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.18 Å) | Cite: | Structural and mechanistic basis for preferential deadenylation of U6 snRNA by Usb1. Nucleic Acids Res., 46, 2018
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6D30
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![BU of 6d30 by Molmil](/molmil-images/mine/6d30) | Structure of human Usb1 with uridine-uridine, inactive H208Q mutant | Descriptor: | CHLORIDE ION, RNA (5'-R(UP*U)-3'), U6 snRNA phosphodiesterase | Authors: | Nomura, Y, Montemayor, E.J, Butcher, S.E. | Deposit date: | 2018-04-14 | Release date: | 2018-09-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.17 Å) | Cite: | Structural and mechanistic basis for preferential deadenylation of U6 snRNA by Usb1. Nucleic Acids Res., 46, 2018
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6ASO
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![BU of 6aso by Molmil](/molmil-images/mine/6aso) | Structure of yeast U6 snRNP with 3'-phosphate terminated U6 RNA | Descriptor: | MAGNESIUM ION, MANGANESE (II) ION, POTASSIUM ION, ... | Authors: | Montemayor, E.J, Brow, D.A, Butcher, S.E. | Deposit date: | 2017-08-25 | Release date: | 2018-05-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA. Nat Commun, 9, 2018
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1K4B
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![BU of 1k4b by Molmil](/molmil-images/mine/1k4b) | STRUCTURE OF AGUU RNA TETRALOOP, NMR, 20 STRUCTURES | Descriptor: | 5'-R(*GP*GP*UP*UP*CP*AP*GP*UP*UP*GP*AP*AP*CP*C)-3' | Authors: | Wu, H, Yang, P.K, Butcher, S.E, Kang, S, Chanfreau, G, Feigon, J. | Deposit date: | 2001-10-07 | Release date: | 2001-12-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A novel family of RNA tetraloop structure forms the recognition site for Saccharomyces cerevisiae RNase III. EMBO J., 20, 2001
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1K4A
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![BU of 1k4a by Molmil](/molmil-images/mine/1k4a) | STRUCTURE OF AGAA RNA TETRALOOP, NMR, 20 STRUCTURES | Descriptor: | 5'-R(*GP*GP*UP*UP*CP*AP*GP*AP*AP*GP*AP*AP*CP*C)-3' | Authors: | Wu, H, Yang, P.K, Butcher, S.E, Kang, S, Chanfreau, G, Feigon, J. | Deposit date: | 2001-10-07 | Release date: | 2001-12-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A novel family of RNA tetraloop structure forms the recognition site for Saccharomyces cerevisiae RNase III. EMBO J., 20, 2001
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