6D30

Structure of human Usb1 with uridine-uridine, inactive H208Q mutant

Summary for 6D30

• Entry DOI: 10.2210/pdb6d30/pdb
• Descriptor: U6 snRNA phosphodiesterase, RNA (5'-R(UP*U)-3'), CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: exonuclease, u6 snrna, 2h phosphodiesterase superfamily, hydrolase, hydrolase-rna complex, hydrolase/rna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 22779.31

Authors

Nomura, Y.,Montemayor, E.J.,Butcher, S.E. (deposition date: 2018-04-14, release date: 2018-09-05, Last modification date: 2023-10-04)

• Primary citation: Nomura, Y.,Roston, D.,Montemayor, E.J.,Cui, Q.,Butcher, S.E.; Structural and mechanistic basis for preferential deadenylation of U6 snRNA by Usb1.; Nucleic Acids Res., 46:11488-11501, 2018; PubMed: 30215753; DOI: 10.1093/nar/gky812

Experimental method

X-RAY DIFFRACTION (1.17 Å)