1AFX
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1B36
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1TLR
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![BU of 1tlr by Molmil](/molmil-images/mine/1tlr) | |
6PPP
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![BU of 6ppp by Molmil](/molmil-images/mine/6ppp) | Structure of S. pombe Lsm2-8 with processed U6 snRNA | Descriptor: | Mimic of processed U6 snRNA, Probable U6 snRNA-associated Sm-like protein LSm3, Probable U6 snRNA-associated Sm-like protein LSm4, ... | Authors: | Montemayor, E.J, Butcher, S.E. | Deposit date: | 2019-07-08 | Release date: | 2020-06-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes. Rna, 26, 2020
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1SY4
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![BU of 1sy4 by Molmil](/molmil-images/mine/1sy4) | Refined solution structure of the S. cerevisiae U6 INTRAMOLECULAR STEM LOOP (ISL) RNA USING RESIDUAL DIPOLAR COUPLINGS (RDCS) | Descriptor: | U6 Intramolecular Stem-Loop RNA | Authors: | Reiter, N.J, Nikstad, L.J, Allman, A.M, Johnson, R.J, Butcher, S.E. | Deposit date: | 2004-03-31 | Release date: | 2004-04-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the U6 RNA intramolecular stem-loop harboring an
S(P)-phosphorothioate modification. RNA, 9, 2003
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7Z51
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![BU of 7z51 by Molmil](/molmil-images/mine/7z51) | Tick-borne encephalitis virus Kuutsalo-14 | Descriptor: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | Authors: | Pulkkinen, L.I.A, Barrass, S.V, Anastasina, M, Butcher, S.J. | Deposit date: | 2022-03-07 | Release date: | 2022-04-20 | Last modified: | 2022-05-04 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular Organisation of Tick-Borne Encephalitis Virus. Viruses, 14, 2022
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8PPQ
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7MKT
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![BU of 7mkt by Molmil](/molmil-images/mine/7mkt) | Crystal structure of r(GU)11G-NMM complex | Descriptor: | N-METHYLMESOPORPHYRIN, POTASSIUM ION, RNA (5'-R(*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*G)-3') | Authors: | Bingman, C.A, Roschdi, S, Nomura, Y, Butcher, S.E. | Deposit date: | 2021-04-26 | Release date: | 2022-11-02 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | An atypical RNA quadruplex marks RNAs as vectors for gene silencing. Nat.Struct.Mol.Biol., 29, 2022
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5MJV
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![BU of 5mjv by Molmil](/molmil-images/mine/5mjv) | Rebuild and re-refined model for Human Parechovirus 1 | Descriptor: | CAPSID SUBUNIT VP0, CAPSID SUBUNIT VP1, CAPSID SUBUNIT VP3, ... | Authors: | Shakeel, S, Dykeman, E.C, White, S.J, Ora, A, Cockburn, J.J.B, Butcher, S.J, Stockley, P.G, Twarock, R. | Deposit date: | 2016-12-01 | Release date: | 2017-01-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Genomic RNA folding mediates assembly of human parechovirus. Nat Commun, 8, 2017
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5E4V
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![BU of 5e4v by Molmil](/molmil-images/mine/5e4v) | Crystal structure of measles N0-P complex | Descriptor: | Nucleoprotein,Phosphoprotein | Authors: | Guryanov, S.G, Liljeroos, L, Kasaragod, P, Kajander, T, Butcher, S.J. | Deposit date: | 2015-10-07 | Release date: | 2016-01-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Crystal Structure of the Measles Virus Nucleoprotein Core in Complex with an N-Terminal Region of Phosphoprotein. J.Virol., 90, 2015
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8TNS
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6ASO
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![BU of 6aso by Molmil](/molmil-images/mine/6aso) | Structure of yeast U6 snRNP with 3'-phosphate terminated U6 RNA | Descriptor: | MAGNESIUM ION, MANGANESE (II) ION, POTASSIUM ION, ... | Authors: | Montemayor, E.J, Brow, D.A, Butcher, S.E. | Deposit date: | 2017-08-25 | Release date: | 2018-05-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA. Nat Commun, 9, 2018
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6RJF
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![BU of 6rjf by Molmil](/molmil-images/mine/6rjf) | Echovirus 1 intact particle | Descriptor: | PALMITIC ACID, VP1, VP2, ... | Authors: | Domanska, A, Ruokolainen, V.P, Pelliccia, M, Laajala, M.A, Marjomaki, V.S, Butcher, S.J. | Deposit date: | 2019-04-26 | Release date: | 2019-06-12 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Extracellular Albumin and Endosomal Ions Prime Enterovirus Particles for Uncoating That Can Be Prevented by Fatty Acid Saturation. J.Virol., 93, 2019
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5APM
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![BU of 5apm by Molmil](/molmil-images/mine/5apm) | Multiple capsid-stabilizing protein-RNA and protein-protein interactions revealed in a high-resolution structure of an emerging picornavirus causing neonatal sepsis | Descriptor: | VP0, VP1, VP3 | Authors: | Shakeel, S, Westerhuis, B.M, Domanska, A, Koning, R.I, Matadeen, R, Koster, A.J, Bakker, A.Q, Beaumont, T, Wolthers, K.C, Butcher, S.J. | Deposit date: | 2015-09-17 | Release date: | 2016-07-27 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Multiple Capsid-Stabilizing Interactions Revealed in a High-Resolution Structure of an Emerging Picornavirus Causing Neonatal Sepsis Nat.Commun., 7, 2016
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5TF6
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![BU of 5tf6 by Molmil](/molmil-images/mine/5tf6) | Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core | Descriptor: | CHLORIDE ION, GLYCEROL, POTASSIUM ION, ... | Authors: | Montemayor, E.J, Brow, D.A, Butcher, S.E. | Deposit date: | 2016-09-24 | Release date: | 2017-01-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core. Acta Crystallogr D Struct Biol, 73, 2017
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3J2J
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![BU of 3j2j by Molmil](/molmil-images/mine/3j2j) | Empty coxsackievirus A9 capsid | Descriptor: | Protein VP1, Protein VP2, Protein VP3 | Authors: | Shakeel, S, Seitsonen, J.J.T, Kajander, T, Laurinmaki, P, Hyypia, T, Susi, P, Butcher, S.J. | Deposit date: | 2012-10-04 | Release date: | 2013-07-17 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9.54 Å) | Cite: | Structural and functional analysis of coxsackievirus A9 integrin {alpha}v{beta}6 binding and uncoating. J.Virol., 87, 2013
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4BIQ
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![BU of 4biq by Molmil](/molmil-images/mine/4biq) | Homology model of coxsackievirus A7 (CAV7) empty capsid proteins. | Descriptor: | VP1, VP2, VP3 | Authors: | Seitsonen, J.J.T, Shakeel, S, Susi, P, Pandurangan, A.P, Sinkovits, R.S, Hyvonen, H, Laurinmaki, P, Yla-Pelto, J, Topf, M, Hyypia, T, Butcher, S.J. | Deposit date: | 2013-04-12 | Release date: | 2013-10-02 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.09 Å) | Cite: | Combined Approaches to Flexible Fitting and Assessment in Virus Capsids Undergoing Conformational Change. J.Struct.Biol., 185, 2014
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4UDF
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![BU of 4udf by Molmil](/molmil-images/mine/4udf) | STRUCTURAL BASIS OF HUMAN PARECHOVIRUS NEUTRALIZATION BY HUMAN MONOCLONAL ANTIBODIES | Descriptor: | HUMAN MONOCLONAL ANTIBODY, Protein VP0, Protein VP3 | Authors: | Shakeel, S, Westerhuis, B.M, Ora, A, Koen, G, Bakker, A.Q, Claassen, Y, Beaumont, T, Wolthers, K.C, Butcher, S.J. | Deposit date: | 2014-12-10 | Release date: | 2015-07-22 | Last modified: | 2018-10-03 | Method: | ELECTRON MICROSCOPY (20 Å) | Cite: | Structural Basis of Human Parechovirus Neutralization by Human Monoclonal Antibodies. J. Virol., 89, 2015
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4BIP
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![BU of 4bip by Molmil](/molmil-images/mine/4bip) | Homology model of coxsackievirus A7 (CAV7) full capsid proteins. | Descriptor: | VP1, VP2, VP3 | Authors: | Seitsonen, J.J.T, Shakeel, S, Susi, P, Pandurangan, A.P, Sinkovits, R.S, Hyvonen, H, Laurinmaki, P, Yla-Pelto, J, Topf, M, Hyypia, T, Butcher, S.J. | Deposit date: | 2013-04-12 | Release date: | 2013-10-02 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.23 Å) | Cite: | Combined Approaches to Flexible Fitting and Assessment in Virus Capsids Undergoing Conformational Change. J.Struct.Biol., 185, 2014
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4N0T
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![BU of 4n0t by Molmil](/molmil-images/mine/4n0t) | Core structure of the U6 small nuclear ribonucleoprotein at 1.7 Angstrom resolution | Descriptor: | SULFATE ION, U4/U6 snRNA-associated-splicing factor PRP24, U6 snRNA | Authors: | Montemayor, E.J, Curran, E.C, Liao, H, Andrews, K.L, Treba, C.N, Butcher, S.E, Brow, D.A. | Deposit date: | 2013-10-02 | Release date: | 2014-05-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Core structure of the U6 small nuclear ribonucleoprotein at 1.7- angstrom resolution. Nat.Struct.Mol.Biol., 21, 2014
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8AXX
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![BU of 8axx by Molmil](/molmil-images/mine/8axx) | Expanded Coxsackievirus A9 after treatment with endosomal ionic buffer | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | Authors: | Domanska, A, Plavec, Z, Ruokolainen, V, Loflund, B, Marjomaki, V.S, Butcher, S.J. | Deposit date: | 2022-09-01 | Release date: | 2022-10-19 | Last modified: | 2023-02-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural Studies Reveal that Endosomal Cations Promote Formation of Infectious Coxsackievirus A9 A-Particles, Facilitating RNA and VP4 Release. J.Virol., 96, 2022
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6ZCK
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![BU of 6zck by Molmil](/molmil-images/mine/6zck) | Coxsackievirus B4 in complex with capsid binder compound 48 | Descriptor: | 4-[(6-propoxynaphthalen-2-yl)sulfonylamino]benzoic acid, Capsid protein VP1, Capsid protein VP2, ... | Authors: | Flatt, J.W, Domanska, A, Butcher, S.J. | Deposit date: | 2020-06-11 | Release date: | 2021-03-17 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Identification of a conserved virion-stabilizing network inside the interprotomer pocket of enteroviruses. Commun Biol, 4, 2021
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8AW6
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![BU of 8aw6 by Molmil](/molmil-images/mine/8aw6) | Expanded Coxsackievirus A9 after 0.01% faf-BSA treatment | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | Authors: | Domanska, A, Plavec, Z, Ruokolainen, V, Loflund, B, Marjomaki, V.S, Butcher, S.J. | Deposit date: | 2022-08-29 | Release date: | 2022-10-26 | Last modified: | 2023-02-01 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural Studies Reveal that Endosomal Cations Promote Formation of Infectious Coxsackievirus A9 A-Particles, Facilitating RNA and VP4 Release. J.Virol., 96, 2022
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8AT5
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![BU of 8at5 by Molmil](/molmil-images/mine/8at5) | native Coxsackievirus A9 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Domanska, A, Plavec, Z, Ruokolainen, V, Marjomaki, V.S, Butcher, S.J. | Deposit date: | 2022-08-22 | Release date: | 2022-11-16 | Last modified: | 2023-02-01 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural Studies Reveal that Endosomal Cations Promote Formation of Infectious Coxsackievirus A9 A-Particles, Facilitating RNA and VP4 Release. J.Virol., 96, 2022
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6GZV
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![BU of 6gzv by Molmil](/molmil-images/mine/6gzv) | Identification of a druggable VP1-VP3 interprotomer pocket in the capsid of enteroviruses | Descriptor: | 4-[[4-[1,3-bis(oxidanylidene)isoindol-2-yl]phenyl]sulfonylamino]benzoic acid, Capsid protein VP1, Capsid protein VP2, ... | Authors: | Geraets, J.A, Flatt, J.W, Domanska, A, Butcher, S.J. | Deposit date: | 2018-07-05 | Release date: | 2019-06-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | A novel druggable interprotomer pocket in the capsid of rhino- and enteroviruses. Plos Biol., 17, 2019
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