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PDB: 11 件

3U1Y
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Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections
分子名称: (2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-{4'-[3-(morpholin-4-yl)propoxy]biphenyl-4-yl}butanamide, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ZINC ION
著者Brown, M, Abramite, J, Liu, S.
登録日2011-09-30
公開日2012-01-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Potent inhibitors of LpxC for the treatment of Gram-negative infections.
J.Med.Chem., 55, 2012
6YBA
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HAdV-F41 Capsid
分子名称: Hexon protein, Hexon-interlacing protein, Penton protein, ...
著者Perez Illana, M, Martinez, M, Mangroo, C, Brown, M, Marabini, R, San Martin, C.
登録日2020-03-16
公開日2021-03-10
最終更新日2021-03-17
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structure of enteric adenovirus HAdV-F41 highlights structural variations among human adenoviruses.
Sci Adv, 7, 2021
1DL7
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THE STRUCTURAL BASIS OF REPERTOIRE SHIFT IN AN IMMUNE RESPONSE TO PHOSPHOCHOLINE
分子名称: P-NITROPHENYL-PHOSPHOCHOLINE, PROTEIN (ANTIBODY M3C65 (HEAVY CHAIN)), PROTEIN (ANTIBODY M3C65 (LIGHT CHAIN))
著者Schumacher, M, Brown, M.
登録日1999-12-08
公開日2000-12-13
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The structural basis of repertoire shift in an immune response to phosphocholine.
J.Exp.Med., 191, 2000
1VZO
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The structure of the N-terminal kinase domain of MSK1 reveals a novel autoinhibitory conformation for a dual kinase protein
分子名称: BETA-MERCAPTOETHANOL, RIBOSOMAL PROTEIN S6 KINASE ALPHA 5, SULFATE ION
著者Smith, K.J, Carter, P.S, Bridges, A, Horrocks, P, Lewis, C, Pettman, G, Clarke, A, Brown, M, Hughes, J, Wilkinson, M, Bax, B, Reith, A.
登録日2004-05-21
公開日2004-06-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Structure of Msk1 Reveals a Novel Autoinhibitory Conformation for a Dual Kinase Protein
Structure, 12, 2004
6RB9
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The pore structure of Clostridium perfringens epsilon toxin
分子名称: Epsilon-toxin type B
著者Savva, C.G, Clark, A.R, Naylor, C.E, Popoff, M.R, Moss, D.S, Basak, A.K, Titball, R.W, Bokori-Brown, M.
登録日2019-04-09
公開日2019-06-19
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The pore structure of Clostridium perfringens epsilon toxin.
Nat Commun, 10, 2019
3JCA
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Core model of the Mouse Mammary Tumor Virus intasome
分子名称: 5'-D(*AP*AP*TP*GP*CP*CP*GP*CP*AP*GP*TP*CP*GP*GP*CP*CP*GP*AP*CP*CP*TP*G)-3', 5'-D(*CP*AP*GP*GP*TP*CP*GP*GP*CP*CP*GP*AP*CP*TP*GP*CP*GP*GP*CP*A)-3', Integrase, ...
著者Lyumkis, D.L, Ballandras-Colas, A, Brown, M, Cook, N.J, Dewdney, T.G, Demeler, B, Cherepanov, P, Engelman, A.N.
登録日2015-11-24
公開日2016-02-17
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function.
Nature, 530, 2016
5GAQ
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Cryo-EM structure of the Lysenin Pore
分子名称: Lysenin
著者Savva, C.G, Bokori-Brown, M, Martin, T.G, Titball, R.W, Naylor, C.E, Basak, A.K.
登録日2016-01-05
公開日2016-04-06
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structure of lysenin pore elucidates membrane insertion by an aerolysin family protein
Nat Commun, 7, 2016
3ZJX
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Clostridium perfringens epsilon toxin mutant H149A bound to octyl glucoside
分子名称: EPSILON-TOXIN, PHOSPHATE ION, octyl beta-D-glucopyranoside
著者Bokori-Brown, M, Kokkinidou, M.C, Savva, C.G, Fernandes da Costa, S.P, Naylor, C.E, Cole, A.R, Basak, A.K, Titball, R.W.
登録日2013-01-20
公開日2013-03-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Clostridium Perfringens Epsilon Toxin H149A Mutant as a Platform for Receptor Binding Studies.
Protein Sci., 22, 2013
4H56
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Crystal structure of the Clostridium perfringens NetB toxin in the membrane inserted form
分子名称: Necrotic enteritis toxin B
著者Savva, C.G, Fernandes da Costa, S.P, Bokori-Brown, M, Naylor, C, Cole, A.R, Moss, D.S, Titball, R.W, Basak, A.K.
登録日2012-09-18
公開日2012-12-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Molecular Architecture and Functional Analysis of NetB, a Pore-forming Toxin from Clostridium perfringens.
J.Biol.Chem., 288, 2013
4J5P
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Crystal Structure of a Covalently Bound alpha-Ketoheterocycle Inhibitor (Phenhexyl/Oxadiazole/Pyridine) to a Humanized Variant of Fatty Acid Amide Hydrolase
分子名称: (1S)-1-{5-[5-(bromomethyl)pyridin-2-yl]-1,3-oxazol-2-yl}-7-phenylheptan-1-ol, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Otrubova, K, Brown, M, McCormick, M.S, Han, G.W, O'Neal, S.T, Cravatt, B.F, Stevens, R.C, Lichtman, A.H, Boger, D.L.
登録日2013-02-08
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Rational design of Fatty Acid amide hydrolase inhibitors that act by covalently bonding to two active site residues.
J.Am.Chem.Soc., 135, 2013
3RU0
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Cocrystal structure of human SMYD3 with inhibitor Sinefungin bound
分子名称: SET and MYND domain-containing protein 3, SINEFUNGIN, ZINC ION
著者Foreman, K.W, Brown, M, Park, F, Emtage, S, Harriss, J, Das, C, Zhu, L, Crew, A, Arnold, L, Shaaban, S, Tucker, P.
登録日2011-05-04
公開日2011-05-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献Structural and Functional Profiling of the Human Histone Methyltransferase SMYD3.
Plos One, 6, 2011

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件を2024-05-15に公開中

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