3JCA
Core model of the Mouse Mammary Tumor Virus intasome
Summary for 3JCA
Entry DOI | 10.2210/pdb3jca/pdb |
EMDB information | 6440 6441 |
Descriptor | Integrase, 5'-D(*AP*AP*TP*GP*CP*CP*GP*CP*AP*GP*TP*CP*GP*GP*CP*CP*GP*AP*CP*CP*TP*G)-3', 5'-D(*CP*AP*GP*GP*TP*CP*GP*GP*CP*CP*GP*AP*CP*TP*GP*CP*GP*GP*CP*A)-3', ... (5 entities in total) |
Functional Keywords | integration, retrovirus, integrase, intasome, viral protein |
Biological source | Mouse mammary tumor virus (MMTV) More |
Total number of polymer chains | 12 |
Total formula weight | 168483.30 |
Authors | Lyumkis, D.L.,Ballandras-Colas, A.,Brown, M.,Cook, N.J.,Dewdney, T.G.,Demeler, B.,Cherepanov, P.,Engelman, A.N. (deposition date: 2015-11-24, release date: 2016-02-17, Last modification date: 2024-02-21) |
Primary citation | Ballandras-Colas, A.,Brown, M.,Cook, N.J.,Dewdney, T.G.,Demeler, B.,Cherepanov, P.,Lyumkis, D.,Engelman, A.N. Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function. Nature, 530:358-361, 2016 Cited by PubMed: 26887496DOI: 10.1038/nature16955 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.8 Å) |
Structure validation
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