3DAR
 
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7A6O
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2AHB
 | | X-ray crystal structure of R46A,R161A mutant of Mycobacterium tuberculosis FabH | | 分子名称: | Beta- ketoacyl-ACP synthase III | | 著者 | Brown, A.K, Sridharan, S, Kremer, L, Lindenberg, S, Dover, L.G, Sacchettini, J.C, Besra, G.S. | | 登録日 | 2005-07-27 | | 公開日 | 2005-08-23 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Probing the Mechanism of the Mycobacterium tuberculosis {beta}-Ketoacyl-Acyl Carrier Protein Synthase III mtFabH: FACTORS INFLUENCING CATALYSIS AND SUBSTRATE SPECIFICITY
J.Biol.Chem., 280, 2005
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2AJ9
 | | X-ray crystal structure of W42A,R161A double mutant of Mycobacterium tuberculosis beta-ketoacyl-ACP synthase III | | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase III | | 著者 | Brown, A.K, Sridharan, S, Kremer, L, Lindenberg, S, Dover, L.G, Sacchettini, J.C, Besra, G.S. | | 登録日 | 2005-08-01 | | 公開日 | 2005-08-30 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Probing the Mechanism of the Mycobacterium tuberculosis beta-Ketoacyl-Acyl Carrier Protein Synthase III mtFabH: Factors Influencing Catalysis And Substrate Specificity.
J.Biol.Chem., 280, 2005
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6MTD
 | | Rabbit 80S ribosome with eEF2 and SERBP1 (unrotated state with 40S head swivel) | | 分子名称: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | | 著者 | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | | 登録日 | 2018-10-19 | | 公開日 | 2018-11-21 | | 最終更新日 | 2019-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
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6MTE
 | | Rabbit 80S ribosome with eEF2 and SERBP1 (rotated state) | | 分子名称: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | | 著者 | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | | 登録日 | 2018-10-19 | | 公開日 | 2018-11-21 | | 最終更新日 | 2019-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
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6MTC
 | | Rabbit 80S ribosome with Z-site tRNA and IFRD2 (unrotated state) | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | 著者 | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | | 登録日 | 2018-10-19 | | 公開日 | 2018-11-21 | | 最終更新日 | 2019-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
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6MTB
 | | Rabbit 80S ribosome with P- and Z-site tRNAs (unrotated state) | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | 著者 | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | | 登録日 | 2018-10-19 | | 公開日 | 2018-11-21 | | 最終更新日 | 2019-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
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4CJM
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5IQR
 | | Structure of RelA bound to the 70S ribosome | | 分子名称: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | | 著者 | Brown, A, Fernandez, I.S, Gordiyenko, Y, Ramakrishnan, V. | | 登録日 | 2016-03-11 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Ribosome-dependent activation of stringent control.
Nature, 534, 2016
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3JAG
 | | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAA stop codon | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | | 著者 | Brown, A, Shao, S, Murray, J, Hegde, R.S, Ramakrishnan, V. | | 登録日 | 2015-06-10 | | 公開日 | 2015-08-12 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | | 主引用文献 | Structural basis for stop codon recognition in eukaryotes.
Nature, 524, 2015
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3JAH
 | | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAG stop codon | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | | 著者 | Brown, A, Shao, S, Murray, J, Hegde, R.S, Ramakrishnan, V. | | 登録日 | 2015-06-10 | | 公開日 | 2015-08-12 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Structural basis for stop codon recognition in eukaryotes.
Nature, 524, 2015
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3JAI
 | | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UGA stop codon | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | | 著者 | Brown, A, Shao, S, Murray, J, Hegde, R.S, Ramakrishnan, V. | | 登録日 | 2015-06-10 | | 公開日 | 2015-08-12 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | | 主引用文献 | Structural basis for stop codon recognition in eukaryotes.
Nature, 524, 2015
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2Q74
 | | Mycobacterium tuberculosis SuhB | | 分子名称: | Inositol-1-monophosphatase | | 著者 | Brown, A.K, Meng, G, Ghadbane, H, Besra, G.S, Futterer, K. | | 登録日 | 2007-06-06 | | 公開日 | 2007-10-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Dimerization of inositol monophosphatase Mycobacterium tuberculosis SuhB is not constitutive, but induced by binding of the activator Mg2+
Bmc Struct.Biol., 7, 2007
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3J7Y
 | | Structure of the large ribosomal subunit from human mitochondria | | 分子名称: | 16S rRNA, ADENOSINE MONOPHOSPHATE, CRIF1, ... | | 著者 | Brown, A, Amunts, A, Bai, X.C, Sugimoto, Y, Edwards, P.C, Murshudov, G, Scheres, S.H.W, Ramakrishnan, V. | | 登録日 | 2014-08-26 | | 公開日 | 2014-10-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of the large ribosomal subunit from human mitochondria.
Science, 346, 2014
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5OOL
 | | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rRNA | | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Brown, A, Rathore, S, Kimanius, D, Aibara, S, Bai, X.C, Rorbach, J, Amunts, A, Ramakrishnan, V. | | 登録日 | 2017-08-08 | | 公開日 | 2017-09-13 | | 最終更新日 | 2023-03-15 | | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | | 主引用文献 | Structures of the human mitochondrial ribosome in native states of assembly.
Nat. Struct. Mol. Biol., 24, 2017
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5OOM
 | | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rRNA | | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Brown, A, Rathore, S, Kimanius, D, Aibara, S, Bai, X.C, Rorbach, J, Amunts, A, Ramakrishnan, V. | | 登録日 | 2017-08-08 | | 公開日 | 2017-09-13 | | 最終更新日 | 2023-03-15 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | Structures of the human mitochondrial ribosome in native states of assembly.
Nat. Struct. Mol. Biol., 24, 2017
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7SHL
 | | Structure of Xenopus laevis CRL2Lrr1 (State 2) | | 分子名称: | CULLIN_2 domain-containing protein, Elongin-C, Lrr1, ... | | 著者 | Zhou, H, Brown, A. | | 登録日 | 2021-10-09 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure of CRL2Lrr1, the E3 ubiquitin ligase that promotes DNA replication termination in vertebrates.
Nucleic Acids Res., 49, 2021
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7SHK
 | | Structure of Xenopus laevis CRL2Lrr1 (State 1) | | 分子名称: | CULLIN_2 domain-containing protein, Elongin-C, Lrr1, ... | | 著者 | Zhou, H, Brown, A. | | 登録日 | 2021-10-09 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of CRL2Lrr1, the E3 ubiquitin ligase that promotes DNA replication termination in vertebrates.
Nucleic Acids Res., 49, 2021
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8J07
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8GLV
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8D3C
 | | VWF tubule derived from monomeric D1-A1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand factor | | 著者 | Anderson, J.R, Li, J, Springer, T.A, Brown, A. | | 登録日 | 2022-06-01 | | 公開日 | 2022-07-06 | | 最終更新日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structures of VWF tubules before and after concatemerization reveal a mechanism of disulfide bond exchange.
Blood, 140, 2022
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8D3D
 | | VWF tubule derived from dimeric D1-A1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand factor | | 著者 | Anderson, J.R, Li, J, Springer, T.A, Brown, A. | | 登録日 | 2022-06-01 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structures of VWF tubules before and after concatemerization reveal a mechanism of disulfide bond exchange.
Blood, 140, 2022
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8SH7
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8F5P
 | | Structure of Leishmania tarentolae IFT-A (state 2) | | 分子名称: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 122B, putative, ... | | 著者 | Zhou, H, Brown, A. | | 登録日 | 2022-11-14 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Mechanism of IFT-A polymerization into trains for ciliary transport.
Cell, 185, 2022
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