2AHB

X-ray crystal structure of R46A,R161A mutant of Mycobacterium tuberculosis FabH

Summary for 2AHB

Entry DOI	10.2210/pdb2ahb/pdb
Related	1HZP 1M1M
Descriptor	Beta- ketoacyl-ACP synthase III (2 entities in total)
Functional Keywords	3-oxoacyl-[acyl-carrier-protein] synthase iii, beta-ketoacyl-acyl carrier protein synthase iii, mtfabh, fabh, transferase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	73933.28
Authors	Brown, A.K.,Sridharan, S.,Kremer, L.,Lindenberg, S.,Dover, L.G.,Sacchettini, J.C.,Besra, G.S. (deposition date: 2005-07-27, release date: 2005-08-23, Last modification date: 2023-08-23)
Primary citation	Brown, A.K.,Sridharan, S.,Kremer, L.,Lindenberg, S.,Dover, L.G.,Sacchettini, J.C.,Besra, G.S. Probing the Mechanism of the Mycobacterium tuberculosis {beta}-Ketoacyl-Acyl Carrier Protein Synthase III mtFabH: FACTORS INFLUENCING CATALYSIS AND SUBSTRATE SPECIFICITY J.Biol.Chem., 280:32539-32547, 2005 Cited by PubMed: 16040614 DOI: 10.1074/jbc.M413216200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation