2AHB
X-ray crystal structure of R46A,R161A mutant of Mycobacterium tuberculosis FabH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta- ketoacyl-ACP synthase III | polymer | 356 | 36966.6 | 2 | UniProt (P0A574) Pfam (PF08545) Pfam (PF08541) UniProt (by SIFTS) (P9WNG3) | Mycobacterium tuberculosis | 3-oxoacyl-[acyl-carrier-protein] synthase III, KAS III, MtFabH |
| 2 | C, D (A, B) | water | water | 18.0 | 237 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 335 (UniProt: P0A574)
| PDB | External Database | Details |
|---|---|---|
| Met -20 | - | cloning artifact |
| Gly -19 | - | cloning artifact |
| Ser -18 | - | cloning artifact |
| Ser -17 | - | cloning artifact |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| Ser -10 | - | cloning artifact |
| Ser -9 | - | cloning artifact |
| Gly -8 | - | cloning artifact |
| Leu -7 | - | cloning artifact |
| Val -6 | - | cloning artifact |
| Pro -5 | - | cloning artifact |
| Arg -4 | - | cloning artifact |
| Gly -3 | - | cloning artifact |
| Ser -2 | - | cloning artifact |
| Val -1 | - | cloning artifact |
| Cys 0 | - | cloning artifact |
| Ala 46 | Arg 46 | engineered mutation |
| Ala 161 | Arg 161 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 73933.3 | |
| All* | Total formula weight | 73933.3 |
