1SXH
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![BU of 1sxh by Molmil](/molmil-images/mine/1sxh) | apo structure of B. megaterium transcription regulator | Descriptor: | Glucose-resistance amylase regulator | Authors: | Schumacher, M.A, Allen, G.S, Diel, M, Seidel, G, Hillen, W, Brennan, R.G. | Deposit date: | 2004-03-30 | Release date: | 2004-10-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural studies on the apo transcription factor form B. megaterium Cell(Cambridge,Mass.), 118, 2004
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1UPF
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![BU of 1upf by Molmil](/molmil-images/mine/1upf) | STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE, MUTANT C128V BOUND TO THE DRUG 5-FLUOROURACIL | Descriptor: | 5-FLUOROURACIL, SULFATE ION, URACIL PHOSPHORIBOSYLTRANSFERASE | Authors: | Schumacher, M.A, Carter, D, Scott, D, Roos, D, Ullman, B, Brennan, R.G. | Deposit date: | 1998-06-17 | Release date: | 1999-06-22 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding. EMBO J., 17, 1998
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1UPU
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![BU of 1upu by Molmil](/molmil-images/mine/1upu) | STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE, MUTANT C128V, BOUND TO PRODUCT URIDINE-1-MONOPHOSPHATE (UMP) | Descriptor: | PHOSPHATE ION, URACIL PHOSPHORIBOSYLTRANSFERASE, URIDINE-5'-MONOPHOSPHATE | Authors: | Schumacher, M.A, Carter, D, Scott, D, Roos, D, Ullman, B, Brennan, R.G. | Deposit date: | 1998-04-16 | Release date: | 1999-05-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding. EMBO J., 17, 1998
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1VPW
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![BU of 1vpw by Molmil](/molmil-images/mine/1vpw) | STRUCTURE OF THE PURR MUTANT, L54M, BOUND TO HYPOXANTHINE AND PURF OPERATOR DNA | Descriptor: | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), HYPOXANTHINE, PURINE REPRESSOR | Authors: | Arvidson, D.N, Lu, F, Faber, C, Zalkin, H, Brennan, R.G. | Deposit date: | 1998-02-27 | Release date: | 1998-06-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The structure of PurR mutant L54M shows an alternative route to DNA kinking. Nat.Struct.Biol., 5, 1998
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1SDL
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![BU of 1sdl by Molmil](/molmil-images/mine/1sdl) | CROSS-LINKED, CARBONMONOXY HEMOGLOBIN A | Descriptor: | 1,3,5-BENZENETRICARBOXYLIC ACID, CARBON MONOXIDE, HEMOGLOBIN A, ... | Authors: | Schumacher, M.A, Dixon, M.M, Kluger, R, Jones, R.T, Brennan, R.G. | Deposit date: | 1996-02-26 | Release date: | 1996-08-01 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Allosteric transition intermediates modelled by crosslinked haemoglobins. Nature, 375, 1995
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1BOW
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![BU of 1bow by Molmil](/molmil-images/mine/1bow) | MULTIDRUG-BINDING DOMAIN OF TRANSCRIPTION ACTIVATOR BMRR (APO FORM) | Descriptor: | MANGANESE (II) ION, MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR BMRR | Authors: | Zheleznova, E.E, Markham, P.N, Neyfakh, A.A, Brennan, R.G. | Deposit date: | 1998-08-06 | Release date: | 1999-08-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter. Cell(Cambridge,Mass.), 96, 1999
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1BD4
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![BU of 1bd4 by Molmil](/molmil-images/mine/1bd4) | UPRT-URACIL COMPLEX | Descriptor: | PHOSPHATE ION, URACIL, URACIL PHOSPHORIBOSYLTRANSFERASE | Authors: | Schumacher, M.A, Carter, D, Scott, D, Roos, D, Ullman, B, Brennan, R.G. | Deposit date: | 1998-05-12 | Release date: | 1999-05-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding. EMBO J., 17, 1998
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1DH3
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![BU of 1dh3 by Molmil](/molmil-images/mine/1dh3) | |
1DBR
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![BU of 1dbr by Molmil](/molmil-images/mine/1dbr) | HYPOXANTHINE GUANINE XANTHINE | Descriptor: | HYPOXANTHINE GUANINE XANTHINE PHOSPHORIBOSYLTRANSFERASE, MAGNESIUM ION | Authors: | Schumacher, M.A, Carter, D, Roos, D, Ullman, B, Brennan, R.G. | Deposit date: | 1996-02-13 | Release date: | 1997-12-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of Toxoplasma gondii HGXPRTase reveal the catalytic role of a long flexible loop. Nat.Struct.Biol., 3, 1996
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1BD3
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![BU of 1bd3 by Molmil](/molmil-images/mine/1bd3) | STRUCTURE OF THE APO URACIL PHOSPHORIBOSYLTRANSFERASE, 2 MUTANT C128V | Descriptor: | PHOSPHATE ION, URACIL PHOSPHORIBOSYLTRANSFERASE | Authors: | Schumacher, M.A, Carter, D, Scott, D, Roos, D, Ullman, B, Brennan, R.G. | Deposit date: | 1998-05-12 | Release date: | 1999-05-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding. EMBO J., 17, 1998
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1DBQ
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![BU of 1dbq by Molmil](/molmil-images/mine/1dbq) | DNA-BINDING REGULATORY PROTEIN | Descriptor: | MAGNESIUM ION, PURINE REPRESSOR | Authors: | Schumacher, M.A, Choi, K.Y, Lu, F, Zalkin, H, Brennan, R.G. | Deposit date: | 1996-02-13 | Release date: | 1996-12-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mechanism of corepressor-mediated specific DNA binding by the purine repressor. Cell(Cambridge,Mass.), 83, 1995
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1ON1
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![BU of 1on1 by Molmil](/molmil-images/mine/1on1) | Bacillus Subtilis Manganese Transport Regulator (Mntr) Bound To Manganese, AB Conformation. | Descriptor: | MANGANESE (II) ION, Transcriptional regulator mntR | Authors: | Glasfeld, A, Guedon, E, Helmann, J.D, Brennan, R.G. | Deposit date: | 2003-02-26 | Release date: | 2003-07-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure of the Manganese-Bound Manganese Transport Regulator of Bacillus subtilis Nat.Struct.Biol., 10, 2003
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1ON2
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![BU of 1on2 by Molmil](/molmil-images/mine/1on2) | Bacillus subtilis Manganese Transport Regulator (MntR), D8M Mutant, Bound to Manganese | Descriptor: | MANGANESE (II) ION, Transcriptional regulator mntR | Authors: | Glasfeld, A, Guedon, E, Helmann, J.D, Brennan, R.G. | Deposit date: | 2003-02-26 | Release date: | 2003-07-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Structure of the Manganese-Bound Manganese Transport Regulator of Bacillus subtilis Nat.Struct.Biol., 10, 2003
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1QB7
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![BU of 1qb7 by Molmil](/molmil-images/mine/1qb7) | CRYSTAL STRUCTURES OF ADENINE PHOSPHORIBOSYLTRANSFERASE FROM LEISHMANIA DONOVANI. | Descriptor: | ADENINE, ADENINE PHOSPHORIBOSYLTRANSFERASE, CITRIC ACID, ... | Authors: | Phillips, C.L, Ullman, B, Brennan, R.G, Hill, C.P. | Deposit date: | 1999-04-30 | Release date: | 1999-07-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani. EMBO J., 18, 1999
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1QVU
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![BU of 1qvu by Molmil](/molmil-images/mine/1qvu) | |
1QVT
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![BU of 1qvt by Molmil](/molmil-images/mine/1qvt) | |
1QCC
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![BU of 1qcc by Molmil](/molmil-images/mine/1qcc) | CRYSTAL STRUCTURES OF ADENINE PHOSPHORIBOSYLTRANSFERASE FROM LEISHMANIA DONOVANI | Descriptor: | ADENINE PHOSPHORIBOSYLTRANSFERASE, CITRIC ACID | Authors: | Phillips, C.L, Ullman, B, Brennan, R.G, Hill, C.P. | Deposit date: | 1999-05-01 | Release date: | 1999-07-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani. EMBO J., 18, 1999
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1PNR
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![BU of 1pnr by Molmil](/molmil-images/mine/1pnr) | PURINE REPRESSOR-HYPOXANTHINE-PURF-OPERATOR COMPLEX | Descriptor: | DNA (5'-D(*AP*AP*CP*GP*AP*AP*AP*AP*CP*GP*TP*TP*TP*TP*CP*GP*T )-3'), HYPOXANTHINE, PROTEIN (PURINE REPRESSOR) | Authors: | Schumacher, M.A, Choi, K.Y, Zalkin, H, Brennan, R.G. | Deposit date: | 1995-03-29 | Release date: | 1995-11-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices. Science, 266, 1994
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1QCD
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![BU of 1qcd by Molmil](/molmil-images/mine/1qcd) | CRYSTAL STRUCTURES OF ADENINE PHOSPHORIBOSYLTRANSFERASE FROM LEISHMANIA DONOVANI | Descriptor: | ADENINE PHOSPHORIBOSYLTRANSFERASE, SULFATE ION | Authors: | Phillips, C.L, Ullman, B, Brennan, R.G, Hill, C.P. | Deposit date: | 1999-05-01 | Release date: | 1999-07-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani. EMBO J., 18, 1999
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4LD5
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![BU of 4ld5 by Molmil](/molmil-images/mine/4ld5) | |
4L9J
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![BU of 4l9j by Molmil](/molmil-images/mine/4l9j) | |
4L9T
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![BU of 4l9t by Molmil](/molmil-images/mine/4l9t) | |
4LLN
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![BU of 4lln by Molmil](/molmil-images/mine/4lln) | Crystal structure of S. aureus MepR-DNA complex | Descriptor: | MepR, Palindromized mepR operator sequence | Authors: | Birukou, I, Brennan, R.G. | Deposit date: | 2013-07-09 | Release date: | 2014-05-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.842 Å) | Cite: | Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR. Nucleic Acids Res., 42, 2014
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4L9N
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![BU of 4l9n by Molmil](/molmil-images/mine/4l9n) | |
4LLL
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![BU of 4lll by Molmil](/molmil-images/mine/4lll) | Crystal structure of S. aureus MepR-DNA complex | Descriptor: | MepR, Palindromized mepR operator sequence | Authors: | Birukou, I, Brennan, R.G. | Deposit date: | 2013-07-09 | Release date: | 2014-05-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.036 Å) | Cite: | Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR. Nucleic Acids Res., 42, 2014
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