4L9N

Crystal structure of MepR A103V mutant from multidrug resistant S. aureus clinical isolate

Summary for 4L9N

Entry DOI	10.2210/pdb4l9n/pdb
Related	4L9J 4L9T 4L9V 4LD5
Descriptor	MepR, SULFATE ION (3 entities in total)
Functional Keywords	wing-helix-turn-helix, whth, transcription repression, transcription
Biological source	Staphylococcus aureus
Total number of polymer chains	2
Total formula weight	34194.54
Authors	Birukou, I.,Brennan, R.G. (deposition date: 2013-06-18, release date: 2013-09-11, Last modification date: 2024-02-28)
Primary citation	Birukou, I.,Tonthat, N.K.,Seo, S.M.,Schindler, B.D.,Kaatz, G.W.,Brennan, R.G. The molecular mechanisms of allosteric mutations impairing MepR repressor function in multidrug-resistant strains of Staphylococcus aureus. MBio, 4:e00528-e00513, 2013 Cited by PubMed: 23982071 DOI: 10.1128/mBio.00528-13 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation