1QVU
Crystal structure of the multidrug binding transcriptional repressor QacR bound to two drugs: ethidium and proflavine
Summary for 1QVU
Entry DOI | 10.2210/pdb1qvu/pdb |
Related | 1JT0 1JT6 1JTX 1JTY 1JUS 1QVT |
Descriptor | Transcriptional regulator qacR, ETHIDIUM, PROFLAVIN (3 entities in total) |
Functional Keywords | qacr, multidrug binding protein, transcription, repressor, cooperative dna binding |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 4 |
Total formula weight | 92584.00 |
Authors | Schumacher, M.A.,Miller, M.C.,Brennan, R.G. (deposition date: 2003-08-28, release date: 2004-08-03, Last modification date: 2023-08-16) |
Primary citation | Schumacher, M.A.,Miller, M.C.,Brennan, R.G. Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein Embo J., 23:2923-2930, 2004 Cited by PubMed: 15257299DOI: 10.1038/sj.emboj.7600288 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.96 Å) |
Structure validation
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