1QVU

Crystal structure of the multidrug binding transcriptional repressor QacR bound to two drugs: ethidium and proflavine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, D, A, E	Transcriptional regulator qacR	polymer	194	23015.1	4	UniProt (P0A0N4) Pfam (PF00440) Pfam (PF08360) In PDB	Staphylococcus aureus
2	A	ETHIDIUM	non-polymer		314.4	1	Chemie (ET)
3	A	PROFLAVIN	non-polymer		209.2	1	Chemie (PRL)

Sequence modifications

B, D, A, E: 1 - 188 (UniProt: P0A0N4)

PDB	External Database	Details
Ser 141	Cys 141	conflict
His 189	-	expression tag
His 190	-	expression tag
His 191	-	expression tag
His 192	-	expression tag
His 193	-	expression tag
His 194	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	92060.4
Non-Polymers*	Number of molecules	2
	Total formula weight	523.7
All*	Total formula weight	92584.0

*Water molecules are not included.