1QVU
Crystal structure of the multidrug binding transcriptional repressor QacR bound to two drugs: ethidium and proflavine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (B, D, A, E) | Transcriptional regulator qacR | polymer | 194 | 23015.1 | 4 | UniProt (P0A0N4) Pfam (PF00440) Pfam (PF08360) | Staphylococcus aureus | |
| 2 | E (A) | ETHIDIUM | non-polymer | 314.4 | 1 | Chemie (ET) | |||
| 3 | F (A) | PROFLAVIN | non-polymer | 209.2 | 1 | Chemie (PRL) |
Sequence modifications
B, D, A, E: 1 - 188 (UniProt: P0A0N4)
| PDB | External Database | Details |
|---|---|---|
| Ser 141 | Cys 141 | conflict |
| His 189 | - | expression tag |
| His 190 | - | expression tag |
| His 191 | - | expression tag |
| His 192 | - | expression tag |
| His 193 | - | expression tag |
| His 194 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 92060.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 523.7 | |
| All* | Total formula weight | 92584.0 |
