1UPU

STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE, MUTANT C128V, BOUND TO PRODUCT URIDINE-1-MONOPHOSPHATE (UMP)

Summary for 1UPU
DescriptorURACIL PHOSPHORIBOSYLTRANSFERASE, PHOSPHATE ION, URIDINE-5'-MONOPHOSPHATE, ... (4 entities in total)
Functional Keywordstransferase, glycosyltransferase, phosphoribosyltransferase
Biological sourceToxoplasma gondii
Total number of polymer chains4
Total formula weight103848.66
Authors
Schumacher, M.A.,Carter, D.,Scott, D.,Roos, D.,Ullman, B.,Brennan, R.G. (deposition date: 1998-04-16, release date: 1999-05-11, Last modification date: 2011-07-13)
Primary citationBrennan, R.G.,Carter, D.,Roos, D.S.,Schumacher, M.A.,Scott, D.M.,Ullman, B.
Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.
EMBO J., 17:3219-3232, 1998
PubMed: 9628859
DOI: 110.1093/emboj/17.12.3219
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation
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PDB entries from 2021-06-16