1UPU
STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE, MUTANT C128V, BOUND TO PRODUCT URIDINE-1-MONOPHOSPHATE (UMP)
Summary for 1UPU
| Entry DOI | 10.2210/pdb1upu/pdb |
| Descriptor | URACIL PHOSPHORIBOSYLTRANSFERASE, PHOSPHATE ION, URIDINE-5'-MONOPHOSPHATE, ... (4 entities in total) |
| Functional Keywords | transferase, glycosyltransferase, phosphoribosyltransferase |
| Biological source | Toxoplasma gondii |
| Total number of polymer chains | 4 |
| Total formula weight | 103848.66 |
| Authors | Schumacher, M.A.,Carter, D.,Scott, D.,Roos, D.,Ullman, B.,Brennan, R.G. (deposition date: 1998-04-16, release date: 1999-05-11, Last modification date: 2024-02-14) |
| Primary citation | Schumacher, M.A.,Carter, D.,Scott, D.M.,Roos, D.S.,Ullman, B.,Brennan, R.G. Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding. EMBO J., 17:3219-3232, 1998 Cited by PubMed: 9628859DOI: 10.1093/emboj/17.12.3219 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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