1UPU
STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE, MUTANT C128V, BOUND TO PRODUCT URIDINE-1-MONOPHOSPHATE (UMP)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (D, C, B, A) | URACIL PHOSPHORIBOSYLTRANSFERASE | polymer | 224 | 25543.0 | 4 | UniProt (Q26998) Pfam (PF14681) | Toxoplasma gondii | UPRTASE |
| 2 | E, G, I, K (D, C, B, A) | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
| 3 | F, H, J, L (D, C, B, A) | URIDINE-5'-MONOPHOSPHATE | non-polymer | 324.2 | 4 | Chemie (U5P) | |||
| 4 | M, N, O, P (D, C, B, A) | water | water | 18.0 | 400 | Chemie (HOH) |
Sequence modifications
D, C, B, A: 21 - 244 (UniProt: Q26998)
| PDB | External Database | Details |
|---|---|---|
| Gln 84 | Glu 84 | conflict |
| Val 128 | Cys 128 | engineered mutation |
| Glu 157 | Asp 157 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 102172.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1676.6 | |
| All* | Total formula weight | 103848.7 |
