Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 175 results

3BTL
DownloadVisualize
BU of 3btl by Molmil
crystal structure of QacR(E58Q) bound to malachite green
Descriptor: HTH-type transcriptional regulator qacR, MALACHITE GREEN, SULFATE ION
Authors:Schumacher, M.A, Schuman, J.T, Brennan, R.G.
Deposit date:2007-12-28
Release date:2008-08-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:QacR-cation recognition is mediated by a redundancy of residues capable of charge neutralization
Biochemistry, 47, 2008
3D6Z
DownloadVisualize
BU of 3d6z by Molmil
Crystal structure of R275E mutant of BMRR bound to DNA and rhodamine
Descriptor: BMR promoter DNA, GLYCEROL, Multidrug-efflux transporter 1 regulator, ...
Authors:Newberry, K.J, Brennan, R.G.
Deposit date:2008-05-20
Release date:2008-08-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of BmrR-Drug Complexes Reveal a Rigid Multidrug Binding Pocket and Transcription Activation through Tyrosine Expulsion
J.Biol.Chem., 283, 2008
3D70
DownloadVisualize
BU of 3d70 by Molmil
Crystal structure of E253A mutant of BMRR bound to 22-bp oligonucleotide
Descriptor: BMR promoter DNA, GLYCEROL, IMIDAZOLE, ...
Authors:Newberry, K.J, Brennan, R.G.
Deposit date:2008-05-20
Release date:2008-08-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of BmrR-Drug Complexes Reveal a Rigid Multidrug Binding Pocket and Transcription Activation through Tyrosine Expulsion
J.Biol.Chem., 283, 2008
5HJZ
DownloadVisualize
BU of 5hjz by Molmil
Structure of M. tuberculosis MazF-mt1 (Rv2801c) in complex with RNA
Descriptor: Endoribonuclease MazF9, RNA (5'-R(*CP*AP*UP*C)-D(P*U)-R(P*AP*CP*CP*UP*GP*A)-3')
Authors:Yen, T.J, Brennan, R.G.
Deposit date:2016-01-13
Release date:2017-01-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.976 Å)
Cite:Structure of M. tuberculosis MazF-mt1 (Rv2801c) in complex with RNA
To Be Published
5HK3
DownloadVisualize
BU of 5hk3 by Molmil
Crystal structure of M. tuberculosis MazF-mt3 T52D-F62D mutant in complex with DNA
Descriptor: DNA (5'-D(*AP*GP*UP*CP*UP*CP*CP*UP*UP*UP*C)-3'), Endoribonuclease MazF6
Authors:Yen, T.J, Brennan, R.G.
Deposit date:2016-01-13
Release date:2017-01-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Crystal structure of M. tuberculosis MazF-mt3 T52D-F62D mutant in complex with DNA
To Be Published
5HKC
DownloadVisualize
BU of 5hkc by Molmil
Crystal structure of M. tuberculosis MazF-mt3 T52D-F62D mutant in complex with 8-mer RNA
Descriptor: Endoribonuclease MazF6, RNA (5'-R(*GP*UP*C)-D(P*U)-R(P*CP*CP*UP*A)-3')
Authors:Yen, T.J, Brennan, R.G.
Deposit date:2016-01-14
Release date:2017-01-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystal structure of M. tuberculosis MazF-mt3 T52D-F62D mutant in complex with 8-mer RNA
To Be Published
5HK0
DownloadVisualize
BU of 5hk0 by Molmil
Crystal structure of M. tuberculosis MazF-mt3 (Rv1991c) in complex with RNA
Descriptor: Endoribonuclease MazF6, RNA (5'-R(*AP*GP*UP*C)-D(P*U)-R(P*CP*CP*UP*UP*UP*C)-3')
Authors:Yen, T.J, Brennan, R.G.
Deposit date:2016-01-13
Release date:2017-01-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of M. tuberculosis MazF-mt3 (Rv1991c) in complex with RNA
To Be Published
5HUS
DownloadVisualize
BU of 5hus by Molmil
Structure of Candida albicans trehalose synthase regulatory protein C-terminal domain
Descriptor: trehalose synthase regulatory protein
Authors:Miao, Y, Brennan, R.G.
Deposit date:2016-01-27
Release date:2017-05-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.751 Å)
Cite:Structure of Candida albicans trehalose synthase regulatory protein C-terminal domain
To Be Published
5HUU
DownloadVisualize
BU of 5huu by Molmil
Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and glucose-6-phosphate
Descriptor: 6-O-phosphono-alpha-D-glucopyranose, Alpha,alpha-trehalose-phosphate synthase [UDP-forming], URIDINE-5'-DIPHOSPHATE
Authors:Miao, Y, Brennan, R.G.
Deposit date:2016-01-27
Release date:2017-05-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.
MBio, 8, 2017
5HVM
DownloadVisualize
BU of 5hvm by Molmil
Structure of Aspergillus fumigatus trehalose-6-phosphate synthase A in complex with UDP and validoxylamine A
Descriptor: (1S,2S,3R,6S)-4-(HYDROXYMETHYL)-6-{[(1S,2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-(HYDROXYMETHYL)CYCLOHEXYL]AMINO}CYCLOHEX-4-ENE-1,2,3-TRIOL, Alpha,alpha-trehalose-phosphate synthase (UDP-forming), URIDINE-5'-DIPHOSPHATE
Authors:Miao, Y, Brennan, R.G.
Deposit date:2016-01-28
Release date:2017-05-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.815 Å)
Cite:Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.
MBio, 8, 2017
5HUT
DownloadVisualize
BU of 5hut by Molmil
Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP-glucose
Descriptor: Alpha,alpha-trehalose-phosphate synthase [UDP-forming], PENTAETHYLENE GLYCOL, SODIUM ION, ...
Authors:Miao, Y, Brennan, R.G.
Deposit date:2016-01-27
Release date:2017-05-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.
MBio, 8, 2017
5HVL
DownloadVisualize
BU of 5hvl by Molmil
Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP and validoxylamine A
Descriptor: (1S,2S,3R,6S)-4-(HYDROXYMETHYL)-6-{[(1S,2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-(HYDROXYMETHYL)CYCLOHEXYL]AMINO}CYCLOHEX-4-ENE-1,2,3-TRIOL, Alpha,alpha-trehalose-phosphate synthase [UDP-forming], SULFATE ION, ...
Authors:Miao, Y, Brennan, R.G.
Deposit date:2016-01-28
Release date:2017-05-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.796 Å)
Cite:Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.
MBio, 8, 2017
5HVO
DownloadVisualize
BU of 5hvo by Molmil
Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A
Descriptor: (1S,2S,3R,6S)-4-(HYDROXYMETHYL)-6-{[(1S,2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-(HYDROXYMETHYL)CYCLOHEXYL]AMINO}CYCLOHEX-4-ENE-1,2,3-TRIOL, Alpha,alpha-trehalose-phosphate synthase (UDP-forming), URIDINE-5'-DIPHOSPHATE
Authors:Miao, Y, Brennan, R.G.
Deposit date:2016-01-28
Release date:2017-05-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.467 Å)
Cite:Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.
MBio, 8, 2017
5HUV
DownloadVisualize
BU of 5huv by Molmil
Structure of Candida albicans trehalose-6-phosphate synthase E341R/E346R in complex with UDP-glucose
Descriptor: Alpha,alpha-trehalose-phosphate synthase [UDP-forming], URIDINE-5'-DIPHOSPHATE-GLUCOSE
Authors:Miao, Y, Brennan, R.G.
Deposit date:2016-01-27
Release date:2017-05-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Structure of Candida albicans trehalose-6-phosphate synthase E341R/E346R in complex with UDP-glucose
To Be Published
5FFZ
DownloadVisualize
BU of 5ffz by Molmil
S. aureus MepR bound to ethidium bromide
Descriptor: ETHIDIUM, MarR family regulatory protein, POTASSIUM ION
Authors:Birukou, I, Newman, C.E, Brennan, R.G.
Deposit date:2015-12-19
Release date:2016-12-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.585 Å)
Cite:S. aureus MepR bound to ethidium bromide
To Be Published
5FFX
DownloadVisualize
BU of 5ffx by Molmil
S. aureus MepR G34K Mutant
Descriptor: GLYCEROL, MarR family regulatory protein, SULFATE ION
Authors:Newman, C.E, Birukou, I, Brennan, R.G.
Deposit date:2015-12-19
Release date:2016-12-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:S. aureus MepR G34K Mutant
To Be Published
1JT0
DownloadVisualize
BU of 1jt0 by Molmil
Crystal structure of a cooperative QacR-DNA complex
Descriptor: HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, QACA operator, SULFATE ION
Authors:Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G.
Deposit date:2001-08-20
Release date:2002-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR.
EMBO J., 21, 2002
1JTX
DownloadVisualize
BU of 1jtx by Molmil
Crystal structure of the multidrug binding transcriptional regulator QacR bound to crystal violet
Descriptor: CRYSTAL VIOLET, HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, SULFATE ION
Authors:Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G.
Deposit date:2001-08-22
Release date:2001-12-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural mechanisms of QacR induction and multidrug recognition.
Science, 294, 2001
1KQ2
DownloadVisualize
BU of 1kq2 by Molmil
Crystal Structure of an Hfq-RNA Complex
Descriptor: 5'-R(*AP*UP*UP*UP*UP*UP*G)-3', Host factor for Q beta
Authors:Schumacher, M.A, Pearson, R.F, Moller, T, Valentin-Hansen, P, Brennan, R.G.
Deposit date:2002-01-03
Release date:2002-07-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like protein.
EMBO J., 21, 2002
1KQ1
DownloadVisualize
BU of 1kq1 by Molmil
1.55 A Crystal structure of the pleiotropic translational regulator, Hfq
Descriptor: ACETIC ACID, Host Factor for Q beta
Authors:Schumacher, M.A, Pearson, R.F, Moller, T, Valentin-Hansen, P, Brennan, R.G.
Deposit date:2002-01-03
Release date:2002-07-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like protein.
EMBO J., 21, 2002
1JHZ
DownloadVisualize
BU of 1jhz by Molmil
Purine Repressor Mutant Corepressor Binding Domain Structure
Descriptor: MAGNESIUM ION, PURINE NUCLEOTIDE SYNTHESIS REPRESSOR
Authors:Huffman, J.L, Lu, F, Zalkin, H, Brennan, R.G.
Deposit date:2001-06-28
Release date:2002-02-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor.
Biochemistry, 41, 2002
1JTY
DownloadVisualize
BU of 1jty by Molmil
Crystal structure of the multidrug binding transcriptional regulator QacR bound to ethidium
Descriptor: ETHIDIUM, HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, SULFATE ION
Authors:Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G.
Deposit date:2001-08-22
Release date:2001-12-12
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Structural mechanisms of QacR induction and multidrug recognition.
Science, 294, 2001
1JUM
DownloadVisualize
BU of 1jum by Molmil
Crystal structure of the multidrug binding transcriptional repressor QacR bound to the natural drug berberine
Descriptor: BERBERINE, HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, SULFATE ION
Authors:Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G.
Deposit date:2001-08-24
Release date:2001-12-12
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Structural mechanisms of QacR induction and multidrug recognition.
Science, 294, 2001
1JH9
DownloadVisualize
BU of 1jh9 by Molmil
PURINE REPRESSOR MUTANT-HYPOXANTHINE-PURF OPERATOR COMPLEX
Descriptor: 5'-D(*AP*AP*CP*GP*AP*AP*AP*AP*CP*GP*TP*TP*TP*TP*CP*GP*T)-3', HYPOXANTHINE, PHOSPHATE ION, ...
Authors:Huffman, J.L, Lu, F, Zalkin, H, Brennan, R.G.
Deposit date:2001-06-27
Release date:2002-02-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor.
Biochemistry, 41, 2002
1LIJ
DownloadVisualize
BU of 1lij by Molmil
STRUCTURE OF T. GONDII ADENOSINE KINASE BOUND TO PRODRUG 2 7-IODOTUBERCIDIN AND AMP-PCP
Descriptor: 2-RIBOFURANOSYL-3-IODO-2,3-DIHYDRO-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Schumacher, M.A, Scott, D.M, Mathews, I.I, Ealick, S.E, Roos, D.S, Ullman, B, Brennan, R.G.
Deposit date:2002-04-17
Release date:2002-05-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
J.Mol.Biol., 298, 2000

221371

건을2024-06-19부터공개중

PDB statisticsPDBj update infoContact PDBjnumon