1JUS

Crystal structure of the multidrug binding transcriptional repressor QacR bound to rhodamine 6G

Summary for 1JUS

Entry DOI	10.2210/pdb1jus/pdb
Related	1JT0 1JT6 1JTX 1JTY 1JUM 1JUP
Descriptor	HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, SULFATE ION, RHODAMINE 6G, ... (4 entities in total)
Functional Keywords	multidrug recognition, s. aureus, qacr, rhodamine 6g, cationic lipophilic drugs, transcription
Biological source	Staphylococcus aureus
Total number of polymer chains	4
Total formula weight	95147.83
Authors	Schumacher, M.A.,Miller, M.C.,Grkovic, S.,Brown, M.H.,Skurray, R.A.,Brennan, R.G. (deposition date: 2001-08-27, release date: 2001-12-12, Last modification date: 2021-10-27)
Primary citation	Schumacher, M.A.,Miller, M.C.,Grkovic, S.,Brown, M.H.,Skurray, R.A.,Brennan, R.G. Structural mechanisms of QacR induction and multidrug recognition. Science, 294:2158-2163, 2001 Cited by PubMed: 11739955 DOI: 10.1126/science.1066020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.84 Å)

Structure validation