1JTY

Crystal structure of the multidrug binding transcriptional regulator QacR bound to ethidium

Summary for 1JTY

Entry DOI	10.2210/pdb1jty/pdb
Related	1JT0 1JT6 1JTX 1JUM 1JUP 1JUS
Descriptor	HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, SULFATE ION, ETHIDIUM, ... (4 entities in total)
Functional Keywords	multidrug binding, multidrug recognition mechanism, cationic lipophilic drugs, qacr, qaca, repressor, transcription
Biological source	Staphylococcus aureus
Total number of polymer chains	4
Total formula weight	93879.57
Authors	Schumacher, M.A.,Miller, M.C.,Grkovic, S.,Brown, M.H.,Skurray, R.A.,Brennan, R.G. (deposition date: 2001-08-22, release date: 2001-12-12, Last modification date: 2023-08-16)
Primary citation	Schumacher, M.A.,Miller, M.C.,Grkovic, S.,Brown, M.H.,Skurray, R.A.,Brennan, R.G. Structural mechanisms of QacR induction and multidrug recognition. Science, 294:2158-2163, 2001 Cited by PubMed: 11739955 DOI: 10.1126/science.1066020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.97 Å)

Structure validation