4L9N
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4NOY
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4NL2
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4NL3
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4OAY
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![BU of 4oay by Molmil](/molmil-images/mine/4oay) | BldD CTD-c-di-GMP complex | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein | Authors: | Schumacher, M.A, Tschowri, N, Buttner, M, Brennan, R.G. | Deposit date: | 2014-01-06 | Release date: | 2014-11-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development. Cell(Cambridge,Mass.), 158, 2014
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1JLR
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![BU of 1jlr by Molmil](/molmil-images/mine/1jlr) | STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE GTP COMPLEX 2 MUTANT C128V | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, Uracil Phosphoribosyltransferase | Authors: | Schumacher, M.A, Bashor, C.J, Otsu, K, Zu, S, Parry, R, Ulmman, B, Brennan, R.G. | Deposit date: | 2001-07-16 | Release date: | 2002-01-10 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | The structural mechanism of GTP stabilized oligomerization and catalytic activation of the Toxoplasma gondii uracil phosphoribosyltransferase. Proc.Natl.Acad.Sci.USA, 99, 2002
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1JT6
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![BU of 1jt6 by Molmil](/molmil-images/mine/1jt6) | Crystal structure of the multidrug binding protein QacR bound to dequalinium | Descriptor: | DEQUALINIUM, Hypothetical transcriptional regulator IN QACA 5'region, SULFATE ION | Authors: | Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G. | Deposit date: | 2001-08-20 | Release date: | 2001-12-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Structural mechanisms of QacR induction and multidrug recognition. Science, 294, 2001
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1JTX
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![BU of 1jtx by Molmil](/molmil-images/mine/1jtx) | Crystal structure of the multidrug binding transcriptional regulator QacR bound to crystal violet | Descriptor: | CRYSTAL VIOLET, HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, SULFATE ION | Authors: | Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G. | Deposit date: | 2001-08-22 | Release date: | 2001-12-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural mechanisms of QacR induction and multidrug recognition. Science, 294, 2001
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1KQ2
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![BU of 1kq2 by Molmil](/molmil-images/mine/1kq2) | Crystal Structure of an Hfq-RNA Complex | Descriptor: | 5'-R(*AP*UP*UP*UP*UP*UP*G)-3', Host factor for Q beta | Authors: | Schumacher, M.A, Pearson, R.F, Moller, T, Valentin-Hansen, P, Brennan, R.G. | Deposit date: | 2002-01-03 | Release date: | 2002-07-05 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like protein. EMBO J., 21, 2002
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1JFS
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![BU of 1jfs by Molmil](/molmil-images/mine/1jfs) | PURINE REPRESSOR MUTANT-HYPOXANTHINE-PURF OPERATOR COMPLEX | Descriptor: | 5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T)-3', HYPOXANTHINE, PURINE NUCLEOTIDE SYNTHESIS REPRESSOR | Authors: | Huffman, J.L, Lu, F, Zalkin, H, Brennan, R.G. | Deposit date: | 2001-06-21 | Release date: | 2002-02-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor. Biochemistry, 41, 2002
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1JFT
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![BU of 1jft by Molmil](/molmil-images/mine/1jft) | PURINE REPRESSOR MUTANT-HYPOXANTHINE-PURF OPERATOR COMPLEX | Descriptor: | 5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T)-3', HYPOXANTHINE, PHOSPHATE ION, ... | Authors: | Huffman, J.L, Lu, F, Zalkin, H, Brennan, R.G. | Deposit date: | 2001-06-21 | Release date: | 2002-02-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor. Biochemistry, 41, 2002
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1JBG
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![BU of 1jbg by Molmil](/molmil-images/mine/1jbg) | Crystal Structure of MtaN, the Bacillus subtilis Multidrug Transporter Activator, N-terminus | Descriptor: | transcription activator of multidrug-efflux transporter genes mta | Authors: | Godsey, M.H, Neyfakh, A.A, Brennan, R.G. | Deposit date: | 2001-06-04 | Release date: | 2001-11-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structure of MtaN, a global multidrug transporter gene activator. J.Biol.Chem., 276, 2001
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1JLS
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![BU of 1jls by Molmil](/molmil-images/mine/1jls) | STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE URACIL/CPR 2 MUTANT C128V | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Schumacher, M.A, Bashor, C.J, Otsu, K, Zu, S, Parry, R, Ullman, B, Brennan, R.G. | Deposit date: | 2001-07-16 | Release date: | 2002-01-16 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The structural mechanism of GTP stabilized oligomerization and catalytic activation of the Toxoplasma gondii uracil phosphoribosyltransferase. Proc.Natl.Acad.Sci.USA, 99, 2002
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1JT0
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![BU of 1jt0 by Molmil](/molmil-images/mine/1jt0) | Crystal structure of a cooperative QacR-DNA complex | Descriptor: | HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, QACA operator, SULFATE ION | Authors: | Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G. | Deposit date: | 2001-08-20 | Release date: | 2002-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR. EMBO J., 21, 2002
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1LIJ
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![BU of 1lij by Molmil](/molmil-images/mine/1lij) | STRUCTURE OF T. GONDII ADENOSINE KINASE BOUND TO PRODRUG 2 7-IODOTUBERCIDIN AND AMP-PCP | Descriptor: | 2-RIBOFURANOSYL-3-IODO-2,3-DIHYDRO-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Schumacher, M.A, Scott, D.M, Mathews, I.I, Ealick, S.E, Roos, D.S, Ullman, B, Brennan, R.G. | Deposit date: | 2002-04-17 | Release date: | 2002-05-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding. J.Mol.Biol., 298, 2000
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1LIK
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![BU of 1lik by Molmil](/molmil-images/mine/1lik) | STRUCTURE OF T. GONDII ADENOSINE KINASE BOUND TO ADENOSINE | Descriptor: | ADENOSINE, CHLORIDE ION, SULFATE ION, ... | Authors: | Schumacher, M.A, Scott, D.M, Mathews, I.I, Ealick, S.E, Roos, D.S, Ullman, B, Brennan, R.G. | Deposit date: | 2002-04-17 | Release date: | 2002-05-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding. J.Mol.Biol., 298, 2000
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1LII
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![BU of 1lii by Molmil](/molmil-images/mine/1lii) | STRUCTURE OF T. GONDII ADENOSINE KINASE BOUND TO ADENOSINE 2 AND AMP-PCP | Descriptor: | ADENOSINE, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Schumacher, M.A, Scott, D.M, Mathews, I.I, Ealick, S.E, Roos, D.S, Ullman, B, Brennan, R.G. | Deposit date: | 2002-04-17 | Release date: | 2002-05-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding. J.Mol.Biol., 298, 2000
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1JUP
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![BU of 1jup by Molmil](/molmil-images/mine/1jup) | Crystal structure of the multidrug binding transcriptional repressor QacR bound to malachite green | Descriptor: | HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, MALACHITE GREEN, SULFATE ION | Authors: | Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G. | Deposit date: | 2001-08-24 | Release date: | 2001-12-12 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural mechanisms of QacR induction and multidrug recognition. Science, 294, 2001
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1KQ1
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![BU of 1kq1 by Molmil](/molmil-images/mine/1kq1) | 1.55 A Crystal structure of the pleiotropic translational regulator, Hfq | Descriptor: | ACETIC ACID, Host Factor for Q beta | Authors: | Schumacher, M.A, Pearson, R.F, Moller, T, Valentin-Hansen, P, Brennan, R.G. | Deposit date: | 2002-01-03 | Release date: | 2002-07-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like protein. EMBO J., 21, 2002
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1LIO
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![BU of 1lio by Molmil](/molmil-images/mine/1lio) | STRUCTURE OF APO T. GONDII ADENOSINE KINASE | Descriptor: | adenosine kinase | Authors: | Schumacher, M.A, Scott, D.M, Mathews, I.I, Ealick, S.E, Brennan, R.G. | Deposit date: | 2002-04-17 | Release date: | 2002-06-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding. J.Mol.Biol., 298, 2000
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1JUS
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![BU of 1jus by Molmil](/molmil-images/mine/1jus) | Crystal structure of the multidrug binding transcriptional repressor QacR bound to rhodamine 6G | Descriptor: | HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, RHODAMINE 6G, SULFATE ION | Authors: | Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G. | Deposit date: | 2001-08-27 | Release date: | 2001-12-12 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Structural mechanisms of QacR induction and multidrug recognition. Science, 294, 2001
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1JH9
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![BU of 1jh9 by Molmil](/molmil-images/mine/1jh9) | PURINE REPRESSOR MUTANT-HYPOXANTHINE-PURF OPERATOR COMPLEX | Descriptor: | 5'-D(*AP*AP*CP*GP*AP*AP*AP*AP*CP*GP*TP*TP*TP*TP*CP*GP*T)-3', HYPOXANTHINE, PHOSPHATE ION, ... | Authors: | Huffman, J.L, Lu, F, Zalkin, H, Brennan, R.G. | Deposit date: | 2001-06-27 | Release date: | 2002-02-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor. Biochemistry, 41, 2002
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1JHZ
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![BU of 1jhz by Molmil](/molmil-images/mine/1jhz) | Purine Repressor Mutant Corepressor Binding Domain Structure | Descriptor: | MAGNESIUM ION, PURINE NUCLEOTIDE SYNTHESIS REPRESSOR | Authors: | Huffman, J.L, Lu, F, Zalkin, H, Brennan, R.G. | Deposit date: | 2001-06-28 | Release date: | 2002-02-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor. Biochemistry, 41, 2002
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1JTY
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![BU of 1jty by Molmil](/molmil-images/mine/1jty) | Crystal structure of the multidrug binding transcriptional regulator QacR bound to ethidium | Descriptor: | ETHIDIUM, HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, SULFATE ION | Authors: | Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G. | Deposit date: | 2001-08-22 | Release date: | 2001-12-12 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.97 Å) | Cite: | Structural mechanisms of QacR induction and multidrug recognition. Science, 294, 2001
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1JUM
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![BU of 1jum by Molmil](/molmil-images/mine/1jum) | Crystal structure of the multidrug binding transcriptional repressor QacR bound to the natural drug berberine | Descriptor: | BERBERINE, HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, SULFATE ION | Authors: | Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G. | Deposit date: | 2001-08-24 | Release date: | 2001-12-12 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Structural mechanisms of QacR induction and multidrug recognition. Science, 294, 2001
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