Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 36 件
8CR8
DownloadVisualize
BU of 8cr8 by Molmil
human Interleukin-23
分子名称: Interleukin-12 subunit beta, Interleukin-23 subunit alpha, TERBIUM(III) ION, ...
著者Bloch, Y, Savvides, S.N.
登録日2023-03-08
公開日2024-02-07
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
7R3N
DownloadVisualize
BU of 7r3n by Molmil
mouse Interleukin-12 subunit beta - p80 homodimer in space group P21 crystal form 3
分子名称: Interleukin-12 subunit beta, PHOSPHATE ION, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Bloch, Y, Savvides, S.N.
登録日2022-02-07
公開日2022-05-04
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Around she goes: the structure of mouse Interleukin-12 p80
To Be Published
7PUR
DownloadVisualize
BU of 7pur by Molmil
mouse Interleukin-12 subunit beta - p80 homodimer in space group P21 crystal form 2
分子名称: Interleukin-12 subunit beta, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Bloch, Y, Savvides, S.N.
登録日2021-09-30
公開日2021-11-10
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Around she goes: the structure of mouse Interleukin-12 p80
To Be Published
7PNN
DownloadVisualize
BU of 7pnn by Molmil
mVenus released from fusion protein.
分子名称: CHLORIDE ION, mVenus
著者Bloch, Y, Savvides, S.N.
登録日2021-09-07
公開日2021-11-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献mVenus released from fusion protein.
To Be Published
5MZV
DownloadVisualize
BU of 5mzv by Molmil
IL-23:IL-23R:Nb22E11 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Bloch, Y, Savvides, S.N.
登録日2017-02-01
公開日2018-01-03
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12R beta 1.
Immunity, 48, 2018
6SMC
DownloadVisualize
BU of 6smc by Molmil
mouse Interleukin-12 subunit beta - p80 homodimer in space group P1
分子名称: CHLORIDE ION, Interleukin-12 subunit beta, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Bloch, Y, Savvides, S.N.
登録日2019-08-21
公開日2020-09-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Around she goes: the structure of mouse Interleukin-12 p80
To Be Published
8C6Z
DownloadVisualize
BU of 8c6z by Molmil
necrotic enteritis associated Clostridium p. chitinase F8UNI4 in complex with inhibitor bisdionin C
分子名称: 1,1'-PROPANE-1,3-DIYLBIS(3,7-DIMETHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE), CADMIUM ION, COBALT (II) ION, ...
著者Bloch, Y, Savvides, S.N.
登録日2023-01-12
公開日2023-05-31
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Contribution and structural characterization of Chitinases to Clostridium perfringens Pathogenesis in Broilers
To Be Published
8C7M
DownloadVisualize
BU of 8c7m by Molmil
Interleukin 12 receptor subunit beta-1 Fn domains in complex with antagonistic FAb fragment.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, FAb4 Crystal Kappa Light chain, ...
著者Bloch, Y, Savvides, S.N.
登録日2023-01-16
公開日2024-01-31
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8OE4
DownloadVisualize
BU of 8oe4 by Molmil
Cryo-EM structure of a pre-dimerized human IL-23 complete extracellular signaling complex.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, ...
著者Bloch, Y, Felix, J, Savvides, S.N.
登録日2023-03-10
公開日2024-02-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8C7L
DownloadVisualize
BU of 8c7l by Molmil
Serendipitous structure of OmpF contaminant in space group P21.
分子名称: Outer membrane porin F
著者Bloch, Y, Theunissen, S, Savvides, S.N.
登録日2023-01-16
公開日2023-02-22
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (3.52 Å)
主引用文献Serendipitous structure of OmpF contaminant in space group P21.
To Be Published
6SP3
DownloadVisualize
BU of 6sp3 by Molmil
mouse Interleukin-12 subunit beta - p80 homodimer in space group P21 crystal form 1
分子名称: CHLORIDE ION, Interleukin-12 subunit beta, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Bloch, Y, Savvides, S.N.
登録日2019-08-30
公開日2020-09-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Around she goes: the structure of mouse Interleukin-12 p80
To Be Published
7ZXK
DownloadVisualize
BU of 7zxk by Molmil
Human IL-27 in complex with neutralizing SRF388 FAb fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 subunit alpha, Interleukin-27 subunit beta, ...
著者Bloch, Y, Skladanowska, K, Strand, J, Welin, M, Logan, D, Hill, J, Savvides, S.N.
登録日2022-05-21
公開日2022-11-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27.
Cell Rep, 41, 2022
5NJD
DownloadVisualize
BU of 5njd by Molmil
Structure of Interleukin 23 in complex with Briakinumab FAb
分子名称: Briakinumab FAb Heavy chain, Briakinumab FAb Light chain, Interleukin-12 subunit beta, ...
著者Bloch, Y, Savvides, S.N.
登録日2017-03-28
公開日2018-01-03
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12R beta 1.
Immunity, 48, 2018
5MXA
DownloadVisualize
BU of 5mxa by Molmil
Structure of unbound Interleukin-23
分子名称: Interleukin-12 subunit beta, Interleukin-23 subunit alpha, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Bloch, Y, Savvides, S.N.
登録日2017-01-22
公開日2017-12-20
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12R beta 1.
Immunity, 48, 2018
5N2K
DownloadVisualize
BU of 5n2k by Molmil
Structure of unbound Briakinumab FAb
分子名称: 1,2-ETHANEDIOL, Briakinumab FAb heavy chain, Briakinumab FAb light chain
著者Bloch, Y, Savvides, S.N.
登録日2017-02-07
公開日2018-01-03
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.219 Å)
主引用文献Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12R beta 1.
Immunity, 48, 2018
8C7E
DownloadVisualize
BU of 8c7e by Molmil
Serendipitous cyanase structure from Serratia-like contamination
分子名称: CHLORIDE ION, Cyanate hydratase
著者Bloch, Y, Skladanowska, K, Savvides, S.N.
登録日2023-01-14
公開日2023-02-22
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Serendipitous cyanase structure from Serratia-like contamination.
To Be Published
8AD2
DownloadVisualize
BU of 8ad2 by Molmil
Tobacco lectin Nictaba in complex with triacetylchitotriose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Nictaba, ...
著者Bloch, Y, Savvides, S.N.
登録日2022-07-07
公開日2023-01-18
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of the archetypical Nictaba plant lectin reveals the molecular basis for its carbohydrate-binding properties
Biorxiv, 2024
8OVR
DownloadVisualize
BU of 8ovr by Molmil
Clostridium perfringens chitinase CP56_3454 apo form
分子名称: Chitinase B, PIPERAZINE-N,N'-BIS(2-ETHANESULFONIC ACID), SODIUM ION, ...
著者Bloch, Y, Savvides, S.N.
登録日2023-04-26
公開日2023-07-12
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Clostridium perfringens chitinase CP56_3454 apo form
To Be Published
8OYE
DownloadVisualize
BU of 8oye by Molmil
Clostridium perfringens chitinase CP4_3455 E196Q with chitin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitodextrinase, DIMETHYL SULFOXIDE
著者Bloch, Y, Savvides, S.N.
登録日2023-05-04
公開日2023-07-12
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Clostridium perfringens chitinase CP4_3455 E196Q with chitin
To Be Published
8OWF
DownloadVisualize
BU of 8owf by Molmil
Clostridium perfringens chitinase CP4_3455 with chitosan
分子名称: 2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Chitodextrinase, ...
著者Bloch, Y, Savvides, S.N.
登録日2023-04-27
公開日2023-07-12
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Clostridium perfringens chitinase CP4_3455 with chitosan
To Be Published
8OSE
DownloadVisualize
BU of 8ose by Molmil
C. perfringens chitinase CP4_3455 in complex with inhibitor bisdionin C
分子名称: 1,1'-PROPANE-1,3-DIYLBIS(3,7-DIMETHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE), 1,2-ETHANEDIOL, Chitodextrinase, ...
著者Bloch, Y, Savvides, S.N.
登録日2023-04-18
公開日2023-07-12
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献C. perfringens chitinase CP4_3455 in complex with inhibitor bisdionin C
To Be Published
8OTB
DownloadVisualize
BU of 8otb by Molmil
Clostridium perfringens chitinase CP4_3455
分子名称: CHLORIDE ION, Chitodextrinase, DI(HYDROXYETHYL)ETHER, ...
著者Bloch, Y, Savvides, S.N.
登録日2023-04-20
公開日2023-07-12
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Clostridium perfringens chitinase CP4_3455
To Be Published
8QMG
DownloadVisualize
BU of 8qmg by Molmil
Tobacco lectin Nictaba in apo state including I and Eu SAD datasets.
分子名称: Nictaba, ZINC ION
著者Bloch, Y, Savvides, S.N.
登録日2023-09-22
公開日2023-11-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of the archetypical Nictaba plant lectin reveals the molecular basis for its carbohydrate-binding properties
Biorxiv, 2024
6SFF
DownloadVisualize
BU of 6sff by Molmil
mouse Interleukin-12 subunit beta - p80 homodimer in space group I41
分子名称: CHLORIDE ION, Interleukin-12 subunit beta, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Bloch, Y, Savvides, S.N.
登録日2019-08-01
公開日2020-08-26
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Homogeneously N-glycosylated proteins derived from the GlycoDelete HEK293 cell line enable diffraction-quality crystallogenesis.
Acta Crystallogr D Struct Biol, 76, 2020
8PPM
DownloadVisualize
BU of 8ppm by Molmil
IL-12Rb1 neutralizing Fab4, crystal kappa variant
分子名称: Fab4 Light chain, crystal kappa variant, Fab4 heavy chain, ...
著者Bloch, Y, Savvides, S.N.
登録日2023-07-07
公開日2024-02-07
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024

 

12>

226707

件を2024-10-30に公開中

PDB statisticsPDBj update infoContact PDBjnumon