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PDB: 195 results
7K8V
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BU of 7k8v by Molmil
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C110
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C110 Fab Heavy Chain, ...
Authors:Dam, K.A, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7KDE
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BU of 7kde by Molmil
BG505 SOSIP.664 in complex with the V3-targeting rhesus macaque antibody 1485 and human gp120-gp41 interface antibody 8ANC195
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-10-08
Release date:2020-10-28
Last modified:2020-11-04
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch.
Elife, 9, 2020
7K8O
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BU of 7k8o by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C002
Descriptor: C002 Fab Heavy Chain, C002 Fab Light Chain, GLYCEROL, ...
Authors:Jette, C.A, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8W
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BU of 7k8w by Molmil
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C119
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C119 Fab Heavy Chain, ...
Authors:Sharaf, N.G, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8T
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BU of 7k8t by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C002 (State 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C002 Fab Heavy Chain, ...
Authors:Malyutin, A.G, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8U
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BU of 7k8u by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C104
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C104 Fab Heavy Chain, ...
Authors:Barnes, C.O, Malyutin, A.G, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K90
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BU of 7k90 by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C144
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C144 Fab Heavy Chain, C144 Fab Light Chain, ...
Authors:Barnes, C.O, Esswein, S.R, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7KL9
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BU of 7kl9 by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the ACE2 protein decoy, CTC-445.2 (State 4)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CTC-445.2 inhibitor, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-10-29
Release date:2020-11-11
Last modified:2020-12-16
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2.
Science, 370, 2020
7LSE
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BU of 7lse by Molmil
Crystal structure of the human neutralizing antibody Fab fragment T025 bound to TBEV EDIII (Far Eastern Subtype)
Descriptor: Envelope protein E, GLYCEROL, T025 Fab Heavy Chain, ...
Authors:Keeffe, J.R, Bjorkman, P.J.
Deposit date:2021-02-18
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease.
J.Exp.Med., 218, 2021
7LSF
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BU of 7lsf by Molmil
Crystal structure of the human neutralizing antibody Fab fragment T025 bound to TBEV EDIII (Western Subtype)
Descriptor: Envelope protein E, GLYCEROL, SODIUM ION, ...
Authors:Keeffe, J.R, Bjorkman, P.J.
Deposit date:2021-02-18
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease.
J.Exp.Med., 218, 2021
7LSG
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BU of 7lsg by Molmil
Crystal structure of the human neutralizing antibody Fab fragment T025 bound to TBEV EDIII (Siberian Subtype)
Descriptor: Core protein, T025 Fab Heavy Chain, T025 Fab Light Chain
Authors:Keeffe, J.R, Bjorkman, P.J.
Deposit date:2021-02-18
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease.
J.Exp.Med., 218, 2021
7LO6
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BU of 7lo6 by Molmil
Structure of CD4 mimetic BNM-III-170 in complex with BG505 SOSIP.664 HIV-1 Env trimer and 17b Fab
Descriptor: 17b Fab Heavy Chain, 17b Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Jette, C.A, Bjorkman, P.J.
Deposit date:2021-02-09
Release date:2021-04-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation.
Nat Commun, 12, 2021
7LOK
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BU of 7lok by Molmil
Structure of CD4 mimetic M48U1 in complex with BG505 SOSIP.664 HIV-1 Env trimer and 17b Fab
Descriptor: 17b Fab Heavy Chain, 17b Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Jette, C.A, Bjorkman, P.J.
Deposit date:2021-02-10
Release date:2021-04-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation.
Nat Commun, 12, 2021
7M6F
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BU of 7m6f by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, BG1-22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG1-22 Fab Heavy Chain, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2021-03-25
Release date:2021-05-05
Last modified:2021-06-23
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV.
Cell, 184, 2021
7M6E
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BU of 7m6e by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, BG10-19
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BG10-19 Fab Heavy Chain, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2021-03-25
Release date:2021-05-05
Last modified:2021-06-23
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV.
Cell, 184, 2021
7M6H
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BU of 7m6h by Molmil
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, BG7-20
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BG7-20 Fab Heavy Chain, BG7-20 Fab Light Chain, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2021-03-25
Release date:2021-05-05
Last modified:2021-06-23
Method:ELECTRON MICROSCOPY (4 Å)
Cite:B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV.
Cell, 184, 2021
7M6G
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BU of 7m6g by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, BG7-15
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG7-15 Fab Heavy Chain, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2021-03-25
Release date:2021-05-05
Last modified:2021-06-23
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV.
Cell, 184, 2021
7M6D
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BU of 7m6d by Molmil
Structure of the SARS-CoV-2 RBD in complex with neutralizing antibodies BG4-25 and CR3022
Descriptor: BG4-25 Fab Heavy Chain, BG4-25 Fab Light Chain, CR3022 Fab Heavy Chain, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2021-03-25
Release date:2021-05-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV.
Cell, 184, 2021
7M6I
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BU of 7m6i by Molmil
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, BG1-24
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG1-24 Fab Heavy Chain, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2021-03-25
Release date:2021-05-05
Last modified:2021-06-23
Method:ELECTRON MICROSCOPY (4 Å)
Cite:B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV.
Cell, 184, 2021
7MXE
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BU of 7mxe by Molmil
Ab1245 Fab in complex with BG505 SOSIP.664 and 8ANC195 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 G52K5 Fab heavy chain, ...
Authors:Abernathy, M.E, Bjorkman, P.J.
Deposit date:2021-05-19
Release date:2021-10-27
Last modified:2021-11-03
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope.
Npj Vaccines, 6, 2021

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