7M6E

Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, BG10-19

Summary for 7M6E

• Entry DOI: 10.2210/pdb7m6e/pdb
• EMDB information: 23693
• Descriptor: Spike glycoprotein, BG10-19 Fab Heavy Chain, BG10-19 Fab Light Chain, ... (5 entities in total)
• Functional Keywords: sars-cov-2, coronavirus, covid-19, antibody, neutralizing antibody, receptor binding domain, spike glycoprotein, antiviral protein, viral protein-antiviral protein complex, viral protein/antiviral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 9
• Total formula weight: 578455.10

Authors

Barnes, C.O.,Bjorkman, P.J. (deposition date: 2021-03-25, release date: 2021-05-05, Last modification date: 2021-06-23)

• Primary citation: Scheid, J.F.,Barnes, C.O.,Eraslan, B.,Hudak, A.,Keeffe, J.R.,Cosimi, L.A.,Brown, E.M.,Muecksch, F.,Weisblum, Y.,Zhang, S.,Delorey, T.,Woolley, A.E.,Ghantous, F.,Park, S.M.,Phillips, D.,Tusi, B.,Huey-Tubman, K.E.,Cohen, A.A.,Gnanapragasam, P.N.P.,Rzasa, K.,Hatziioanno, T.,Durney, M.A.,Gu, X.,Tada, T.,Landau, N.R.,West Jr., A.P.,Rozenblatt-Rosen, O.,Seaman, M.S.,Baden, L.R.,Graham, D.B.,Deguine, J.,Bieniasz, P.D.,Regev, A.,Hung, D.,Bjorkman, P.J.,Xavier, R.J.; B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV.; Cell, 184:3205-, 2021; PubMed: 34015271; DOI: 10.1016/j.cell.2021.04.032

Experimental method

ELECTRON MICROSCOPY (3.3 Å)