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PDB: 25 件

3ZPV
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Crystal structure of Drosophila Pygo PHD finger in complex with Legless HD1 domain
分子名称: PROTEIN BCL9 HOMOLOG, PROTEIN PYGOPUS, ZINC ION
著者Miller, T.C.R, Mieszczanek, J, Sanchez-Barrena, M.J, Rutherford, T.J, Fiedler, M, Bienz, M.
登録日2013-03-02
公開日2013-10-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Evolutionary Adaptation of the Fly Pygo Phd Finger Towards Recognizing Histone H3 Tail Methylated at Arginine 2
Structure, 21, 2013
4WIP
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BU of 4wip by Molmil
DIX domain of human Dvl2
分子名称: PENTAETHYLENE GLYCOL, Segment polarity protein dishevelled homolog DVL-2
著者Fiedler, M, Bienz, M, Madrzak, J, Chin, J.W.
登録日2014-09-26
公開日2015-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.691 Å)
主引用文献Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization.
Nat Commun, 6, 2015
7QCE
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BU of 7qce by Molmil
Crystal structure of an atypical PHD finger of VIN3
分子名称: DI(HYDROXYETHYL)ETHER, VIN3 (Protein VERNALIZATION INSENSITIVE 3), ZINC ION
著者Franco-Echevarria, E, Fiedler, M, Dean, C, Bienz, M.
登録日2021-11-23
公開日2022-11-16
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Plant vernalization proteins contain unusual PHD superdomains without histone H3 binding activity.
J.Biol.Chem., 298, 2022
5LNP
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BU of 5lnp by Molmil
Domain-swapped dimer of human Dishevelled2 DEP domain: monoclinic crystal form crystallised from monomeric fraction
分子名称: SULFATE ION, Segment polarity protein dishevelled homolog DVL-2
著者Renko, M, Gammons, M.V, Bienz, M.
登録日2016-08-05
公開日2016-10-12
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled.
Mol.Cell, 64, 2016
7OQV
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BU of 7oqv by Molmil
Crystal structure of the polymerising VEL domain of VIN3 (I575D mutant)
分子名称: Protein VERNALIZATION INSENSITIVE 3
著者Fiedler, M, Franco-Echevarria, E, Dean, C, Bienz, M.
登録日2021-06-04
公開日2022-11-09
最終更新日2022-11-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Cell Rep, 41, 2022
4UP5
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BU of 4up5 by Molmil
Crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a chemical fragment
分子名称: 6-methoxy-1,3-benzothiazol-2-amine, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ...
著者Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M.
登録日2014-06-12
公開日2014-11-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger.
Acs Chem.Biol., 9, 2014
4UP0
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BU of 4up0 by Molmil
Ternary crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a H3K4me2 peptide
分子名称: HISTONE H3.1, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ...
著者Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M.
登録日2014-06-11
公開日2014-11-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger.
Acs Chem.Biol., 9, 2014
7O6U
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BU of 7o6u by Molmil
Crystal structure of the VIN3 VEL polymerising domain (R554A R556D mutant)
分子名称: Protein VERNALIZATION INSENSITIVE 3
著者Fiedler, M, Franco-Echevarria, E, Dean, C, Bienz, M.
登録日2021-04-12
公開日2022-11-09
最終更新日2022-11-23
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Cell Rep, 41, 2022
7O6T
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BU of 7o6t by Molmil
Crystal structure of the polymerising VEL domain of VIN3 (R556D I575D mutant)
分子名称: MAGNESIUM ION, Protein VERNALIZATION INSENSITIVE 3
著者Fiedler, M, Franco-Echevarria, E, Dean, C, Bienz, M.
登録日2021-04-12
公開日2022-11-09
最終更新日2022-11-23
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Cell Rep, 41, 2022
7O6W
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BU of 7o6w by Molmil
Crystal structure of (the) VEL1 VEL polymerising domain (I664D mutant)
分子名称: PHOSPHATE ION, VIN3-like protein 2
著者Fiedler, M, Franco-Echevarria, E, Dean, C, Bienz, M.
登録日2021-04-12
公開日2022-11-09
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Cell Rep, 41, 2022
7O6V
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BU of 7o6v by Molmil
Crystal structure of the VEL1 VEL polymerising domain (R643A K645D I664D mutant)
分子名称: VIN3-like protein 2
著者Fiedler, M, Franco-Echevarria, E, Dean, C, Bienz, M.
登録日2021-04-12
公開日2022-11-09
最終更新日2022-11-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control.
Cell Rep, 41, 2022
5SUY
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BU of 5suy by Molmil
Domain-swapped dimer of human Dishevelled2 DEP domain: monoclinic crystal form crystallised from dimeric fraction
分子名称: SULFATE ION, Segment polarity protein dishevelled homolog DVL-2
著者Renko, M, Gammons, M.V, Bienz, M.
登録日2016-08-04
公開日2016-10-12
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled.
Mol.Cell, 64, 2016
5SUZ
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BU of 5suz by Molmil
Domain-swapped dimer of human Dishevelled2 DEP domain: C-centered monoclinic crystal form crystallised from monomeric fraction
分子名称: Segment polarity protein dishevelled homolog DVL-2
著者Renko, M, Gammons, M.V, Bienz, M.
登録日2016-08-04
公開日2016-10-12
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled.
Mol.Cell, 64, 2016
3SL9
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BU of 3sl9 by Molmil
X-ray structure of Beta catenin in complex with Bcl9
分子名称: 1,2-ETHANEDIOL, B-cell CLL/lymphoma 9 protein, Catenin beta-1, ...
著者Gupta, D, Bienz, M.
登録日2011-06-24
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid.
Nat Commun, 3, 2012
3SLA
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BU of 3sla by Molmil
X-ray structure of first four repeats of human beta-catenin
分子名称: Catenin beta-1, GLYCEROL, SODIUM ION
著者Gupta, D, Bienz, M.
登録日2011-06-24
公開日2012-02-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid.
Nat Commun, 3, 2012
6RSN
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BU of 6rsn by Molmil
SOSEKI polymerising domain (SOK4 D85A mutant)
分子名称: SULFATE ION, UPSTREAM OF FLC-like protein (DUF966)
著者Fiedler, M, Bienz, M.
登録日2019-05-21
公開日2020-01-29
最終更新日2020-02-19
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献DIX Domain Polymerization Drives Assembly of Plant Cell Polarity Complexes.
Cell, 180, 2020
6S9R
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BU of 6s9r by Molmil
Crystal structure of SSDP from D. melanogaster
分子名称: Sequence-specific single-stranded DNA-binding protein, isoform A
著者Renko, M, Bienz, M.
登録日2019-07-15
公開日2019-10-09
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Proc.Natl.Acad.Sci.USA, 116, 2019
6S9T
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BU of 6s9t by Molmil
Dimerization domain of Xenopus laevis LDB1 in complex with darpin 3
分子名称: Darpin 3, LIM domain-binding protein 1, TETRAETHYLENE GLYCOL
著者Renko, M, Schaefer, J.V, Pluckthun, A, Bienz, M.
登録日2019-07-15
公開日2019-10-09
最終更新日2019-10-23
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Proc.Natl.Acad.Sci.USA, 116, 2019
6S9S
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BU of 6s9s by Molmil
Dimerization domain of Xenopus laevis LDB1 in complex with darpin 10
分子名称: Darpin 10, LIM domain-binding protein 1
著者Renko, M, Schaefer, J.V, Pluckthun, A, Bienz, M.
登録日2019-07-15
公開日2019-10-09
最終更新日2019-10-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Proc.Natl.Acad.Sci.USA, 116, 2019
2VPB
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BU of 2vpb by Molmil
Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex
分子名称: B-CELL CLL/LYMPHOMA 9 PROTEIN, PYGOPUS HOMOLOG 1, SODIUM ION, ...
著者Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M.
登録日2008-02-27
公開日2008-06-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
2VPG
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BU of 2vpg by Molmil
Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex
分子名称: B-CELL CLL/LYMPHOMA 9 PROTEIN, GLYCEROL, HISTONE H3 TAIL, ...
著者Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Bienz, M, Evans, P.
登録日2008-02-27
公開日2008-06-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
2VPE
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BU of 2vpe by Molmil
Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex
分子名称: B-CELL CLL/LYMPHOMA 9 PROTEIN, GLYCEROL, HISTONE H3 TAIL, ...
著者Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M.
登録日2008-02-27
公開日2008-06-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
2VP7
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Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex
分子名称: B-CELL CLL/LYMPHOMA 9 PROTEIN, PYGOPUS HOMOLOG 1, SULFATE ION, ...
著者Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M.
登録日2008-02-26
公開日2008-06-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
2VPD
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BU of 2vpd by Molmil
Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex
分子名称: B-CELL CLL/LYMPHOMA 9 PROTEIN, PYGOPUS HOMOLOG 1, ZINC ION
著者Fiedler, M, Sanchez-Barrena, M.J, Nekrasov, M, Mieszczanek, J, Rybin, V, Muller, J, Evans, P, Bienz, M.
登録日2008-02-27
公開日2008-06-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Decoding of Methylated Histone H3 Tail by the Pygo- Bcl9 Wnt Signaling Complex.
Mol.Cell, 30, 2008
2XB1
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BU of 2xb1 by Molmil
Crystal structure of the human Pygo2 PHD finger in complex with the B9L HD1 domain
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, PYGOPUS HOMOLOG 2, ...
著者Miller, T.C, Rutherford, T.J, Johnson, C.M, Fiedler, M, Bienz, M.
登録日2010-04-01
公開日2010-07-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Allosteric Remodeling of the Histone H3 Binding Pocket in the Pygo2 Phd Finger Triggered by its Binding to the B9L/Bcl9 Co-Factor.
J.Mol.Biol., 401, 2010

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