7PDZ
 
 | | Structure of capping protein bound to the barbed end of a cytoplasmic actin filament | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | Authors: | Funk, J, Merino, F, Schacks, M, Rottner, K, Raunser, S, Bieling, P. | | Deposit date: | 2021-08-09 | | Release date: | 2021-09-01 | | Last modified: | 2021-10-06 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | A barbed end interference mechanism reveals how capping protein promotes nucleation in branched actin networks.
Nat Commun, 12, 2021
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6FHL
 | | Cryo-EM structure of F-actin in complex with ADP-Pi | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Merino, F, Pospich, S, Funk, J, Wagner, T, Kuellmer, F, Arndt, H.-D, Bieling, P, Raunser, S. | | Deposit date: | 2018-01-15 | | Release date: | 2018-06-13 | | Last modified: | 2018-08-29 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
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7ZBQ
 | | Structure of the ADP-ribosyltransferase TccC3HVR from Photorhabdus Luminescens | | Descriptor: | TccC3 | | Authors: | Lindemann, F, Belyy, A, Friedrich, D, Schmieder, P, Bardiaux, B, Roderer, D, Funk, J, Protze, J, Bieling, P, Oschkinat, H, Raunser, S. | | Deposit date: | 2022-03-24 | | Release date: | 2022-06-29 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin.
Nat Commun, 13, 2022
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8OI6
 | | Cryo-EM structure of the undecorated barbed end of filamentous beta/gamma actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | Authors: | Oosterheert, W, Blanc, F.E.C, Roy, A, Belyy, A, Hofnagel, O, Hummer, G, Bieling, P, Raunser, S. | | Deposit date: | 2023-03-22 | | Release date: | 2023-08-09 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (3.59 Å) | | Cite: | Molecular mechanisms of inorganic-phosphate release from the core and barbed end of actin filaments.
Nat.Struct.Mol.Biol., 30, 2023
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8OI8
 | | Cryo-EM structure of ADP-bound, filamentous beta-actin harboring the R183W mutation | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | Authors: | Oosterheert, W, Blanc, F.E.C, Roy, A, Belyy, A, Hofnagel, O, Hummer, G, Bieling, P, Raunser, S. | | Deposit date: | 2023-03-22 | | Release date: | 2023-08-16 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (2.28 Å) | | Cite: | Molecular mechanisms of inorganic-phosphate release from the core and barbed end of actin filaments.
Nat.Struct.Mol.Biol., 30, 2023
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8OID
 | | Cryo-EM structure of ADP-bound, filamentous beta-actin harboring the N111S mutation | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | Authors: | Oosterheert, W, Blanc, F.E.C, Roy, A, Belyy, A, Hofnagel, O, Hummer, G, Bieling, P, Raunser, S. | | Deposit date: | 2023-03-22 | | Release date: | 2023-08-09 | | Last modified: | 2023-11-22 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Molecular mechanisms of inorganic-phosphate release from the core and barbed end of actin filaments.
Nat.Struct.Mol.Biol., 30, 2023
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9FJY
 | | Structure of the DNase I- and phalloidin-bound pointed end of F-actin (conformer 2). | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | | Authors: | Boiero Sanders, M, Oosterheert, W, Hofnagel, O, Bieling, P, Raunser, S. | | Deposit date: | 2024-05-31 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (3.79 Å) | | Cite: | Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly.
Nat Commun, 15, 2024
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9FJM
 | | Cryo-EM structure of the phalloidin-bound pointed end of the actin filament. | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | Authors: | Boiero Sanders, M, Oosterheert, W, Hofnagel, O, Bieling, P, Raunser, S. | | Deposit date: | 2024-05-31 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (3.65 Å) | | Cite: | Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly.
Nat Commun, 15, 2024
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9FJU
 | | Structure of the DNase I- and phalloidin-bound pointed end of F-actin (conformer 1) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | | Authors: | Boiero Sanders, M, Oosterheert, W, Hofnagel, O, Bieling, P, Raunser, S. | | Deposit date: | 2024-05-31 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (3.84 Å) | | Cite: | Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly.
Nat Commun, 15, 2024
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9FJO
 | | Structure of the undecorated pointed end of F-actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Boiero Sanders, M, Oosterheert, W, Hofnagel, O, Bieling, P, Raunser, S. | | Deposit date: | 2024-05-31 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly.
Nat Commun, 15, 2024
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5OOE
 | | Cryo-EM structure of F-actin in complex with AppNHp (AMPPNP) | | Descriptor: | Actin, alpha skeletal muscle, MAGNESIUM ION, ... | | Authors: | Merino, F, Pospich, S, Funk, J, Kuellmer, F, Arndt, H.-D, Bieling, P, Raunser, S. | | Deposit date: | 2017-08-07 | | Release date: | 2018-06-13 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
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5OOD
 | | Cryo-EM structure of jasplakinolide-stabilized F-actin in complex with ADP-Pi | | Descriptor: | (4~{R},7~{R},10~{S},13~{S},15~{E},19~{S})-10-(4-azanylbutyl)-4-(4-hydroxyphenyl)-7-(1~{H}-indol-3-ylmethyl)-8,13,15,19-tetramethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | | Authors: | Merino, F, Pospich, S, Funk, J, Kuellmer, F, Arndt, H.-D, Bieling, P, Raunser, S. | | Deposit date: | 2017-08-07 | | Release date: | 2018-06-13 | | Last modified: | 2019-12-04 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
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5ONV
 | | Cryo-EM structure of F-actin in complex with ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Merino, F, Pospich, S, Funk, J, Kuellmer, F, Arndt, H.-D, Bieling, P, Raunser, S. | | Deposit date: | 2017-08-04 | | Release date: | 2018-06-13 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
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5OOC
 | | Cryo-EM structure of jasplakinolide-stabilized F-actin in complex with ADP | | Descriptor: | (4~{R},7~{R},10~{S},13~{S},15~{E},19~{S})-10-(4-azanylbutyl)-4-(4-hydroxyphenyl)-7-(1~{H}-indol-3-ylmethyl)-8,13,15,19-tetramethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | | Authors: | Merino, F, Pospich, S, Funk, J, Kuellmer, F, Arndt, H.-D, Bieling, P, Raunser, S. | | Deposit date: | 2017-08-07 | | Release date: | 2018-06-13 | | Last modified: | 2019-10-16 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
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5OOF
 | | Cryo-EM structure of F-actin in complex with ADP-BeFx | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Merino, F, Pospich, S, Funk, J, Kuellmer, F, Arndt, H.-D, Bieling, P, Raunser, S. | | Deposit date: | 2017-08-07 | | Release date: | 2018-06-13 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
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8RV2
 | | Structure of the formin INF2 bound to the barbed end of F-actin. | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. | | Deposit date: | 2024-01-31 | | Release date: | 2024-04-10 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.41 Å) | | Cite: | Molecular mechanism of actin filament elongation by formins.
Science, 384, 2024
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8RTT
 | | Structure of the formin Cdc12 bound to the barbed end of phalloidin-stabilized F-actin. | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | Authors: | Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. | | Deposit date: | 2024-01-29 | | Release date: | 2024-04-10 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.56 Å) | | Cite: | Molecular mechanism of actin filament elongation by formins.
Science, 384, 2024
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8RU2
 | | Structure of the F-actin barbed end bound by formin mDia1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | Authors: | Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. | | Deposit date: | 2024-01-29 | | Release date: | 2024-04-10 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.49 Å) | | Cite: | Molecular mechanism of actin filament elongation by formins.
Science, 384, 2024
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8RTY
 | | Structure of the F-actin barbed end bound by Cdc12 and profilin (ring complex) at a resolution of 6.3 Angstrom | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | Authors: | Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. | | Deposit date: | 2024-01-29 | | Release date: | 2024-04-10 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (6.25 Å) | | Cite: | Molecular mechanism of actin filament elongation by formins.
Science, 384, 2024
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8RU0
 | | Structure of the undecorated barbed end of F-actin. | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | Authors: | Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. | | Deposit date: | 2024-01-29 | | Release date: | 2024-04-10 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.08 Å) | | Cite: | Molecular mechanism of actin filament elongation by formins.
Science, 384, 2024
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