8OI8

Cryo-EM structure of ADP-bound, filamentous beta-actin harboring the R183W mutation

Summary for 8OI8

Entry DOI	10.2210/pdb8oi8/pdb
Related	8OI6
EMDB information	16887 16888
Descriptor	Actin, cytoplasmic 1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	actin filament, cytoskeletal protein, atpase, structural protein
Biological source	Homo sapiens (human)
Total number of polymer chains	5
Total formula weight	211220.70
Authors	Oosterheert, W.,Blanc, F.E.C.,Roy, A.,Belyy, A.,Hofnagel, O.,Hummer, G.,Bieling, P.,Raunser, S. (deposition date: 2023-03-22, release date: 2023-08-16, Last modification date: 2023-11-22)
Primary citation	Oosterheert, W.,Blanc, F.E.C.,Roy, A.,Belyy, A.,Sanders, M.B.,Hofnagel, O.,Hummer, G.,Bieling, P.,Raunser, S. Molecular mechanisms of inorganic-phosphate release from the core and barbed end of actin filaments. Nat.Struct.Mol.Biol., 30:1774-1785, 2023 Cited by PubMed: 37749275 DOI: 10.1038/s41594-023-01101-9 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.28 Å)

Structure validation