8OI8
Cryo-EM structure of ADP-bound, filamentous beta-actin harboring the R183W mutation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (C, A, B, D, E) | Actin, cytoplasmic 1 | polymer | 375 | 41792.6 | 5 | UniProt (P60709) Pfam (PF00022) | Homo sapiens (human) | Beta-actin |
| 2 | F, H, J, L, N (C, A, B, D, E) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 5 | Chemie (ADP) | |||
| 3 | G, I, K, M, O (C, A, B, D, E) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 4 | P, Q, R, S, T (C, A, B, D, E) | water | water | 18.0 | 585 | Chemie (HOH) |
Sequence modifications
C, A, B, D, E: 1 - 375 (UniProt: P60709)
| PDB | External Database | Details |
|---|---|---|
| Trp 183 | Arg 183 | engineered mutation |
| Ala 272 | Cys 272 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 208963.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2257.5 | |
| All* | Total formula weight | 211220.7 |
