5DC2
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![BU of 5dc2 by Molmil](/molmil-images/mine/5dc2) | X-RAY CRYSTAL STRUCTURE OF A ENZYMATICALLY DEGRADED BIAPENEM-ADDUCT OF L,D-TRANSPEPTIDASE 2 FROM MYCOBACTERIUM TUBERCULOSIS | Descriptor: | (4S)-4-methyl-2,5,7-trioxoheptanoic acid, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Pan, Y, Basta, L, Lamichhane, G, Bianchet, M.A. | Deposit date: | 2015-08-23 | Release date: | 2016-10-05 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (2.182 Å) | Cite: | Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem. BMC Biochem., 18, 2017
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1KBO
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![BU of 1kbo by Molmil](/molmil-images/mine/1kbo) | Complex of Human recombinant NAD(P)H:Quinone Oxide reductase type 1 with 5-methoxy-1,2-dimethyl-3-(phenoxymethyl)indole-4,7-dione (ES1340) | Descriptor: | 5-METHOXY-1,2-DIMETHYL-3-(PHENOXYMETHYL)INDOLE-4,7-DIONE, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H dehydrogenase [quinone] 1 | Authors: | Faig, M, Bianchet, M.A, Amzel, L.M. | Deposit date: | 2001-11-06 | Release date: | 2002-01-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Characterization of a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1 by biochemical, X-ray crystallographic, and mass spectrometric approaches. Biochemistry, 40, 2001
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1KBQ
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![BU of 1kbq by Molmil](/molmil-images/mine/1kbq) | Complex of Human NAD(P)H quinone Oxidoreductase with 5-methoxy-1,2-dimethyl-3-(4-nitrophenoxymethyl)indole-4,7-dione (ES936) | Descriptor: | 5-METHOXY-1,2-DIMETHYL-3-(4-NITROPHENOXYMETHYL)INDOLE-4,7-DIONE, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H dehydrogenase [quinone] 1 | Authors: | Faig, M, Bianchet, M.A, Amzel, L.M. | Deposit date: | 2001-11-06 | Release date: | 2002-01-16 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Characterization of a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1 by biochemical, X-ray crystallographic, and mass spectrometric approaches. Biochemistry, 40, 2001
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4TXI
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![BU of 4txi by Molmil](/molmil-images/mine/4txi) | Construct of MICAL-1 containing the monooxygenase and calponin homology domains | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Alqassim, S.S, Amzel, L.M, Bianchet, M.A. | Deposit date: | 2014-07-03 | Release date: | 2016-01-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.309 Å) | Cite: | Modulation of MICAL Monooxygenase Activity by its Calponin Homology Domain: Structural and Mechanistic Insights. Sci Rep, 6, 2016
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4TXK
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![BU of 4txk by Molmil](/molmil-images/mine/4txk) | |
1RYA
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![BU of 1rya by Molmil](/molmil-images/mine/1rya) | Crystal Structure of the E. coli GDP-mannose mannosyl hydrolase in complex with GDP and MG | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GDP-mannose mannosyl hydrolase, ... | Authors: | Gabelli, S.B, Bianchet, M.A, Legler, P.M, Mildvan, A.S, Amzel, L.M. | Deposit date: | 2003-12-20 | Release date: | 2004-06-22 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure and mechanism of GDP-mannose glycosyl hydrolase, a Nudix enzyme that cleaves at carbon instead of phosphorus. Structure, 12, 2004
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1GG5
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![BU of 1gg5 by Molmil](/molmil-images/mine/1gg5) | CRYSTAL STRUCTURE OF A COMPLEX OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE AND A CHEMOTHERAPEUTIC DRUG (E09) AT 2.5 A RESOLUTION | Descriptor: | 3-HYDROXYMETHYL-5-AZIRIDINYL-1METHYL-2-[1H-INDOLE-4,7-DIONE]-PROPANOL, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1 | Authors: | Faig, M, Bianchet, M.A, Winski, S, Hargreaves, R, Moody, C.J, Hudnott, A.R, Ross, D, Amzel, L.M. | Deposit date: | 2000-07-12 | Release date: | 2001-09-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure-based development of anticancer drugs: complexes of NAD(P)H:quinone oxidoreductase 1 with chemotherapeutic quinones. Structure, 9, 2001
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1H69
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![BU of 1h69 by Molmil](/molmil-images/mine/1h69) | CRYSTAL STRUCTURE OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE CO WITH 2,3,5,6,TETRAMETHYL-P-BENZOQUINONE (DUROQUINONE) AT 2.5 ANGSTROM RESOLUTION | Descriptor: | 3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1 | Authors: | Faig, M, Bianchet, M.A, Chen, S, Winski, S, Ross, D, Amzel, L.M. | Deposit date: | 2001-06-08 | Release date: | 2001-09-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structure-Based Development of Anticancer Drugs: Complexes of Nad(P)H:Quinone Oxidoreductase 1 with Chemotherapeutic Quinones Structure, 9, 2001
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1H66
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![BU of 1h66 by Molmil](/molmil-images/mine/1h66) | CRYSTAL STRUCTURE OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE CO WITH 2,5-diaziridinyl-3-hydroxyl-6-methyl-1,4-benzoquinone | Descriptor: | 2,5-DIAZIRIDIN-1-YL-3-(HYDROXYMETHYL)-6-METHYLCYCLOHEXA-2,5-DIENE-1,4-DIONE, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1 | Authors: | Faig, M, Bianchet, M.A, Winski, S, Ross, D, Amzel, L.M. | Deposit date: | 2001-06-06 | Release date: | 2001-09-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-Based Development of Anticancer Drugs: Complexes of Nad(P)H:Quinone Oxidoreductase 1 with Chemotherapeutic Quinones Structure, 9, 2001
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5D7H
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![BU of 5d7h by Molmil](/molmil-images/mine/5d7h) | X-RAY CRYSTAL STRUCTURE OF L,D TRANSPEPTIDASE 2 FROM MYCOBACTERIUM TUBERCULOSIS | Descriptor: | GLYCEROL, L,D-transpeptidase 2, SULFATE ION | Authors: | Saavedra, H, Basta, L.A, Lamichhane, G, Bianchet, M.A. | Deposit date: | 2015-08-13 | Release date: | 2016-09-28 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem. BMC Biochem., 18, 2017
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2GT4
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![BU of 2gt4 by Molmil](/molmil-images/mine/2gt4) | Crystal Structure of the Y103F mutant of the GDP-mannose mannosyl hydrolase in complex with GDP-mannose and MG+2 | Descriptor: | GDP-mannose mannosyl hydrolase, GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, MAGNESIUM ION, ... | Authors: | Gabelli, S.B, Bianchet, M.A, Azurmendi, H.F, Mildvan, A.S, Amzel, L.A. | Deposit date: | 2006-04-27 | Release date: | 2006-12-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | X-ray, NMR, and mutational studies of the catalytic cycle of the GDP-mannose mannosyl hydrolase reaction. Biochemistry, 45, 2006
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2GT2
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![BU of 2gt2 by Molmil](/molmil-images/mine/2gt2) | Structure of the E. coli GDP-mannose mannosyl hydrolase | Descriptor: | GDP-mannose mannosyl hydrolase | Authors: | Gabelli, S.B, Bianchet, M.A, Azurmendi, H.F, MIldvan, A.S, Amzel, L.M. | Deposit date: | 2006-04-27 | Release date: | 2006-12-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray, NMR, and mutational studies of the catalytic cycle of the GDP-mannose mannosyl hydrolase reaction. Biochemistry, 45, 2006
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1A78
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![BU of 1a78 by Molmil](/molmil-images/mine/1a78) | COMPLEX OF TOAD OVARY GALECTIN WITH THIO-DIGALACTOSE | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GALECTIN-1, beta-D-galactopyranose-(1-1)-1-thio-beta-D-galactopyranose | Authors: | Amzel, L.M, Bianchet, M.A, Ahmed, H, Vasta, G.R. | Deposit date: | 1998-03-20 | Release date: | 1998-10-14 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Soluble beta-galactosyl-binding lectin (galectin) from toad ovary: crystallographic studies of two protein-sugar complexes Proteins, 40, 2000
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1KHZ
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![BU of 1khz by Molmil](/molmil-images/mine/1khz) | Structure of the ADPR-ase in complex with AMPCPR and Mg | Descriptor: | ADP-ribose pyrophosphatase, ALPHA-BETA METHYLENE ADP-RIBOSE, CHLORIDE ION, ... | Authors: | Gabelli, S.B, Bianchet, M.A, Bessman, M.J, Amzel, L.M. | Deposit date: | 2001-12-01 | Release date: | 2002-10-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Mechanism of the Escherichia coli ADP-ribose pyrophosphatase, a Nudix hydrolase. Biochemistry, 41, 2002
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1PBO
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![BU of 1pbo by Molmil](/molmil-images/mine/1pbo) | COMPLEX OF BOVINE ODORANT BINDING PROTEIN (OBP) WITH A SELENIUM CONTAINING ODORANT | Descriptor: | 4-butyl-5-propyl-1,3-selenazol-2-amine, ODORANT BINDING PROTEIN | Authors: | Amzel, L.M, Bianchet, M.A, Monaco, H, Bains, G. | Deposit date: | 1996-07-15 | Release date: | 1997-07-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The three-dimensional structure of bovine odorant binding protein and its mechanism of odor recognition. Nat.Struct.Biol., 3, 1996
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1NQY
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![BU of 1nqy by Molmil](/molmil-images/mine/1nqy) | The structure of a CoA pyrophosphatase from D. Radiodurans | Descriptor: | CoA pyrophosphatase (MutT/nudix family protein) | Authors: | Kang, L.W, Gabelli, S.B, Bianchet, M.A, Xu, W.L, Bessman, M.J, Amzel, L.M. | Deposit date: | 2003-01-23 | Release date: | 2003-05-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Structure of a coenzyme A pyrophosphatase from Deinococcus radiodurans: a member of the Nudix family. J.Bacteriol., 185, 2003
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1QR2
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![BU of 1qr2 by Molmil](/molmil-images/mine/1qr2) | HUMAN QUINONE REDUCTASE TYPE 2 | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PROTEIN (QUINONE REDUCTASE TYPE 2), ZINC ION | Authors: | Foster, C, Bianchet, M.A, Talalay, P, Amzel, L.M. | Deposit date: | 1999-04-15 | Release date: | 1999-08-18 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of human quinone reductase type 2, a metalloflavoprotein. Biochemistry, 38, 1999
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1NQZ
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![BU of 1nqz by Molmil](/molmil-images/mine/1nqz) | The structure of a CoA pyrophosphatase from D. Radiodurans complexed with a magnesium ion | Descriptor: | CoA pyrophosphatase (MutT/nudix family protein), MAGNESIUM ION | Authors: | Kang, L.W, Gabelli, S.B, Bianchet, M.A, Xu, W.L, Bessman, M.J, Amzel, L.M. | Deposit date: | 2003-01-23 | Release date: | 2003-05-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of a coenzyme A pyrophosphatase from Deinococcus radiodurans: a member of the Nudix family. J.Bacteriol., 185, 2003
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1QRD
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![BU of 1qrd by Molmil](/molmil-images/mine/1qrd) | QUINONE REDUCTASE/FAD/CIBACRON BLUE/DUROQUINONE COMPLEX | Descriptor: | CIBACRON BLUE, DUROQUINONE, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Li, R, Bianchet, M.A, Talalay, P, Amzel, L.M. | Deposit date: | 1995-07-28 | Release date: | 1996-10-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The three-dimensional structure of NAD(P)H:quinone reductase, a flavoprotein involved in cancer chemoprotection and chemotherapy: mechanism of the two-electron reduction. Proc.Natl.Acad.Sci.USA, 92, 1995
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1GA7
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![BU of 1ga7 by Molmil](/molmil-images/mine/1ga7) | CRYSTAL STRUCTURE OF THE ADP-RIBOSE PYROPHOSPHATASE IN COMPLEX WITH GD+3 | Descriptor: | GADOLINIUM ION, HYPOTHETICAL 23.7 KDA PROTEIN IN ICC-TOLC INTERGENIC REGION | Authors: | Gabelli, S.B, Bianchet, M.A, Bessman, M.J, Amzel, L.M. | Deposit date: | 2000-11-29 | Release date: | 2001-05-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | The structure of ADP-ribose pyrophosphatase reveals the structural basis for the versatility of the Nudix family. Nat.Struct.Biol., 8, 2001
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1MK1
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![BU of 1mk1 by Molmil](/molmil-images/mine/1mk1) | Structure of the MT-ADPRase in complex with ADPR, a Nudix enzyme | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, ADPR pyrophosphatase | Authors: | Kang, L.-W, Gabelli, S.B, Bianchet, M.A, Cunningham, J.E, O'Handley, S.F, Amzel, L.M. | Deposit date: | 2002-08-28 | Release date: | 2003-08-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and mechanism of MT-ADPRase, a Nudix hydrolase from Mycobacterium tuberculosis Structure, 11, 2003
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1MP2
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![BU of 1mp2 by Molmil](/molmil-images/mine/1mp2) | Structure of MT-ADPRase (Apoenzyme), a Nudix hydrolase from Mycobacterium tuberculosis | Descriptor: | ADPR pyrophosphatase | Authors: | Kang, L.-W, Gabelli, S.B, Bianchet, M.A, Cunningham, J.E, O'Handley, S.F, Amzel, L.M. | Deposit date: | 2002-09-11 | Release date: | 2003-08-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and mechanism of MT-ADPRase, a Nudix hydrolase from Mycobacterium tuberculosis Structure, 11, 2003
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1MQE
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![BU of 1mqe by Molmil](/molmil-images/mine/1mqe) | Structure of the MT-ADPRase in complex with gadolidium and ADP-ribose, a Nudix enzyme | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, ADPR pyrophosphatase, GADOLINIUM ION | Authors: | Kang, L.-W, Gabelli, S.B, Bianchet, M.A, Cunningham, J.E, O'Handley, S.F, Amzel, L.M. | Deposit date: | 2002-09-16 | Release date: | 2003-08-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and mechanism of MT-ADPRase, a Nudix hydrolase from Mycobacterium tuberculosis Structure, 11, 2003
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1MR2
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![BU of 1mr2 by Molmil](/molmil-images/mine/1mr2) | Structure of the MT-ADPRase in complex with 1 Mn2+ ion and AMP-CP (a inhibitor), a nudix enzyme | Descriptor: | ADPR pyrophosphatase, MANGANESE (II) ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER | Authors: | Kang, L.-W, Gabelli, S.B, Bianchet, M.A, Cunningham, J.E, O'Handley, S.F, Amzel, L.M. | Deposit date: | 2002-09-17 | Release date: | 2003-08-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and mechanism of MT-ADPRase, a Nudix hydrolase from Mycobacterium tuberculosis Structure, 11, 2003
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1MQW
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![BU of 1mqw by Molmil](/molmil-images/mine/1mqw) | Structure of the MT-ADPRase in complex with three Mn2+ ions and AMPCPR, a Nudix enzyme | Descriptor: | ADPR pyrophosphatase, ALPHA-BETA METHYLENE ADP-RIBOSE, MANGANESE (II) ION | Authors: | Kang, L.-W, Gabelli, S.B, Bianchet, M.A, Cunningham, J.E, O'Handley, S.F, Amzel, L.M. | Deposit date: | 2002-09-17 | Release date: | 2003-08-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and mechanism of MT-ADPRase, a Nudix hydrolase from Mycobacterium tuberculosis Structure, 11, 2003
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