Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1KBO

Complex of Human recombinant NAD(P)H:Quinone Oxide reductase type 1 with 5-methoxy-1,2-dimethyl-3-(phenoxymethyl)indole-4,7-dione (ES1340)

Summary for 1KBO
Entry DOI10.2210/pdb1kbo/pdb
Related1D4A 1GG5 1H66 1H69 1KBQ 1QRD
DescriptorNAD(P)H dehydrogenase [quinone] 1, 5-METHOXY-1,2-DIMETHYL-3-(PHENOXYMETHYL)INDOLE-4,7-DIONE, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
Functional Keywordsflavoenzyme, prodrug-enzyme complex, oxidoreductase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P15559
Total number of polymer chains4
Total formula weight127493.18
Authors
Faig, M.,Bianchet, M.A.,Amzel, L.M. (deposition date: 2001-11-06, release date: 2002-01-16, Last modification date: 2024-02-07)
Primary citationWinski, S.L.,Faig, M.,Bianchet, M.A.,Siegel, D.,Swann, E.,Fung, K.,Duncan, M.W.,Moody, C.J.,Amzel, L.M.,Ross, D.
Characterization of a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1 by biochemical, X-ray crystallographic, and mass spectrometric approaches.
Biochemistry, 40:15135-15142, 2001
Cited by
PubMed: 11735396
DOI: 10.1021/bi011324i
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon