1H69
CRYSTAL STRUCTURE OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE CO WITH 2,3,5,6,TETRAMETHYL-P-BENZOQUINONE (DUROQUINONE) AT 2.5 ANGSTROM RESOLUTION
Summary for 1H69
Entry DOI | 10.2210/pdb1h69/pdb |
Related | 1D4A 1DXO 1H66 1QBG |
Descriptor | NAD(P)H DEHYDROGENASE [QUINONE] 1, FLAVIN-ADENINE DINUCLEOTIDE, 3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE, ... (4 entities in total) |
Functional Keywords | flavoprotein, rossmann fold, oxidoreductase |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm: P15559 |
Total number of polymer chains | 4 |
Total formula weight | 127425.08 |
Authors | Faig, M.,Bianchet, M.A.,Chen, S.,Winski, S.,Ross, D.,Amzel, L.M. (deposition date: 2001-06-08, release date: 2001-09-05, Last modification date: 2023-12-13) |
Primary citation | Faig, M.,Bianchet, M.A.,Winski, S.,Hargreaves, R.,Moody, C.J.,Hudnott, A.R.,Ross, D.,Amzel, L.M. Structure-Based Development of Anticancer Drugs: Complexes of Nad(P)H:Quinone Oxidoreductase 1 with Chemotherapeutic Quinones Structure, 9:659-, 2001 Cited by PubMed: 11587640DOI: 10.1016/S0969-2126(01)00636-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.86 Å) |
Structure validation
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