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1QBG

CRYSTAL STRUCTURE OF HUMAN DT-DIAPHORASE (NAD(P)H OXIDOREDUCTASE)

Summary for 1QBG
Entry DOI10.2210/pdb1qbg/pdb
DescriptorNAD(P)H DEHYDROGENASE [QUINONE] 1, FLAVIN-ADENINE DINUCLEOTIDE (2 entities in total)
Functional Keywordsquinone, fad, oxidoreductase, dt-diaphorase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P15559
Total number of polymer chains4
Total formula weight126019.66
Authors
Skelly, J.V.,Sanderson, M.R.,Suter, D.A.,Baumann, U.,Gregory, D.S.,Bennett, M.,Hobbs, S.M.,Neidle, S. (deposition date: 1999-04-20, release date: 2000-04-24, Last modification date: 2024-02-14)
Primary citationSkelly, J.V.,Sanderson, M.R.,Suter, D.A.,Baumann, U.,Read, M.A.,Gregory, D.S.,Bennett, M.,Hobbs, S.M.,Neidle, S.
Crystal structure of human DT-diaphorase: a model for interaction with the cytotoxic prodrug 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954).
J.Med.Chem., 42:4325-4330, 1999
Cited by
PubMed: 10543876
DOI: 10.1021/jm991060m
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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