3R0X
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![BU of 3r0x by Molmil](/molmil-images/mine/3r0x) | Crystal structure of Selenomethionine incorporated apo D-serine deaminase from Salmonella tyhimurium | Descriptor: | 1,2-ETHANEDIOL, D-serine dehydratase, SODIUM ION, ... | Authors: | Bharath, S.R, Shveta, B, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2011-03-09 | Release date: | 2011-06-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Crystal structures of open and closed forms of D-serine deaminase from Salmonella typhimurium - implications on substrate specificity and catalysis Febs J., 2011
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3R0Z
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![BU of 3r0z by Molmil](/molmil-images/mine/3r0z) | Crystal structure of apo D-serine deaminase from Salmonella typhimurium | Descriptor: | 1,2-ETHANEDIOL, D-serine dehydratase, SULFATE ION | Authors: | Bharath, S.R, Shveta, B, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2011-03-09 | Release date: | 2011-06-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of open and closed forms of D-serine deaminase from Salmonella typhimurium - implications on substrate specificity and catalysis Febs J., 2011
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5H3U
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![BU of 5h3u by Molmil](/molmil-images/mine/5h3u) | Sm RNA bound to GEMIN5-WD | Descriptor: | GLYCEROL, Gem-associated protein 5, RNA (5'-R(*AP*AP*UP*UP*UP*UP*UP*GP*AP*C)-3') | Authors: | Bharath, S.R, Tang, X, Song, H. | Deposit date: | 2016-10-27 | Release date: | 2016-12-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.499 Å) | Cite: | Structural basis for specific recognition of pre-snRNA by Gemin5 Cell Res., 26, 2016
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5H3T
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![BU of 5h3t by Molmil](/molmil-images/mine/5h3t) | m7G cap bound to GEMIN5-WD | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, GLYCEROL, Gem-associated protein 5 | Authors: | Bharath, S.R, Tang, X, Song, H. | Deposit date: | 2016-10-27 | Release date: | 2016-12-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.571 Å) | Cite: | Structural basis for specific recognition of pre-snRNA by Gemin5 Cell Res., 26, 2016
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5H3S
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![BU of 5h3s by Molmil](/molmil-images/mine/5h3s) | apo form of GEMIN5-WD | Descriptor: | GLYCEROL, Gem-associated protein 5 | Authors: | Bharath, S.R, Tang, X, Song, H. | Deposit date: | 2016-10-27 | Release date: | 2016-12-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for specific recognition of pre-snRNA by Gemin5 Cell Res., 26, 2016
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4D92
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![BU of 4d92 by Molmil](/molmil-images/mine/4d92) | Salmonella typhimurium D-Cysteine desulfhydrase soaked with beta-chloro-D-alanine shows pyruvate bound 4 A away from active site | Descriptor: | BENZAMIDINE, D-cysteine desulfhydrase, PYRUVIC ACID, ... | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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4D99
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![BU of 4d99 by Molmil](/molmil-images/mine/4d99) | Salmonella typhimurium D-Cysteine desulfhydrase with L-ser bound non-covalently at the active site | Descriptor: | BENZAMIDINE, D-cysteine desulfhydrase, SERINE, ... | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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4D9E
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![BU of 4d9e by Molmil](/molmil-images/mine/4d9e) | D-Cysteine desulfhydrase from Salmonella typhimurium complexed with L-cycloserine (LCS) | Descriptor: | BENZAMIDINE, D-Cysteine desulfhydrase, [5-hydroxy-6-methyl-4-({[(4E)-3-oxo-1,2-oxazolidin-4-ylidene]amino}methyl)pyridin-3-yl]methyl dihydrogen phosphate | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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4D96
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![BU of 4d96 by Molmil](/molmil-images/mine/4d96) | D-Cysteine desulfhydrase from Salmonella typhimurium complexed with 1-amino-1-carboxycyclopropane (ACC) | Descriptor: | BENZAMIDINE, D-cysteine desulfhydrase, N-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-Y-LMETHYL]-1-AMINO-CYCLOPROPANECARBOXYLIC ACID, ... | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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4D9B
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![BU of 4d9b by Molmil](/molmil-images/mine/4d9b) | Pyridoxamine 5' phosphate (PMP) bound form of Salmonella typhimurium D-Cysteine desulfhydrase obtained after co-crystallization with D-cycloserine | Descriptor: | 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, BENZAMIDINE, ... | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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4D9C
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![BU of 4d9c by Molmil](/molmil-images/mine/4d9c) | PMP bound form of Salmonella typhimurium D-Cysteine desulfhydrase obtained after co-crystallization with L-cycloserine | Descriptor: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, BENZAMIDINE, D-Cysteine desulfhydrase | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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4D8T
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![BU of 4d8t by Molmil](/molmil-images/mine/4d8t) | Crystal structure of D-Cysteine desulfhydrase from Salmonella typhimurium at 2.2 A resolution | Descriptor: | BENZAMIDINE, CHLORIDE ION, D-cysteine desulfhydrase, ... | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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4D9F
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![BU of 4d9f by Molmil](/molmil-images/mine/4d9f) | D-Cysteine desulfhydrase from Salmonella typhimurium complexed with D-cycloserine (DCS) | Descriptor: | BENZAMIDINE, D-Cysteine desulfhydrase, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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4D8U
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![BU of 4d8u by Molmil](/molmil-images/mine/4d8u) | Crystal structure of D-Cysteine desulfhydrase from Salmonella typhimurium at 3.3 A in monoclinic space group with 8 subunits in the asymmetric unit | Descriptor: | D-cysteine desulfhydrase, PHOSPHATE ION | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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4D97
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![BU of 4d97 by Molmil](/molmil-images/mine/4d97) | Salmonella typhimurium D-Cysteine desulfhydrase with D-ser bound at active site | Descriptor: | BENZAMIDINE, D-SERINE, D-cysteine desulfhydrase | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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4D8W
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![BU of 4d8w by Molmil](/molmil-images/mine/4d8w) | Salmonella typhimurium D-Cysteine desulfhydrase soaked with D-cys shows pyruvate bound 4 A away from active site | Descriptor: | 1,2-ETHANEDIOL, BENZAMIDINE, CHLORIDE ION, ... | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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8SEI
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![BU of 8sei by Molmil](/molmil-images/mine/8sei) | SF Tau from Down Syndrome | Descriptor: | Microtubule-associated protein tau | Authors: | Hoq, M.R, Bharath, S.R, Jiang, W, Vago, F.S, Bharath, S.R. | Deposit date: | 2023-04-10 | Release date: | 2024-04-03 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo-EM structures of amyloid-beta and tau filaments in Down syndrome. Nat.Struct.Mol.Biol., 31, 2024
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5XX1
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![BU of 5xx1 by Molmil](/molmil-images/mine/5xx1) | Crystal structure of Arginine decarboxylase (AdiA) from Salmonella typhimurium | Descriptor: | Arginine decarboxylase, PHOSPHATE ION | Authors: | Deka, G, Bharath, S.R, Shavithri, H.S, Murthy, M.R.N. | Deposit date: | 2017-06-30 | Release date: | 2018-05-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural studies on the decameric S. typhimurium arginine decarboxylase (ADC): Pyridoxal 5'-phosphate binding induces conformational changes Biochem. Biophys. Res. Commun., 490, 2017
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8F9K
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![BU of 8f9k by Molmil](/molmil-images/mine/8f9k) | |
5JXE
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![BU of 5jxe by Molmil](/molmil-images/mine/5jxe) | Human PD-1 ectodomain complexed with Pembrolizumab Fab | Descriptor: | Pembrolizumab Fab heavy chain, Pembrolizumab Fab light chain, Programmed cell death protein 1 | Authors: | Na, Z, Bharath, S.R, Song, H. | Deposit date: | 2016-05-13 | Release date: | 2016-08-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis for blocking PD-1-mediated immune suppression by therapeutic antibody pembrolizumab. Cell Res., 27, 2017
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3USU
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![BU of 3usu by Molmil](/molmil-images/mine/3usu) | Crystal structure of Butea monosperma seed lectin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Abhilash, J, Geethanandan, K, Bharath, S.R, Sadasivan, C, Haridas, M. | Deposit date: | 2011-11-24 | Release date: | 2012-01-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Crystal structure of Butea monosperma seed lectin To be Published
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3IPV
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![BU of 3ipv by Molmil](/molmil-images/mine/3ipv) | Crystal structure of Spatholobus parviflorus seed lectin | Descriptor: | CALCIUM ION, Lectin alpha chain, Lectin beta chain, ... | Authors: | Geethanandan, K, Bharath, S.R, Abhilash, J, Sadasivan, C, Haridas, M. | Deposit date: | 2009-08-18 | Release date: | 2009-09-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | X-ray structure of a galactose-specific lectin from Spatholobous parviflorous Int.J.Biol.Macromol., 49, 2011
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6AA9
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![BU of 6aa9 by Molmil](/molmil-images/mine/6aa9) | T166A mutant of D-Serine deaminase from Salmonella typhimurium | Descriptor: | D-serine dehydratase, PHOSPHATE ION, SODIUM ION | Authors: | Deka, G, Bharath, S.R, Shavithri, H.S, Murthy, M.R.N. | Deposit date: | 2018-07-17 | Release date: | 2019-07-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural studies on the decameric S. typhimurium arginine decarboxylase (ADC): Pyridoxal 5'-phosphate binding induces conformational changes Biochem. Biophys. Res. Commun., 490, 2017
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5ZMC
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![BU of 5zmc by Molmil](/molmil-images/mine/5zmc) | Structural Basis for Reactivation of -146C>T Mutant TERT Promoter by cooperative binding of p52 and ETS1/2 | Descriptor: | DNA (5'-D(P*CP*GP*GP*GP*GP*AP*CP*CP*CP*GP*GP*AP*AP*GP*GP*G)-3'), DNA (5'-D(P*GP*CP*CP*CP*TP*TP*CP*CP*GP*GP*GP*TP*CP*CP*CP*C)-3'), Nuclear factor NF-kappa-B p100 subunit, ... | Authors: | Xu, X, Bharath, S.R, Song, H. | Deposit date: | 2018-04-02 | Release date: | 2018-09-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Structural basis for reactivating the mutant TERT promoter by cooperative binding of p52 and ETS1. Nat Commun, 9, 2018
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7X0F
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![BU of 7x0f by Molmil](/molmil-images/mine/7x0f) | |