8F9K

TMEM106B doublet filaments extracted from MSTD neurodegenerative human brain

Summary for 8F9K

• Entry DOI: 10.2210/pdb8f9k/pdb
• EMDB information: 28943
• Descriptor: Transmembrane protein 106B, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• Functional Keywords: tmem106b, tmem filament, mstd, neuropeptide
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 6
• Total formula weight: 192246.90

Authors

Hoq, M.R.,Bharath, S.R.,Jiang, W. (deposition date: 2022-11-23, release date: 2023-11-22, Last modification date: 2024-11-06)

• Primary citation: Hoq, M.R.,Bharath, S.R.,Hallinan, G.I.,Fernandez, A.,Vago, F.S.,Ozcan, K.A.,Li, D.,Garringer, H.J.,Vidal, R.,Ghetti, B.,Jiang, W.; Cross-beta helical filaments of Tau and TMEM106B in gray and white matter of multiple system tauopathy with presenile dementia.; Acta Neuropathol, 145:707-710, 2023; PubMed: 36952000; DOI: 10.1007/s00401-023-02563-3

Experimental method

ELECTRON MICROSCOPY (3.4 Å)