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PDB: 50 件

3BZF
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The human non-classical major histocompatibility complex molecule HLA-E
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ...
著者Hoare, H.L, Sullivan, L.C, Ely, L.K, Beddoe, T, Henderson, K.N, Lin, J, Clements, C.S, Reid, H.H, Brooks, A.G, Rossjohn, J.
登録日2008-01-17
公開日2008-04-29
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Subtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class I molecule HLA-E by the CD94-NKG2 natural killer cell receptors
J.Mol.Biol., 377, 2008
4XXF
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L-fuculose 1-phosphate aldolase from Glaciozyma antarctica PI12
分子名称: Fuculose-1-phosphate aldolase, ZINC ION
著者Jaafar, N.R, Abu Bakar, F.D, Abdul Murad, A.M, Illias, R, Littler, D, Beddoe, T, Rossjohn, J, Mahadi, M.N.
登録日2015-01-30
公開日2015-02-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Crystal structure of fuculose aldolase from the Antarctic psychrophilic yeast Glaciozyma antarctica PI12.
Acta Crystallogr.,Sect.F, 72, 2016
4BWG
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Structural basis of subtilase cytotoxin SubAB assembly
分子名称: GLYCEROL, SUBA, SUBTILASE CYTOTOXIN, ...
著者Le Nours, J, Paton, A.W, Byres, E, Troy, S, Herdman, B.P, Johnson, M.D, Paton, J.C, Rossjohn, J, Beddoe, T.
登録日2013-07-02
公開日2013-08-14
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis of Subtilase Cytotoxin Subab Assembly.
J.Biol.Chem., 288, 2013
2WZM
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Crystal structure of a mycobacterium aldo-keto reductase in its apo and liganded form
分子名称: ALDO-KETO REDUCTASE, [(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE
著者Scoble, J, McAlister, A.D, Fulton, Z, Troy, S, Byres, E, Vivian, J.P, Brammananth, R, Wilce, M.C.J, Le Nours, J, Zaker-Tabrizi, L, Coppel, R.L, Crellin, P.K, Rossjohn, J, Beddoe, T.
登録日2009-11-30
公開日2010-02-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Crystal Structure and Comparative Functional Analyses of a Mycobacterium Aldo-Keto Reductase.
J.Mol.Biol., 398, 2010
1MOV
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BU of 1mov by Molmil
Crystal structure of Coral protein mutant
分子名称: GFP-like non-fluorescent chromoprotein, IODIDE ION
著者Prescott, M, Ling, M, Beddoe, T, Oakley, A.J, Dove, S, Hoegh-Guldberg, O, Devenish, R.J, Rossjohn, J.
登録日2002-09-10
公開日2003-04-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The 2.2 a crystal structure of a pocilloporin pigment reveals a nonplanar chromophore conformation.
Structure, 11, 2003
1MOU
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BU of 1mou by Molmil
Crystal structure of Coral pigment
分子名称: GFP-like non-fluorescent chromoprotein, IODIDE ION
著者Prescott, M, Ling, M, Beddoe, T, Oakley, A.J, Dove, S, Hoegh-Guldberg, O, Devenish, R.J, Rossjohn, J.
登録日2002-09-10
公開日2003-04-08
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The 2.2 a crystal structure of a pocilloporin pigment reveals a nonplanar chromophore conformation.
Structure, 11, 2003
1PY9
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The crystal structure of an autoantigen in multiple sclerosis
分子名称: Myelin-oligodendrocyte glycoprotein, SULFATE ION
著者Clements, C.S, Reid, H.H, Beddoe, T, Tynan, F.E, Perugini, M.A, Johns, T.G, Bernard, C.C, Rossjohn, J.
登録日2003-07-08
公開日2003-09-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis
Proc.Natl.Acad.Sci.USA, 100, 2003
4ZY7
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BU of 4zy7 by Molmil
Crystal structure of a Mycobacterial protein
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Uncharacterized protein MSMEG_5817
著者Shahine, A, Rossjohn, J, Beddoe, T.
登録日2015-05-21
公開日2016-05-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of a Mycobacterial protein
To Be Published
4Z9C
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BU of 4z9c by Molmil
EcPltAB Oxidized
分子名称: PHOSPHATE ION, Pertussis toxin-like subunit ArtA, Subtilase cytotoxin subunit B-like protein
著者Littler, D.R, Johnson, M.D, Summers, R.J, Schembri, M.A, Rossjohn, J, Beddoe, T.
登録日2015-04-10
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure and function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G proteins.
J. Biol. Chem., 2017
4Z9D
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EcPltA
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Pertussis toxin-like subunit ArtA, SODIUM ION
著者Littler, D.R, Johnson, M.D, Summers, R.J, Schembri, M.A, Rossjohn, J, Beddoe, T.
登録日2015-04-10
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G proteins.
J. Biol. Chem., 2017
2IY9
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Crystal structure of the A-subunit of the AB5 toxin from E. coli
分子名称: SUBA
著者Paton, A.W, Beddoe, T, Thorpe, C.M, Whisstock, J.C, Wilce, M.C.J, Rossjohn, J, Talbot, U.M, Paton, J.C.
登録日2006-07-13
公開日2006-10-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Ab5 Subtilase Cytotoxin Inactivates the Endoplasmic Reticulum Chaperone Bip
Nature, 443, 2006
1ZHL
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BU of 1zhl by Molmil
Crystal structure of HLA-B*3508 presenting 13-mer EBV antigen LPEPLPQGQLTAY
分子名称: Beta-2-microglobulin, EBV-peptide LPEPLPQGQLTAY, HLA class I histocompatibility antigen, ...
著者Tynan, F.E, Borg, N.A, Miles, J.J, Beddoe, T, El-Hassen, D, Silins, S.L, van Zuylen, W.J, Purcell, A.W, Kjer-Nielsen, L, McCluskey, J, Burrows, S.R, Rossjohn, J.
登録日2005-04-26
公開日2005-05-17
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The high resolution structures of highly bulged viral epitopes bound to the major histocompatability class I: Implications for T-cell receptor engagement and T-cell immunodominance
J.Biol.Chem., 280, 2005
7SKI
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BU of 7ski by Molmil
Pertussis toxin in complex with PJ34
分子名称: N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE, Pertussis toxin subunit 1
著者Littler, D.R, Beddoe, T, Pulliainen, A, Rossjohn, J.
登録日2021-10-20
公開日2022-04-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.09912443 Å)
主引用文献Crystal structures of pertussis toxin with NAD + and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity.
J.Biol.Chem., 298, 2022
7SKK
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pertussis toxin in complex with ADPR and Nicotinamide
分子名称: NICOTINAMIDE, Pertussis toxin subunit 1, SULFATE ION, ...
著者Littler, D.R, Beddoe, T, Pulliainen, A, Rossjohn, J.
登録日2021-10-21
公開日2022-04-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65000772 Å)
主引用文献Crystal structures of pertussis toxin with NAD + and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity.
J.Biol.Chem., 298, 2022
7SNE
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BU of 7sne by Molmil
Pertussis toxin S1 subunit bound to BaAD
分子名称: Pertussis toxin subunit 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5S)-5-(3-carbamoylanilino)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen diphosphate (non-preferred name)
著者Littler, D.R, Beddoe, T.
登録日2021-10-28
公開日2022-04-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.00011 Å)
主引用文献Crystal structures of pertussis toxin with NAD + and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity.
J.Biol.Chem., 298, 2022
7SKY
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BU of 7sky by Molmil
Pertussis toxin S1 bound to NAD+
分子名称: IODIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Pertussis toxin subunit 1
著者Littler, D.R, Beddoe, T, Pulliainen, A, Rossjohn, J.
登録日2021-10-21
公開日2022-04-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.37000132 Å)
主引用文献Crystal structures of pertussis toxin with NAD + and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity.
J.Biol.Chem., 298, 2022
7U6Z
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BU of 7u6z by Molmil
Pertussis toxin E129D NAD
分子名称: IODIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Pertussis toxin subunit 1
著者Littler, D.R, Beddoe, T, Pulliainen, A, Rossjohn, J.
登録日2022-03-06
公開日2022-04-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.30002 Å)
主引用文献Crystal structures of pertussis toxin with NAD + and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity.
J.Biol.Chem., 298, 2022
2AK4
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BU of 2ak4 by Molmil
Crystal Structure of SB27 TCR in complex with HLA-B*3508-13mer peptide
分子名称: Beta-2-microglobulin, EBV peptide LPEPLPQGQLTAY, HLA-B35 variant, ...
著者Tynan, F.E, Burrows, S.R, Buckle, A.M, Clements, C.S, Borg, N.A, Miles, J.J, Beddoe, T, Whisstock, J.C, Wilce, M.C, Silins, S.L, Burrows, J.M, Kjer-Nielsen, L, Konstenko, L, Purcell, A.W, McCluskey, J, Rossjohn, J.
登録日2005-08-03
公開日2005-10-11
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide
Nat.Immunol., 6, 2005
2ARL
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BU of 2arl by Molmil
The 2.0 angstroms crystal structure of a pocilloporin at pH 3.5: the structural basis for the linkage between color transition and halide binding
分子名称: ACETIC ACID, CHLORIDE ION, GFP-like non-fluorescent chromoprotein, ...
著者Wilmann, P.G, Battad, J, Beddoe, T, Olsen, S, Smith, S.C, Dove, S, Devenish, R.J, Rossjohn, J, Prescott, M.
登録日2005-08-19
公開日2006-09-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The 2.0 angstroms crystal structure of a pocilloporin at pH 3.5: the structural basis for the linkage between color transition and halide binding
Photochem.Photobiol., 82, 2006
1ZHK
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BU of 1zhk by Molmil
Crystal structure of HLA-B*3501 presenting 13-mer EBV antigen LPEPLPQGQLTAY
分子名称: Beta-2-microglobulin, EBV-peptide LPEPLPQGQLTAY, HLA class I histocompatibility antigen, ...
著者Tynan, F.E, Borg, N.A, Miles, J.J, Beddoe, T, El-Hassen, D, Silins, S.L, van Zuylen, W.J, Purcell, A.W, Kjer-Nielsen, L, McCluskey, J, Burrows, S.R, Rossjohn, J.
登録日2005-04-26
公開日2005-05-17
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The high resolution structures of highly bulged viral epitopes bound to the major histocompatability class I: Implications for T-cell receptor engagement and T-cell immunodominance
J.Biol.Chem., 280, 2005
1SYV
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BU of 1syv by Molmil
HLA-B*4405 complexed to the dominant self ligand EEFGRAYGF
分子名称: Beta-2-microglobulin, MHC class I antigen, major histocompatibility complex, ...
著者Zernich, D, Purcell, A.W, Macdonald, W.A, Kjer-Nielsen, L, Ely, L.K, Laham, N, Crockford, T, Mifsud, N.A, Tait, B.D, Holdsworth, R, Brooks, A.G, Bottomley, S.P, Beddoe, T, Peh, C.A, Rossjohn, J, McCluskey, J.
登録日2004-04-02
公開日2004-10-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion
J.Exp.Med., 200, 2004
1SYS
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BU of 1sys by Molmil
Crystal structure of HLA, B*4403, and peptide EEPTVIKKY
分子名称: Beta-2-microglobulin, Sorting nexin 5, leukocyte antigen (HLA) class I molecule
著者Zernich, D, Purcell, A.W, Macdonald, W.A, Kjer-Nielsen, L, Ely, L.K, Laham, N, Crockford, T, Mifsud, N.A, Tait, B.D, Holdsworth, R, Brooks, A.G, Bottomley, S.P, Beddoe, T, Peh, C.A, Rossjohn, J, McCluskey, J.
登録日2004-04-01
公開日2004-10-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion
J.Exp.Med., 200, 2004
4L63
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BU of 4l63 by Molmil
Apo form of AB5 holotoxin
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ECXA, ECXB, ...
著者Littler, D.R, Ng, N.M, Rossjohn, J, Beddoe, T.
登録日2013-06-11
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献EcxAB Is a Founding Member of a New Family of Metalloprotease AB5 Toxins with a Hybrid Cholera-like B Subunit.
Structure, 21, 2013
4L6T
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BU of 4l6t by Molmil
GM1 bound form of the ECX AB5 holotoxin
分子名称: ECXA, ECXB, ZINC ION, ...
著者Littler, D.R, Ng, N.M, Rossjohn, J, Beddoe, T.
登録日2013-06-12
公開日2013-11-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.859 Å)
主引用文献EcxAB Is a Founding Member of a New Family of Metalloprotease AB5 Toxins with a Hybrid Cholera-like B Subunit.
Structure, 21, 2013
4L4T
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Structure of human MAIT TCR in complex with human MR1-6-FP
分子名称: 2-amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde, Beta-2-microglobulin, MAIT T-cell receptor alpha chain, ...
著者Patel, O, Kjer-Nielsen, L, Le Nours, J, Eckle, S.B.G, Birkinshaw, R.W, Beddoe, T, Corbett, A.J, Liu, L, Miles, J.J, Meehan, B, Reantragoon, R, Sandoval-Romero, M.L, Sullivan, L.C, Brooks, A.G, Chen, Z, Fairlie, D.P, McCluskey, J, Rossjohn, J.
登録日2013-06-09
公開日2013-07-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Recognition of vitamin B metabolites by mucosal-associated invariant T cells.
Nat Commun, 4, 2013

 

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