7SKI
Pertussis toxin in complex with PJ34
Summary for 7SKI
| Entry DOI | 10.2210/pdb7ski/pdb |
| Descriptor | Pertussis toxin subunit 1, N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE (3 entities in total) |
| Functional Keywords | toxin, adp-ribosyltransferase, transferase, whooping cough, inhibitor, pertussis, transferase-inhibitor complex, transferase/inhibitor |
| Biological source | Bordetella pertussis |
| Total number of polymer chains | 2 |
| Total formula weight | 41412.60 |
| Authors | Littler, D.R.,Beddoe, T.,Pulliainen, A.,Rossjohn, J. (deposition date: 2021-10-20, release date: 2022-04-13, Last modification date: 2023-10-18) |
| Primary citation | Sakari, M.,Tran, M.T.,Rossjohn, J.,Pulliainen, A.T.,Beddoe, T.,Littler, D.R. Crystal structures of pertussis toxin with NAD + and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity. J.Biol.Chem., 298:101892-101892, 2022 Cited by PubMed: 35378130DOI: 10.1016/j.jbc.2022.101892 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.09912437248 Å) |
Structure validation
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