4L6T

GM1 bound form of the ECX AB5 holotoxin

Summary for 4L6T

Entry DOI	10.2210/pdb4l6t/pdb
Related	2wv6 4L63
Descriptor	ECXA, ECXB, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	cholera-like toxin, matrix metalloproteinase, bacterial mmp, metzincin, ab5, ob fold, transferase, toxin, protease, pentasacharide, gm1, ganglioside, oligosaccharide complex, toxilysin, hydrolase
Biological source	Escherichia coli More
Total number of polymer chains	6
Total formula weight	98430.05
Authors	Littler, D.R.,Ng, N.M.,Rossjohn, J.,Beddoe, T. (deposition date: 2013-06-12, release date: 2013-11-06, Last modification date: 2023-09-20)
Primary citation	Ng, N.M.,Littler, D.R.,Paton, A.W.,Le Nours, J.,Rossjohn, J.,Paton, J.C.,Beddoe, T. EcxAB Is a Founding Member of a New Family of Metalloprotease AB5 Toxins with a Hybrid Cholera-like B Subunit. Structure, 21:2003-2013, 2013 Cited by PubMed: 24095060 DOI: 10.1016/j.str.2013.08.024 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.859 Å)

Structure validation