6MVN
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![BU of 6mvn by Molmil](/molmil-images/mine/6mvn) | LasR LBD L130F:3OC10HSL complex | 分子名称: | 3-oxo-N-[(3S)-2-oxotetrahydrofuran-3-yl]decanamide, Transcriptional regulator LasR | 著者 | Bassler, B.L, Paczkowski, J.E. | 登録日 | 2018-10-26 | 公開日 | 2019-01-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural determinants driving homoserine lactone ligand selection in thePseudomonas aeruginosaLasR quorum-sensing receptor. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6MWL
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![BU of 6mwl by Molmil](/molmil-images/mine/6mwl) | LasR LBD:mBTL complex | 分子名称: | 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, Transcriptional regulator LasR | 著者 | Bassler, B.L, Paczkowski, J.E. | 登録日 | 2018-10-29 | 公開日 | 2019-04-03 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. Acs Chem.Biol., 14, 2019
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6MWZ
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![BU of 6mwz by Molmil](/molmil-images/mine/6mwz) | LasR LBD T75V/Y93F/A127W:BB0126 | 分子名称: | 4-[3-(methylsulfonyl)phenoxy]-N-[(1S,3S,5S)-2-oxobicyclo[3.1.0]hexan-3-yl]butanamide, ALA-HIS-HIS-HIS-HIS-ALA, Transcriptional regulator LasR | 著者 | Bassler, B.L, Paczkowski, J.E. | 登録日 | 2018-10-30 | 公開日 | 2019-04-03 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.657 Å) | 主引用文献 | An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. Acs Chem.Biol., 14, 2019
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6MWH
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![BU of 6mwh by Molmil](/molmil-images/mine/6mwh) | LasR LBD:BB0020 complex | 分子名称: | 2-(3-bromophenoxy)-N-[(1S,2S,3R,5S)-2-hydroxybicyclo[3.1.0]hexan-3-yl]acetamide, Transcriptional regulator LasR | 著者 | Bassler, B.L, Paczkowski, J.E. | 登録日 | 2018-10-29 | 公開日 | 2019-04-03 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. Acs Chem.Biol., 14, 2019
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6MWW
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![BU of 6mww by Molmil](/molmil-images/mine/6mww) | LasR LBD:BB0126 complex | 分子名称: | 4-[3-(methylsulfonyl)phenoxy]-N-[(1R,3R,5R)-2-oxobicyclo[3.1.0]hexan-3-yl]butanamide, Transcriptional regulator LasR | 著者 | Bassler, B.L, Paczkowski, J.E. | 登録日 | 2018-10-30 | 公開日 | 2019-04-03 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. Acs Chem.Biol., 14, 2019
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1JX6
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![BU of 1jx6 by Molmil](/molmil-images/mine/1jx6) | CRYSTAL STRUCTURE OF LUXP FROM VIBRIO HARVEYI COMPLEXED WITH AUTOINDUCER-2 | 分子名称: | 3A-METHYL-5,6-DIHYDRO-FURO[2,3-D][1,3,2]DIOXABOROLE-2,2,6,6A-TETRAOL, CALCIUM ION, LUXP PROTEIN | 著者 | Chen, X, Schauder, S, Potier, N, Van Dorsselaer, A, Pelczer, I, BassleR, B.L, Hughson, F.M. | 登録日 | 2001-09-05 | 公開日 | 2002-02-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural identification of a bacterial quorum-sensing signal containing boron. Nature, 415, 2002
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1Y6D
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![BU of 1y6d by Molmil](/molmil-images/mine/1y6d) | Solution structure and dynamics of LuxU from Vibrio harveyi, a phosphotransferase protein involved in bacterial quorum sensing | 分子名称: | Phosphorelay protein luxU | 著者 | Ulrich, D.L, Kojetin, D, Bassler, B.L, Cavanagh, J, Loria, J.P. | 登録日 | 2004-12-06 | 公開日 | 2004-12-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and dynamics of LuxU from Vibrio harveyi, a phosphotransferase protein involved in bacterial quorum sensing. J.Mol.Biol., 347, 2005
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7TZ9
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![BU of 7tz9 by Molmil](/molmil-images/mine/7tz9) | |
7TZA
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![BU of 7tza by Molmil](/molmil-images/mine/7tza) | Structure of PQS Response Protein PqsE in complex with N-(4-(3-neopentylureido)phenyl)-1H-indazole-7-carboxamide | 分子名称: | 1,2-ETHANEDIOL, FE (III) ION, N-{4-[(2,2-dimethylpropyl)carbamamido]phenyl}-1H-indazole-7-carboxamide, ... | 著者 | Jeffrey, P.D, Taylor, I.R, Bassler, B.L. | 登録日 | 2022-02-15 | 公開日 | 2022-08-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against Pseudomonas aeruginosa. Biochemistry, 61, 2022
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7U6G
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![BU of 7u6g by Molmil](/molmil-images/mine/7u6g) | |
1ZHH
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![BU of 1zhh by Molmil](/molmil-images/mine/1zhh) | Crystal Structure of the Apo Form of Vibrio Harveyi LUXP Complexed with the Periplasmic Domain of LUXQ | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Autoinducer 2 sensor kinase/phosphatase luxQ, Autoinducer 2-binding periplasmic protein luxP | 著者 | Neiditch, M.B, Federle, M.J, Miller, S.T, Bassler, B.L, Hughson, F.M. | 登録日 | 2005-04-25 | 公開日 | 2005-05-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Regulation of LuxPQ Receptor Activity by the Quorum-Sensing Signal Autoinducer-2. Mol.Cell, 18, 2005
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1TJY
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![BU of 1tjy by Molmil](/molmil-images/mine/1tjy) | Crystal Structure of Salmonella typhimurium AI-2 receptor LsrB in complex with R-THMF | 分子名称: | (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran, sugar transport protein | 著者 | Miller, S.T, Xavier, K.B, Campagna, S.R, Taga, M.E, Semmelhack, M.F, Bassler, B.L, Hughson, F.M. | 登録日 | 2004-06-07 | 公開日 | 2004-09-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Salmonella typhimurium Recognizes a Chemically Distinct Form of the Bacterial Quorum-Sensing Signal AI-2 Mol.Cell, 15, 2004
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1TM2
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![BU of 1tm2 by Molmil](/molmil-images/mine/1tm2) | Crystal Structure of the apo form of the Salmonella typhimurium AI-2 receptor LsrB | 分子名称: | sugar transport protein | 著者 | Miller, S.T, Xavier, K.B, Campagna, S.R, Taga, M.E, Semmelhack, M.F, Bassler, B.L, Hughson, F.M. | 登録日 | 2004-06-10 | 公開日 | 2004-09-28 | 最終更新日 | 2018-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Salmonella typhimurium Recognizes a Chemically Distinct Form of the Bacterial Quorum-Sensing Signal AI-2 Mol.Cell, 15, 2004
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6MVM
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![BU of 6mvm by Molmil](/molmil-images/mine/6mvm) | LasR LBD L130F:3OC14HSL complex | 分子名称: | 3-oxo-N-[(3S)-2-oxooxolan-3-yl]tetradecanamide, Transcriptional regulator LasR | 著者 | Paczkowski, J.E, Bassler, B.L. | 登録日 | 2018-10-26 | 公開日 | 2019-01-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | 主引用文献 | An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. Acs Chem.Biol., 14, 2019
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7KGX
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![BU of 7kgx by Molmil](/molmil-images/mine/7kgx) | Structure of PQS Response Protein PqsE in Complex with 4-(3-(2-methyl-2-morpholinobutyl)ureido)-N-(thiazol-2-yl)benzamide | 分子名称: | 2-aminobenzoylacetyl-CoA thioesterase, 4-({[(2R)-2-methyl-2-(morpholin-4-yl)butyl]carbamoyl}amino)-N-(1,3-thiazol-2-yl)benzamide, FE (III) ION | 著者 | Jeffrey, P.D, Taylor, I.R, Bassler, B.L. | 登録日 | 2020-10-19 | 公開日 | 2021-05-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Inhibitor Mimetic Mutations in the Pseudomonas aeruginosa PqsE Enzyme Reveal a Protein-Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production. Acs Chem.Biol., 16, 2021
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7KGW
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![BU of 7kgw by Molmil](/molmil-images/mine/7kgw) | |