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PDB: 20 results

2KJI
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A divergent ins protein in c. elegans structurally resemble insulin and activates the human insulin receptor
Descriptor: Probable insulin-like peptide beta-type 5
Authors:Hua, Q.X, Nakarawa, S.H, Wilken, R, Ramos, R.R, Jia, W.H, Bass, J, Weiss, M.A.
Deposit date:2009-05-28
Release date:2009-06-16
Last modified:2019-09-18
Method:SOLUTION NMR
Cite:A divergent INS protein in Caenorhabditis elegans structurally resembles human insulin and activates the human insulin receptor.
Genes Dev., 17, 2003
7S5U
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Extended bipolar assembly domain of kinesin-5 minifilament
Descriptor: Kinesin-like protein Klp61F
Authors:Nithianantham, S, Al-Bassam, J.
Deposit date:2021-09-12
Release date:2023-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (4.41 Å)
Cite:The kinesin-5 tail and bipolar miniflament domains are the origin of its microtubule crosslinking and sliding activity.
Mol.Biol.Cell, 2023
6VPP
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Cryo-EM structure of microtubule-bound KLP61F motor with tail domain in the nucleotide-free state
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein Klp61F, ...
Authors:Bodrug, T, Wilson-Kubalek, E.M, Nithianantham, S, Debs, G, Sindelar, C.V, Milligan, R, Al-Bassam, J.
Deposit date:2020-02-04
Release date:2020-02-19
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding.
Elife, 9, 2020
6VPO
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Cryo-EM structure of microtubule-bound KLP61F motor domain in the AMPPNP state
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein Klp61F, ...
Authors:Bodrug, T, Wilson-Kubalek, E.M, Nithianantham, S, Debs, G, Sindelar, C.V, Milligan, R, Al-Bassam, J.
Deposit date:2020-02-04
Release date:2020-02-19
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding.
Elife, 9, 2020
5CYA
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Crystal structure of Arl2 GTPase-activating protein tubulin cofactor C (TBCC)
Descriptor: SULFATE ION, Tubulin-specific chaperone C
Authors:Nithianantham, S, Le, S, Seto, E, Jia, W, Leary, J, Corbett, K.D, Moore, J.K, Al-Bassam, J.
Deposit date:2015-07-30
Release date:2015-08-12
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Tubulin cofactors and Arl2 are cage-like chaperones that regulate the soluble alpha beta-tubulin pool for microtubule dynamics.
Elife, 4, 2015
6MZG
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Structural Basis of Tubulin Recruitment and Assembly by Microtubule Polymerases with Tumor Overexpressed Gene (TOG) Domain Arrays
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Nithianantham, S, Al-Bassam, J.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.208 Å)
Cite:Structural basis of tubulin recruitment and assembly by microtubule polymerases with Tumor Overexpressed Gene (TOG) domain arrays.
Elife, 7, 2018
6B5D
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BU of 6b5d by Molmil
Structural Basis for Katanin Self-Assembly
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Meiotic spindle formation protein mei-1
Authors:Nithianantham, S, Al-Bassam, J.
Deposit date:2017-09-29
Release date:2018-05-23
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for disassembly of katanin heterododecamers.
J. Biol. Chem., 293, 2018
6B5C
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Structural Basis for Katanin Self-Assembly
Descriptor: Katanin p60 ATPase-containing subunit A-like 1, TETRAETHYLENE GLYCOL
Authors:Nithianantham, S, Al-Bassam, J.
Deposit date:2017-09-29
Release date:2018-05-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for disassembly of katanin heterododecamers.
J. Biol. Chem., 293, 2018
6MZE
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Structural Basis of Tubulin Recruitment and Assembly by Microtubule Polymerases with Tumor Overexpressed Gene (TOG) Domain Arrays
Descriptor: Designed ankyrin repeat protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Nithianantham, S, Al-Bassam, J.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis of tubulin recruitment and assembly by microtubule polymerases with Tumor Overexpressed Gene (TOG) domain arrays.
Elife, 7, 2018
6MZF
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Structural Basis of Tubulin Recruitment and Assembly by Microtubule Polymerases with Tumor Overexpressed Gene (TOG) Domain Arrays
Descriptor: Designed ankyrin repeat protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Nithianantham, S, Al-Bassam, J.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Structural basis of tubulin recruitment and assembly by microtubule polymerases with Tumor Overexpressed Gene (TOG) domain arrays.
Elife, 7, 2018
4PXU
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BU of 4pxu by Molmil
Structural basis for the assembly of the mitotic motor kinesin-5 into bipolar tetramers
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Bipolar kinesin KRP-130
Authors:Scholey, J.E, Nithianantham, S, Scholey, J.M, Al-Bassam, J.
Deposit date:2014-03-25
Release date:2014-04-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Structural basis for the assembly of the mitotic motor Kinesin-5 into bipolar tetramers.
Elife, 3, 2014
4PXT
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BU of 4pxt by Molmil
Structural basis for the assembly of the mitotic motor kinesin-5 into bipolar tetramers
Descriptor: Bipolar kinesin KRP-130
Authors:Scholey, J.E, Nithianantham, S, Scholey, J.M, Al-Bassam, J.
Deposit date:2014-03-25
Release date:2014-04-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for the assembly of the mitotic motor Kinesin-5 into bipolar tetramers.
Elife, 3, 2014
5JCS
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BU of 5jcs by Molmil
CRYO-EM STRUCTURE OF THE RIX1-REA1 PRE-60S PARTICLE
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Barrio-Garcia, C, Thoms, M, Flemming, D, Kater, L, Berninghausen, O, Bassler, J, Beckmann, R, Hurt, E.
Deposit date:2016-04-15
Release date:2016-11-16
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Architecture of the Rix1-Rea1 checkpoint machinery during pre-60S-ribosome remodeling
Nat.Struct.Mol.Biol., 23, 2016
2OF3
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BU of 2of3 by Molmil
TOG domain structure from C.elegans Zyg9
Descriptor: ZYG-9
Authors:Al-Bassam, J, Larsen, N.A, Hyman, A.A, Harrison, S.C.
Deposit date:2007-01-02
Release date:2007-03-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a TOG domain: conserved features of XMAP215/Dis1-family TOG domains and implications for tubulin binding.
Structure, 15, 2007
8BGU
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BU of 8bgu by Molmil
human MDM2-5S RNP
Descriptor: 5S rRNA, 60S ribosomal protein L11, 60S ribosomal protein L5, ...
Authors:Castillo, N, Thoms, M, Flemming, D, Hammaren, H.M, Buschauer, R, Ameismeier, M, Bassler, J, Beck, M, Beckmann, R, Hurt, E.
Deposit date:2022-10-28
Release date:2023-06-14
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of nascent 5S RNPs at the crossroad between ribosome assembly and MDM2-p53 pathways.
Nat.Struct.Mol.Biol., 30, 2023
4WJV
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BU of 4wjv by Molmil
Crystal structure of Rsa4 in complex with the Nsa2 binding peptide
Descriptor: Maltose-binding periplasmic protein, Ribosome assembly protein 4, Ribosome biogenesis protein NSA2, ...
Authors:Holdermann, I, Paternoga, H, Bassler, J, Hurt, E, Sinning, I.
Deposit date:2014-10-01
Release date:2014-11-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation.
J.Cell Biol., 207, 2014
4WJS
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BU of 4wjs by Molmil
Crystal structure of Rsa4 from Chaetomium thermophilum
Descriptor: Rsa4
Authors:Holdermann, I, Bassler, J, Hurt, E, Sinning, I.
Deposit date:2014-10-01
Release date:2014-11-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation.
J.Cell Biol., 207, 2014
4WJU
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BU of 4wju by Molmil
Crystal structure of Rsa4 from Saccharomyces cerevisiae
Descriptor: GLYCEROL, Ribosome assembly protein 4
Authors:Holdermann, I, Bassler, J, Hurt, E, Sinning, I.
Deposit date:2014-10-01
Release date:2014-11-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation.
J.Cell Biol., 207, 2014
7OZS
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BU of 7ozs by Molmil
Structure of the hexameric 5S RNP from C. thermophilum
Descriptor: 5S rRNA, 60S ribosomal protein l5-like protein, Putative ribosomal protein, ...
Authors:Castillo, N, Thoms, M, Flemming, D, Hammaren, H.M, Buschauer, R, Ameismeier, M, Bassler, J, Beck, M, Beckmann, R, Hurt, E.
Deposit date:2021-06-28
Release date:2022-10-12
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of nascent 5S RNPs at the crossroad between ribosome assembly and MDM2-p53 pathways.
Nat.Struct.Mol.Biol., 2023
2MVF
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Structural insight into an essential assembly factor network on the pre-ribosome
Descriptor: Uncharacterized protein
Authors:Lee, W, Bassler, J, Paternoga, H, Holdermann, I, Thomas, M, Granneman, S, Barrio-Garcia, C, Nyarko, A, Stier, G, Clark, S.A, Schraivogel, D, Kallas, M, Beckmann, R, Tollervey, D, Barbar, E, Sinning, I, Hurt, E.
Deposit date:2014-10-02
Release date:2014-12-03
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation.
J.Cell Biol., 207, 2014

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