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PDB: 36 件
2M5X
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Novel method of protein purification for structural research. Example of ultra high resolution structure of SPI-2 inhibitor by X-ray and NMR spectroscopy.
分子名称: Silk protease inhibitor 2
著者Lenarcic Zivkovic, M, Dvornyk, A, Kludkiewicz, B, Kopera, E, Zagorski-Ostoja, W, Grzelak, K, Zhukov, I, Bal, W.
登録日2013-03-12
公開日2014-03-12
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献Atomic resolution structure of a protein prepared by non-enzymatic His-tag removal. Crystallographic and NMR study of GmSPI-2 inhibitor.
Plos One, 9, 2014
4HGU
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Crystal Structure of Galleria mellonella Silk Protease Inhibitor 2
分子名称: SODIUM ION, Silk protease inhibitor 2
著者Krzywda, S, Jaskolski, M, Dvornyk, A, Kludkiewicz, B, Grzelak, K, Zagorski, W, Bal, W, Kopera, E.
登録日2012-10-08
公開日2013-10-09
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (0.98 Å)
主引用文献Atomic resolution structure of a protein prepared by non-enzymatic His-tag removal. Crystallographic and NMR study of GmSPI-2 inhibitor.
Plos One, 9, 2014
3BMP
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HUMAN BONE MORPHOGENETIC PROTEIN-2 (BMP-2)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, PROTEIN (BONE MORPHOGENETIC PROTEIN 2 (BMP-2))
著者Scheufler, C, Sebald, W, Huelsmeyer, M.
登録日1999-03-12
公開日2000-03-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of human bone morphogenetic protein-2 at 2.7 A resolution.
J.Mol.Biol., 287, 1999
3BK3
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Crystal structure of the complex of BMP-2 and the first Von Willebrand domain type C of Crossveinless-2
分子名称: Bone morphogenetic protein 2, Crossveinless 2
著者Mueller, T.D, Sebald, W, Zhang, J.-L.
登録日2007-12-05
公開日2008-05-27
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure analysis reveals how the Chordin family member crossveinless 2 blocks BMP-2 receptor binding
Dev.Cell, 14, 2008
3NH7
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BU of 3nh7 by Molmil
Crystal structure of the neutralizing Fab fragment AbD1556 bound to the BMP type I receptor IA
分子名称: Antibody fragment Fab AbD1556, heavy chain, light chain, ...
著者Mueller, T.D, Harth, S, Sebald, W.
登録日2010-06-14
公開日2010-10-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A selection fit mechanism in BMP receptor IA as a possible source for BMP ligand-receptor promiscuity
Plos One, 5, 2010
8A4F
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Human Interleukin-4 mutant - C3T-IL4
分子名称: Interleukin-4
著者Vaz, D.C, Rodrigues, J.R, Mueller, T.D, Sebald, W, Redfield, C, Brito, R.M.M.
登録日2022-06-11
公開日2023-10-18
最終更新日2024-10-16
実験手法SOLUTION NMR
主引用文献Lessons on protein structure from interleukin-4: All disulfides are not created equal.
Proteins, 92, 2024
8CH7
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RDC-refined Interleukin-4 (wild type) pH 5.6
分子名称: Interleukin-4
著者Vaz, D.C, Rodrigues, J.R, Loureiro-Ferreira, N, Mueller, T, Sebald, W, Redfield, C, Brito, R.M.M.
登録日2023-02-07
公開日2023-10-18
最終更新日2024-01-17
実験手法SOLUTION NMR
主引用文献Lessons on protein structure from interleukin-4: All disulfides are not created equal.
Proteins, 92, 2024
8CGF
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Interleukin-4 (wild type) pH 2.4
分子名称: Interleukin-4
著者Vaz, D.C, Rodrigues, J.R, Loureiro-Ferreira, N, Mueller, T, Sebald, W, Redfield, C, Brito, R.M.M.
登録日2023-02-04
公開日2023-10-18
最終更新日2024-10-09
実験手法SOLUTION NMR
主引用文献Lessons on protein structure from interleukin-4: All disulfides are not created equal.
Proteins, 92, 2024
1LV0
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Crystal structure of the Rab effector guanine nucleotide dissociation inhibitor (GDI) in complex with a geranylgeranyl (GG) peptide
分子名称: GERAN-8-YL GERAN, RAB GDP disossociation inhibitor alpha, SULFATE ION
著者An, Y, Shao, Y, Alory, C, Matteson, J, Sakisaka, T, Chen, W, Gibbs, R.A, Wilson, I.A, Balch, W.E.
登録日2002-05-23
公開日2003-08-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Geranylgeranyl switching regulates GDI-Rab GTPase recycling.
Structure, 11, 2003
5N4K
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BU of 5n4k by Molmil
N-terminal domain of a human Coronavirus NL63 nucleocapsid protein
分子名称: Nucleoprotein, SULFATE ION
著者Zdzalik, M, Szelazek, B, Kabala, W, Golik, P, Burmistrz, M, Florek, D, Kus, K, Pyrc, K, Dubin, G.
登録日2017-02-10
公開日2017-02-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Structural Characterization of Human Coronavirus NL63 N Protein.
J. Virol., 91, 2017
5EPW
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C-Terminal Domain Of Human Coronavirus Nl63 Nucleocapsid Protein
分子名称: Nucleoprotein
著者Szelazek, B, Kabala, W, Kus, K, Zdzalik, M, Golik, P, Florek, D, Burmistrz, M, Pyrc, K, Dubin, G.
登録日2015-11-12
公開日2017-02-22
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Characterization of Human Coronavirus NL63 N Protein.
J. Virol., 91, 2017
1IAR
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BU of 1iar by Molmil
INTERLEUKIN-4 / RECEPTOR ALPHA CHAIN COMPLEX
分子名称: PROTEIN (INTERLEUKIN-4 RECEPTOR ALPHA CHAIN), PROTEIN (INTERLEUKIN-4)
著者Hage, T, Sebald, W, Reinemer, P.
登録日1999-02-25
公開日2000-03-03
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the interleukin-4/receptor alpha chain complex reveals a mosaic binding interface.
Cell(Cambridge,Mass.), 97, 1999
2MBK
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The Clip-segment of the von Willebrand domain 1 of the BMP modulator protein Crossveinless 2 is preformed
分子名称: Crossveinless 2
著者Mueller, T.D, Fiebig, J.E, Weidauer, S.E, Qiu, L, Bauer, M, Schmieder, P, Beerbaum, M, Zhang, J, Oschkinat, H, Sebald, W.
登録日2013-08-02
公開日2013-10-16
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献The Clip-Segment of the von Willebrand Domain 1 of the BMP Modulator Protein Crossveinless 2 Is Preformed.
Molecules, 18, 2013
2H64
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Crystal structure of a ternary ligand-receptor complex of BMP-2
分子名称: Acvr2b protein, Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
著者Mueller, T.D, Sebald, W, Weber, D.
登録日2006-05-30
公開日2007-04-10
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor.
Bmc Struct.Biol., 7, 2007
2R52
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BU of 2r52 by Molmil
Crystal structure analysis of Bone Morphogenetic Protein-6 (BMP-6)
分子名称: Bone morphogenetic protein 6, ISOPROPYL ALCOHOL
著者Mueller, T.D, Sebald, W, Saremba, S.
登録日2007-09-03
公開日2008-01-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand.
Febs J., 275, 2007
2W9P
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BU of 2w9p by Molmil
Crystal Structure of Potato Multicystatin
分子名称: MULTICYSTATIN
著者Nissen, M.S, Kumar, G.N, Youn, B, Knowles, D.B, Lam, K.S, Ballinger, W.J, Knowles, N.R, Kang, C.
登録日2009-01-28
公開日2010-02-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Characterization of Solanum Tuberosum Multicystatin and its Structural Comparison with Other Cystatins.
Plant Cell, 21, 2009
2W9Q
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Crystal Structure of Potato Multicystatin-P212121
分子名称: MULTICYSTATIN
著者Nissen, M.S, Kumar, G.N, Youn, B, Knowles, D.B, Lam, K.S, Ballinger, W.J, Knowles, N.R, Kang, C.
登録日2009-01-28
公開日2010-02-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Characterization of Solanum Tuberosum Multicystatin and its Structural Comparison with Other Cystatins.
Plant Cell, 21, 2009
2R53
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Crystal structure analysis of Bone Morphogenetic Protein-6 variant B2 (B2-BMP-6)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Bone morphogenetic protein 6
著者Mueller, T.D, Sebald, W.
登録日2007-09-03
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand.
Febs J., 275, 2007
1D5T
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BU of 1d5t by Molmil
GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR, ALPHA-ISOFORM
分子名称: GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR, SULFATE ION
著者Peng, L, Zeng, K, Heine, A, Moyer, B, Greasley, S.E, Kuhn, P, Balch, W.E, Wilson, I.A.
登録日1999-10-11
公開日2000-10-25
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.04 Å)
主引用文献A new functional domain of guanine nucleotide dissociation inhibitor (alpha-GDI) involved in Rab recycling.
Traffic, 1, 2000
3QT2
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BU of 3qt2 by Molmil
Structure of a cytokine ligand-receptor complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Interleukin-5, Interleukin-5 receptor subunit alpha, ...
著者Mueller, T.D, Patino, E, Kotzsch, A, Saremba, S, Nickel, J, Schmitz, W, Sebald, W.
登録日2011-02-22
公開日2012-02-01
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure Analysis of the IL-5 Ligand-Receptor Complex Reveals a Wrench-like Architecture for IL-5Ralpha.
Structure, 19, 2011
1WAQ
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BU of 1waq by Molmil
Crystal structure of human Growth and Differentiation Factor 5 (GDF-5)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GROWTH/DIFFERENTIATION FACTOR 5
著者Mueller, T.D, Nickel, J, Sebald, W.
登録日2004-10-27
公開日2005-05-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献A Single Residue of Gdf-5 Defines Binding Specificity to Bmp Receptor Ib.
J.Mol.Biol., 349, 2005
1REU
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BU of 1reu by Molmil
Structure of the bone morphogenetic protein 2 mutant L51P
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, bone morphogenetic protein 2
著者Keller, S, Nickel, J, Zhang, J.-L, Sebald, W, Mueller, T.D.
登録日2003-11-07
公開日2004-05-04
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Molecular recognition of BMP-2 and BMP receptor IA.
Nat.Struct.Mol.Biol., 11, 2004
3QB4
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Crystal structure of a TGF-beta ligand-receptor complex
分子名称: Bone morphogenetic protein receptor type-1A, Growth/differentiation factor 5
著者Mueller, T.D, Nickel, J, Sebald, W.
登録日2011-01-12
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献GDF-5 can act as a context-dependent BMP-2 antagonist.
Bmc Biol., 13, 2015
2CYK
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ASPECTS OF RECEPTOR BINDING AND SIGNALLING OF INTERLEUKIN-4 INVESTIGATED BY SITE-DIRECTED MUTAGENESIS AND NMR SPECTROSCOPY
分子名称: INTERLEUKIN-4
著者Mueller, T, Sebald, W, Oschkinat, H.
登録日1994-08-16
公開日1994-12-20
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献Aspects of receptor binding and signalling of interleukin-4 investigated by site-directed mutagenesis and NMR spectroscopy.
J.Mol.Biol., 237, 1994
2B8X
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Crystal structure of the interleukin-4 variant F82D
分子名称: Interleukin-4, SULFATE ION
著者Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
登録日2005-10-10
公開日2006-05-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006

 

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